Lineage for d1f7aa_ (1f7a A:)

  1. Root: SCOPe 2.07
  2. 2352458Class b: All beta proteins [48724] (178 folds)
  3. 2408655Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2408656Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2408657Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2408673Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. 2408922Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (578 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 2409447Domain d1f7aa_: 1f7a A: [59664]
    complexed with act

Details for d1f7aa_

PDB Entry: 1f7a (more details), 2 Å

PDB Description: how does a symmetric dimer recognize an asymmetric substrate? a substrate complex of hiv-1 protease.
PDB Compounds: (A:) Pol polyprotein

SCOPe Domain Sequences for d1f7aa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1f7aa_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtiriggqlkeallntgaddtvleemnlpgkwkpkmiggiggfikvrqyd
qipveicghkaigtvlvgptpvniigrnlltqigctlnf

SCOPe Domain Coordinates for d1f7aa_:

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Timeline for d1f7aa_: