Lineage for d1hwka1 (1hwk A:587-703)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2192663Fold d.58: Ferredoxin-like [54861] (59 superfamilies)
    alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2
  4. 2197354Superfamily d.58.20: NAD-binding domain of HMG-CoA reductase [55035] (1 family) (S)
  5. 2197355Family d.58.20.1: NAD-binding domain of HMG-CoA reductase [55036] (1 protein)
  6. 2197356Protein NAD-binding domain of HMG-CoA reductase [55037] (2 species)
  7. 2197357Species Human (Homo sapiens) [TaxId:9606] [55038] (9 PDB entries)
  8. 2197370Domain d1hwka1: 1hwk A:587-703 [61330]
    Other proteins in same PDB: d1hwka2, d1hwkb2, d1hwkc2, d1hwkd2
    complexed with 117, adp

Details for d1hwka1

PDB Entry: 1hwk (more details), 2.22 Å

PDB Description: complex of the catalytic portion of human hmg-coa reductase with atorvastatin
PDB Compounds: (A:) hmg-coa reductase

SCOPe Domain Sequences for d1hwka1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1hwka1 d.58.20.1 (A:587-703) NAD-binding domain of HMG-CoA reductase {Human (Homo sapiens) [TaxId: 9606]}
gmtrgpvvrlpracdsaevkawletsegfavikeafdstsrfarlqklhtsiagrnlyir
fqsrsgdamgmnmiskgtekalsklheyfpemqilavsgnyctdkkpaainwiegrg

SCOPe Domain Coordinates for d1hwka1:

Click to download the PDB-style file with coordinates for d1hwka1.
(The format of our PDB-style files is described here.)

Timeline for d1hwka1: