SCOP 1.67: Domain d1hmua1: 1hmu A:26-335

Lineage for d1hmua1 (1hmu A:26-335)

1. Root: SCOP 1.67

2. Class a: All alpha proteins [46456] (202 folds)

3. Fold a.102: alpha/alpha toroid [48207] (5 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.3: Chondroitin AC/alginate lyase [48230] (2 families)
   incomplete toroid

5. Family a.102.3.2: Hyaluronate lyase-like catalytic, N-terminal domain [48234] (4 proteins)

6. Protein Chondroitinase AC [48235] (2 species)
   Chondroitin AC lyase

7. Species Pedobacter heparinus (Flavobacterium heparinum) [TaxId:984] [48236] (5 PDB entries)

8. Domain d1hmua1: 1hmu A:26-335 [61089]
   Other proteins in same PDB: d1hmua2, d1hmua3
   complexed with ca, gcu, idt, man, mxy, ngl, ram, xys; mutant

Details for d1hmua1

PDB Entry: 1hmu, 2 Å

PDB Description: active site of chondroitinase ac lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis

SCOP Domain Sequences for d1hmua1:

Sequence; same for both SEQRES and ATOM records:

>d1hmua1 a.102.3.2 (A:26-335) Chondroitinase AC {Pedobacter heparinus (Flavobacterium heparinum)}
gtaelimkrvmldlkkplrnmdkvaeknlntlqpdgswkdvpykddamtnwlpnnhllql
etiiqayiekdshyygddkvfdqiskafkywydsdpksrnwwhneiatpqalgemlilmr
ygkkpldealvhkltermkrgepekktganktdialhyfyralltsdeallsfavkelfy
pvqfvhyeeglqydysylqhgpqlqissygavfitgvlklanyvrdtpyalsteklaifs
kyyrdsylkairgsymdfnvegrgvsrpdilnkkaekkrllvakmidlkhteewadaiar
tdstvaagyk

Timeline for d1hmua1:

• d1hmua1 first appeared in SCOP 1.57
  
• d1hmua1 appears in SCOP 1.65
  
• d1hmua1 appears in SCOP 1.69
  
• d1hmua1 appears in the current release, SCOPe 2.08