SCOPe 2.08: Domain d1fxh.1: 1fxh A:,B:

Lineage for d1fxh.1 (1fxh A:,B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.2: Penicillin acylase, catalytic domain [56244] (3 proteins)

6. Protein Penicillin acylase [56245] (2 species)
   also contains 2 all-alpha and a beta-barrel domains
   will be divided into domains in future release

7. Species Escherichia coli [TaxId:562] [56246] (24 PDB entries)

8. Domain d1fxh.1: 1fxh A:,B: [60104]
   complexed with ca, pac; mutant

Details for d1fxh.1

PDB Entry: 1fxh, 1.97 Å

PDB Description: mutant of penicillin acylase impaired in catalysis with phenylacetic acid in the active site

PDB Compounds: (A:) penicillin acylase, (B:) penicillin acylase

SCOPe Domain Sequences for d1fxh.1:

Sequence; same for both SEQRES and ATOM records:

>g1fxh.1 d.153.1.2 (A:,B:) Penicillin acylase {Escherichia coli [TaxId: 562]}
ssseikivrdeygmphiyandtwhlfygygyvvaqdrlfqmemarrstqgtvaevlgkdf
vkfdkdirrnywpdairaqiaalspedmsilqgyadgmnawidkvntnpetllpkqfntf
gftpkrwepfdvamifvgtmanrfsdstseidnlalltalkdkygvsqgmavfnqlkwlv
npsapttiavqesnyplkfnqqnsqtXsnmwvigkskaqdakaimvngpqfgwyapayty
giglhgagydvtgntpfaypglvfghngviswgstagfgddvdifaerlsaekpgyylhn
gkwvkmlsreetitvkngqaetftvwrtvhgnilqtdqttqtayaksrawdgkelaslla
wthqmkaknwqewtqqaakqaltinwyyadvngnigyvhtgaypdrqsghdprlpvpgtg
kwdwkgllpfemnpkvynpqsgyianwanspqkdypasdlfaflwggadrvteidrlleq
kprltadqawdvirqtsrqdlnlrlflptlqaatsgltqsdprrqlvetltrwdginlln
ddgktwqqpgsailnvwltsmlkrtvvaavpmpfdkwysasgyettqdgptgslnisvga
kilyeavqgdkspipqavdlfagkpqqevvlaaledtwetlskrygnnvsnwktpamalt
frannffgvpqaaaeetrhqaeyqnrgtendmivfspttsdrpvlawdvvapgqsgfiap
dgtvdkhyedqlkmyenfgrkslwltkqdveahkesqevlhvqr

Timeline for d1fxh.1:

• d1fxh.1 first appeared in SCOP 1.57
  
• d1fxh.1 appears in SCOPe 2.07