Lineage for d1hwkd2 (1hwk D:463-586,D:704-860)

  1. Root: SCOP 1.59
  2. 128814Class d: Alpha and beta proteins (a+b) [53931] (208 folds)
  3. 139893Fold d.179: Substrate-binding domain of HMG-CoA reductase [56541] (1 superfamily)
  4. 139894Superfamily d.179.1: Substrate-binding domain of HMG-CoA reductase [56542] (1 family) (S)
  5. 139895Family d.179.1.1: Substrate-binding domain of HMG-CoA reductase [56543] (1 protein)
  6. 139896Protein Substrate-binding domain of HMG-CoA reductase [56544] (2 species)
  7. 139897Species Human (Homo sapiens) [TaxId:9606] [56545] (9 PDB entries)
  8. 139921Domain d1hwkd2: 1hwk D:463-586,D:704-860 [61337]
    Other proteins in same PDB: d1hwka1, d1hwkb1, d1hwkc1, d1hwkd1

Details for d1hwkd2

PDB Entry: 1hwk (more details), 2.22 Å

PDB Description: complex of the catalytic portion of human hmg-coa reductase with atorvastatin

SCOP Domain Sequences for d1hwkd2:

Sequence, based on SEQRES records: (download)

>d1hwkd2 d.179.1.1 (D:463-586,D:704-860) Substrate-binding domain of HMG-CoA reductase {Human (Homo sapiens)}
sdaeiiqlvnakhipaykletliethergvsirrqllskklsepsslqylpyrdynyslv
mgaccenvigympipvgvagplcldekefqvpmattegclvastnrgcraiglgggassr
vladXksvvceavipakvvrevlkttteamievninknlvgsamagsiggynahaanivt
aiyiacgqdaaqnvgssncitlmeasgptnedlyisctmpsieigtvgggtnllpqqacl
qmlgvqgackdnpgenarqlarivcgtvmagelslmaalaag

Sequence, based on observed residues (ATOM records): (download)

>d1hwkd2 d.179.1.1 (D:463-586,D:704-860) Substrate-binding domain of HMG-CoA reductase {Human (Homo sapiens)}
sdaeiiqletliethergvsirrqllskklsepsslqylpyrdynyslvmgaccenvigy
mpipvgvagplcldekefqvpmattegclvastnrgcraiglgggassrvladXksvvce
avipakvvrevlkttteamievninknlvgsamagsiggynahaanivtaiyiacgqdaa
qnvgssncitlmeasgptnedlyisctmpsieigtvgggtnllpqqaclqmlgvqgackd
npgenarqlarivcgtvmagelslmaalaag

SCOP Domain Coordinates for d1hwkd2:

Click to download the PDB-style file with coordinates for d1hwkd2.
(The format of our PDB-style files is described here.)

Timeline for d1hwkd2: