SCOP 1.71: Domain d1e2pb_: 1e2p B:

Lineage for d1e2pb_ (1e2p B:)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (23 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (18 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidine kinase [52552] (3 species)
   contains insert all-alpha subdomain, res. 251-322

7. Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (22 PDB entries)

8. Domain d1e2pb_: 1e2p B: [59171]
   complexed with ccv, so4

Details for d1e2pb_

PDB Entry: 1e2p, 2.5 Å

PDB Description: thymidine kinase, dhbt

SCOP Domain Sequences for d1e2pb_:

Sequence, based on SEQRES records:

>d1e2pb_ c.37.1.1 (B:) Thymidine kinase {Herpes simplex virus type 1, different strains}
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhp
iaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpge
rldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphig
dtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlts
gmvqthvttpgsipticdlartfaremge

Sequence, based on observed residues (ATOM records):

>d1e2pb_ c.37.1.1 (B:) Thymidine kinase {Herpes simplex virus type 1, different strains}
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsppaltlifdrhpiaal
lcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrldlamlaai
rrvygllantvrylqcggswredwgqlsgpqsnagprphigdtlftlfrapellapngdl
ynvfawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdl
artfaremge

Timeline for d1e2pb_:

• d1e2pb_ first appeared in SCOP 1.57
  
• d1e2pb_ appears in SCOP 1.69
  
• d1e2pb_ appears in SCOP 1.73
  
• d1e2pb_ appears in the current release, SCOPe 2.08