SCOPe 2.07: Domain d1fvrb_: 1fvr B:

Lineage for d1fvrb_ (1fvr B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Tie2 kinase [64406] (1 species)
   PTK group; Tie/Tck subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [64407] (1 PDB entry)

8. Domain d1fvrb_: 1fvr B: [60048]

Details for d1fvrb_

PDB Entry: 1fvr, 2.2 Å

PDB Description: tie2 kinase domain

PDB Compounds: (B:) tyrosine-protein kinase tie-2

SCOPe Domain Sequences for d1fvrb_:

Sequence, based on SEQRES records:

>d1fvrb_ d.144.1.7 (B:) Tie2 kinase {Human (Homo sapiens) [TaxId: 9606]}
ptiypvldwndikfqdvigegnfgqvlkarikkdglrmdaaikrmkeyaskddhrdfage
levlcklghhpniinllgacehrgylylaieyaphgnlldflrksrvletdpafaianst
astlssqqllhfaadvargmdylsqkqfihrdlaarnilvgenyvakiadfglsrgqevy
vkktmgrlpvrwmaieslnysvyttnsdvwsygvllweivslggtpycgmtcaelyeklp
qgyrlekplncddevydlmrqcwrekpyerpsfaqilvslnrmleerktyvnttlyekft
yagidcsae

Sequence, based on observed residues (ATOM records):

>d1fvrb_ d.144.1.7 (B:) Tie2 kinase {Human (Homo sapiens) [TaxId: 9606]}
ptiypvldwndikfqdvigegnfgqvlkarikkdglrmdaaikrmkeyrdfagelevlck
lghhpniinllgacehrgylylaieyaphgnlldflrksrvletdpafaianstastlss
qqllhfaadvargmdylsqkqfihrdlaarnilvgenyvakiadfglsrgqevyvkkrlp
vrwmaieslnysvyttnsdvwsygvllweivslggtpycgmtcaelyeklpqgyrlekpl
ncddevydlmrqcwrekpyerpsfaqilvslnrmleerktyvnttlyekftyagidcsae

Timeline for d1fvrb_:

• d1fvrb_ first appeared in SCOP 1.57
  
• d1fvrb_ appears in SCOPe 2.06
  
• d1fvrb_ appears in the current release, SCOPe 2.08