SCOPe 2.08: Domain d1e3wa_: 1e3w A:

Lineage for d1e3wa_ (1e3w A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein Type II 3-hydroxyacyl-CoA dehydrogenase [63933] (3 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [63934] (3 PDB entries)

8. Domain d1e3wa_: 1e3w A: [59207]
   CASP4
   complexed with aae, nad, so4, trs

Details for d1e3wa_

PDB Entry: 1e3w, 2 Å

PDB Description: rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and 3-keto butyrate

PDB Compounds: (A:) short chain 3-hydroxyacyl-coa dehydrogenase

SCOPe Domain Sequences for d1e3wa_:

Sequence, based on SEQRES records:

>d1e3wa_ c.2.1.2 (A:) Type II 3-hydroxyacyl-CoA dehydrogenase {Norway rat (Rattus norvegicus) [TaxId: 10116]}
svkglvavitggasglglstakrlvgqgatavlldvpnsegeteakklggncifapanvt
sekevqaaltlakekfgridvavncagiavaiktyhekknqvhtledfqrvinvnligtf
nvirlvagvmgqnepdqggqrgviintasvaafegqvgqaaysaskggivgmtlpiardl
apigirvvtiapglfatpllttlpdtvrnflasqvpfpsrlgdpaeyahlvqmvienpfl
ngevirldgairmqp

Sequence, based on observed residues (ATOM records):

>d1e3wa_ c.2.1.2 (A:) Type II 3-hydroxyacyl-CoA dehydrogenase {Norway rat (Rattus norvegicus) [TaxId: 10116]}
svkglvavitggasglglstakrlvgqgatavlldvpnsegeteakklggncifapanvt
sekevqaaltlakekfgridvavncagiavaiktyhekknqvhtledfqrvinvnligtf
nvirlvagvmgqnepdqggqrgviintasvaafegqvgqaaysaskggivgmtlpiardl
apigirvvtiapglfatpllttvrnflasqvpfpsrlgdpaeyahlvqmvienpflngev
irldgairmqp

Timeline for d1e3wa_:

• d1e3wa_ first appeared in SCOP 1.57
  
• d1e3wa_ appears in SCOPe 2.07