SCOP 1.73: Domain d1heub2: 1heu B:164-339

Lineage for d1heub2 (1heu B:164-339)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (16 proteins)
   N-terminal all-beta domain defines family

6. Protein Alcohol dehydrogenase [51737] (9 species)

7. Species Horse (Equus caballus) [TaxId:9796] [51738] (36 PDB entries)

8. Domain d1heub2: 1heu B:164-339 [60982]
   Other proteins in same PDB: d1heua1, d1heub1
   complexed with cd, mpd, nad

Details for d1heub2

PDB Entry: 1heu, 1.15 Å

PDB Description: atomic x-ray structure of liver alcohol dehydrogenase containing cadmium and a hydroxide adduct to nadh

PDB Compounds: (B:) alcohol dehydrogenase e chain

SCOP Domain Sequences for d1heub2:

Sequence; same for both SEQRES and ATOM records:

>d1heub2 c.2.1.1 (B:164-339) Alcohol dehydrogenase {Horse (Equus caballus) [TaxId: 9796]}
splekvcligcgfstgygsavkvakvtqgstcavfglggvglsvimgckaagaariigvd
inkdkfakakevgatecvnpqdykkpiqevltemsnggvdfsfevigrldtmvtalsccq
eaygvsvivgvppdsqnlsmnpmlllsgrtwkgaifggfkskdsvpklvadfmakk

Timeline for d1heub2:

• d1heub2 first appeared in SCOP 1.57
  
• d1heub2 appears in SCOP 1.71
  
• d1heub2 appears in SCOP 1.75
  
• d1heub2 appears in the current release, SCOPe 2.08