SCOP 1.67: Domain d1elva1: 1elv A:410-668

Lineage for d1elva1 (1elv A:410-668)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (44 proteins)

6. Protein Complement C1S protease, catalytic domain [63789] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63790] (1 PDB entry)

8. Domain d1elva1: 1elv A:410-668 [59454]
   Other proteins in same PDB: d1elva2
   complexed with fuc, nag, nes, so4; mutant

Details for d1elva1

PDB Entry: 1elv, 1.7 Å

PDB Description: crystal structure of the catalytic domain of human complement c1s protease

SCOP Domain Sequences for d1elva1:

Sequence, based on SEQRES records:

>d1elva1 b.47.1.2 (A:410-668) Complement C1S protease, catalytic domain {Human (Homo sapiens)}
cgvprepfeekqriiggsdadiknfpwqvffdnpwaggalineywvltaahvvegnrept
myvgstsvqtsrlakskmltpehvfihpgwkllavpegrtnfdndialvrlkdpvkmgpt
vspiclpgtssdynlmdgdlglisgwgrtekrdravrlkaarlpvaplrkckevkvekpt
adaeayvftpnmicaggekgmdsckgdsggafavqdpndktkfyaaglvswgpqcgtygl
ytrvknyvdwimktmqens

Sequence, based on observed residues (ATOM records):

>d1elva1 b.47.1.2 (A:410-668) Complement C1S protease, catalytic domain {Human (Homo sapiens)}
cgvprepfiiggsdadiknfpwqvffdnpwaggalineywvltaahvvegnreptmyvgs
tsvqkmltpehvfihpgwkllavpegrtnfdndialvrlkdpvkmgptvspiclpgtssd
ynlmdgdlglisgwgrtekrdravrlkaarlpvaplrkckevayvftpnmicaggekgmd
sckgdsggafavqdpndktkfyaaglvswgpqcgtyglytrvknyvdwimktmqens

Timeline for d1elva1:

• d1elva1 first appeared in SCOP 1.57
  
• d1elva1 appears in SCOP 1.65
  
• d1elva1 appears in SCOP 1.69
  
• d1elva1 appears in the current release, SCOPe 2.08