SCOP 1.65: Domain d1fpzf_: 1fpz F:

Lineage for d1fpzf_ (1fpz F:)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1432

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (2 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.1: Dual specificity phosphatase-like [52800] (6 proteins)

6. Protein Kinase associated phosphatase (kap) [64049] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [64050] (2 PDB entries)

8. Domain d1fpzf_: 1fpz F: [59981]
   complexed with so4; mutant

Details for d1fpzf_

PDB Entry: 1fpz, 2 Å

PDB Description: crystal structure analysis of kinase associated phosphatase (kap) with a substitution of the catalytic site cysteine (cys140) to a serine

SCOP Domain Sequences for d1fpzf_:

Sequence; same for both SEQRES and ATOM records:

>d1fpzf_ c.45.1.1 (F:) Kinase associated phosphatase (kap) {Human (Homo sapiens)}
eqtpihiswlslsrvncsqflglcalpgckfkdvrrnvqkdteelkscgiqdifvfctrg
elskyrvpnlldlyqqcgiithhhpiadggtpdiascceimeelttclknyrktlihsyg
glgrsclvaaclllylsdtispeqaidslrdlrgsgaiqtikqynylhefrdklaahl

Timeline for d1fpzf_:

• d1fpzf_ first appeared in SCOP 1.57
  
• d1fpzf_ appears in SCOP 1.63
  
• d1fpzf_ appears in SCOP 1.67
  
• d1fpzf_ appears in the current release, SCOPe 2.08