SCOPe 2.08: Domain d1e3cp_: 1e3c P:

Lineage for d1e3cp_ (1e3c P:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.76: Alkaline phosphatase-like [53648] (1 superfamily)
   core:3 layers: a/b/a; mixed beta-sheet of 8 strands, order 43516728, strand 7 is antiparallel to the rest

4. Superfamily c.76.1: Alkaline phosphatase-like [53649] (6 families)

5. Family c.76.1.2: Arylsulfatase [53653] (4 proteins)
   includes additional C-terminal alpha+beta (sub)domain

6. Protein Arylsulfatase A [53654] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53655] (7 PDB entries)

8. Domain d1e3cp_: 1e3c P: [59187]
   complexed with mg; mutant

Details for d1e3cp_

PDB Entry: 1e3c, 2.65 Å

PDB Description: crystal structure of an arylsulfatase a mutant c69s soaked in synthetic substrate

PDB Compounds: (P:) arylsulfatase a

SCOPe Domain Sequences for d1e3cp_:

Sequence, based on SEQRES records:

>d1e3cp_ c.76.1.2 (P:) Arylsulfatase A {Human (Homo sapiens) [TaxId: 9606]}
rppnivlifaddlgygdlgcyghpssttpnldqlaagglrftdfyvpvslstpsraallt
grlpvrmgmypgvlvpssrgglpleevtvaevlaargyltgmagkwhlgvgpegaflpph
qgfhrflgipyshdqgpcqnltcfppatpcdggcdqglvpipllanlsveaqppwlpgle
arymafahdlmadaqredrpfflyyashhthypqfsgqsfaersgrgpfgdslmeldaav
gtlmtaigdlglleetlviftadngpetmrmsrggcsgllrcgkgttyeggvrepalafw
pghiapgvthelassldllptlaalagaplpnvtldgfdlsplllgtgksprqslffyps
ypdevrgvfavrtgkykahfftqgsahsdttadpachasssltaheppllydlskdpgen
ynllggvagatpevlqalkqlqllkaqldaavtfgpsqvargedpalqicchpgctprpa
cchcp

Sequence, based on observed residues (ATOM records):

>d1e3cp_ c.76.1.2 (P:) Arylsulfatase A {Human (Homo sapiens) [TaxId: 9606]}
rppnivlifaddlgygdlgcyghpssttpnldqlaagglrftdfyvpvslstpsraallt
grlpvrmgmypgvlvpssrgglpleevtvaevlaargyltgmagkwhlgvgpegaflpph
qgfhrflgipyshdqgpcqnltcfppatpcdggcdqglvpipllanlsveaqppwlpgle
arymafahdlmadaqredrpfflyyashhthypqfsgqsfaersgrgpfgdslmeldaav
gtlmtaigdlglleetlviftadngpetmrmsrggcsgllrcgkgttyeggvrepalafw
pghiapgvthelassldllptlaalagaplpnvtldgfdlsplllgtgksprqslffyps
ypdevrgvfavrtgkykahfftqgsahsdttadpachasssltaheppllydlskdpgen
ynllgatpevlqalkqlqllkaqldaavtfgpsqvargedpalqicchpgctprpacchc
p

Timeline for d1e3cp_:

• d1e3cp_ first appeared in SCOP 1.57
  
• d1e3cp_ appears in SCOPe 2.07