Lineage for d1hwka2 (1hwk A:442-586,A:704-861)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 738974Fold d.179: Substrate-binding domain of HMG-CoA reductase [56541] (1 superfamily)
    unusual fold
  4. 738975Superfamily d.179.1: Substrate-binding domain of HMG-CoA reductase [56542] (1 family) (S)
  5. 738976Family d.179.1.1: Substrate-binding domain of HMG-CoA reductase [56543] (1 protein)
  6. 738977Protein Substrate-binding domain of HMG-CoA reductase [56544] (2 species)
  7. 738978Species Human (Homo sapiens) [TaxId:9606] [56545] (9 PDB entries)
  8. 738991Domain d1hwka2: 1hwk A:442-586,A:704-861 [61331]
    Other proteins in same PDB: d1hwka1, d1hwkb1, d1hwkc1, d1hwkd1

Details for d1hwka2

PDB Entry: 1hwk (more details), 2.22 Å

PDB Description: complex of the catalytic portion of human hmg-coa reductase with atorvastatin
PDB Compounds: (A:) hmg-coa reductase

SCOP Domain Sequences for d1hwka2:

Sequence, based on SEQRES records: (download)

>d1hwka2 d.179.1.1 (A:442-586,A:704-861) Substrate-binding domain of HMG-CoA reductase {Human (Homo sapiens) [TaxId: 9606]}
prpneeclqilgnaekgakflsdaeiiqlvnakhipaykletliethergvsirrqllsk
klsepsslqylpyrdynyslvmgaccenvigympipvgvagplcldekefqvpmattegc
lvastnrgcraiglgggassrvladXksvvceavipakvvrevlkttteamievninknl
vgsamagsiggynahaanivtaiyiacgqdaaqnvgssncitlmeasgptnedlyisctm
psieigtvgggtnllpqqaclqmlgvqgackdnpgenarqlarivcgtvmagelslmaal
aagh

Sequence, based on observed residues (ATOM records): (download)

>d1hwka2 d.179.1.1 (A:442-586,A:704-861) Substrate-binding domain of HMG-CoA reductase {Human (Homo sapiens) [TaxId: 9606]}
prpneecllsdaeiiqlvnakhipaykletliethergvsirrqllskklsepsslqylp
yrdynyslvmgaccenvigympipvgvagplcldekefqvpmattegclvastnrgcrai
glgggassrvladXksvvceavipakvvrevlkttteamievninknlvgsamagsiggy
nahaanivtaiyiacgqdaaqnvgssncitlmeasgptnedlyisctmpsieigtvgggt
nllpqqaclqmlgvqgackdnpgenarqlarivcgtvmagelslmaalaagh

SCOP Domain Coordinates for d1hwka2:

Click to download the PDB-style file with coordinates for d1hwka2.
(The format of our PDB-style files is described here.)

Timeline for d1hwka2: