SCOPe 2.05: Domain d1fpzd_: 1fpz D:

Lineage for d1fpzd_ (1fpz D:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.1: Dual specificity phosphatase-like [52800] (9 proteins)

6. Protein Kinase associated phosphatase (kap) [64049] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [64050] (2 PDB entries)

8. Domain d1fpzd_: 1fpz D: [59979]
   complexed with so4

Details for d1fpzd_

PDB Entry: 1fpz, 2 Å

PDB Description: crystal structure analysis of kinase associated phosphatase (kap) with a substitution of the catalytic site cysteine (cys140) to a serine

PDB Compounds: (D:) cyclin-dependent kinase inhibitor 3

SCOPe Domain Sequences for d1fpzd_:

Sequence; same for both SEQRES and ATOM records:

>d1fpzd_ c.45.1.1 (D:) Kinase associated phosphatase (kap) {Human (Homo sapiens) [TaxId: 9606]}
eqtpihiswlslsrvncsqflglcalpgckfkdvrrnvqkdteelkscgiqdifvfctrg
elskyrvpnlldlyqqcgiithhhpiadggtpdiascceimeelttclknyrktlihsyg
glgrsclvaaclllylsdtispeqaidslrdlrgsgaiqtikqynylhefrdklaahl

Timeline for d1fpzd_:

• d1fpzd_ first appeared in SCOP 1.57
  
• d1fpzd_ appears in SCOPe 2.04
  
• d1fpzd_ appears in SCOPe 2.06
  
• d1fpzd_ appears in the current release, SCOPe 2.08