SCOP 1.69: Domain d1hw9b1: 1hw9 B:587-703

Lineage for d1hw9b1 (1hw9 B:587-703)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.58: Ferredoxin-like [54861] (49 superfamilies)
   alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2

4. Superfamily d.58.20: NAD-binding domain of HMG-CoA reductase [55035] (1 family)

5. Family d.58.20.1: NAD-binding domain of HMG-CoA reductase [55036] (1 protein)

6. Protein NAD-binding domain of HMG-CoA reductase [55037] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55038] (9 PDB entries)

8. Domain d1hw9b1: 1hw9 B:587-703 [61308]
   Other proteins in same PDB: d1hw9a2, d1hw9b2, d1hw9c2, d1hw9d2

Details for d1hw9b1

PDB Entry: 1hw9, 2.33 Å

PDB Description: complex of the catalytic portion of human hmg-coa reductase with simvastatin

SCOP Domain Sequences for d1hw9b1:

Sequence; same for both SEQRES and ATOM records:

>d1hw9b1 d.58.20.1 (B:587-703) NAD-binding domain of HMG-CoA reductase {Human (Homo sapiens)}
gmtrgpvvrlpracdsaevkawletsegfavikeafdstsrfarlqklhtsiagrnlyir
fqsrsgdamgmnmiskgtekalsklheyfpemqilavsgnyctdkkpaainwiegrg

Timeline for d1hw9b1:

• d1hw9b1 first appeared in SCOP 1.57
  
• d1hw9b1 appears in SCOP 1.67
  
• d1hw9b1 appears in SCOP 1.71
  
• d1hw9b1 appears in the current release, SCOPe 2.08