SCOP 1.75: Domain d1e6wb_: 1e6w B:

Lineage for d1e6wb_ (1e6w B:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Type II 3-hydroxyacyl-CoA dehydrogenase [63933] (3 species)

7. Species Rat (Rattus norvegicus) [TaxId:10116] [63934] (3 PDB entries)

8. Domain d1e6wb_: 1e6w B: [59327]

Details for d1e6wb_

PDB Entry: 1e6w, 1.7 Å

PDB Description: rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and estradiol

PDB Compounds: (B:) short chain 3-hydroxyacyl-coa dehydrogenase

SCOP Domain Sequences for d1e6wb_:

Sequence, based on SEQRES records:

>d1e6wb_ c.2.1.2 (B:) Type II 3-hydroxyacyl-CoA dehydrogenase {Rat (Rattus norvegicus) [TaxId: 10116]}
svkglvavitggasglglstakrlvgqgatavlldvpnsegeteakklggncifapanvt
sekevqaaltlakekfgridvavncagiavaiktyhekknqvhtledfqrvinvnligtf
nvirlvagvmgqnepdqggqrgviintasvaafegqvgqaaysaskggivgmtlpiardl
apigirvvtiapglfatpllttlpdkvrnflasqvpfpsrlgdpaeyahlvqmvienpfl
ngevirldgairmqp

Sequence, based on observed residues (ATOM records):

>d1e6wb_ c.2.1.2 (B:) Type II 3-hydroxyacyl-CoA dehydrogenase {Rat (Rattus norvegicus) [TaxId: 10116]}
svkglvavitggasglglstakrlvgqgatavlldvpnsegeteakklggncifapanvt
sekevqaaltlakekfgridvavncagiavaiktyhekknqvhtledfqrvinvnligtf
nvirlvagvmgqnepdqggqrgviintasvaafegqvgqaaysaskggivgmtlpiardl
apigirvvtiapglfatplltflasqvpfpsrlgdpaeyahlvqmvienpflngevirld
gairmqp

Timeline for d1e6wb_:

• d1e6wb_ first appeared in SCOP 1.57
  
• d1e6wb_ appears in SCOP 1.73
  
• d1e6wb_ appears in SCOPe 2.01
  
• d1e6wb_ appears in the current release, SCOPe 2.08