SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Class j: Peptides

  1. Root: SCOPe 2.05
  2. 1973804Class j: Peptides [58231] (129 folds)

Folds:

  1. 1973805j.1: Membrane ion channel-forming peptide antibiotics containing D-aminoacids [58232] (1 superfamily)
  2. 1973887j.2: Lantibiotic peptides [58243] (1 superfamily)
    peptide antibiotic
  3. 1973909j.3: Antimicrobial beta-hairpin [58251] (1 superfamily)
    contains beta-hairpin crosslinked by disulfide bridge(s)
  4. 1973957j.4: Antimicrobial helix [58268] (1 superfamily)
    antibiotic peptide
  5. 1974009j.5: Macrocyclic bacteriocins [58278] (1 superfamily)
    macrocyclic antimicrobial peptide; bacteriocin
  6. 1974023j.6: Peptide hormones [58283] (1 superfamily)
    contains one alpha-helix
  7. 1974122j.7: delta toxin-like [58307] (3 superfamilies)
    single alpha helix
  8. 1974148j.8: PSP1-like [58312] (1 superfamily)
  9. 1974172j.9: Arg-rich RNA binding peptides [58321] (7 superfamilies)
  10. 1974266j.10: DNA-binding domains of HMG-I(Y) [58348] (1 superfamily)
  11. 1974275j.11: VPR protein fragments [58353] (1 superfamily)
  12. 1974293j.12: Inactivation gate of potassium and sodium channels [58358] (1 superfamily)
  13. 1974312j.13: Coagulation factor VIII, membrane-binding peptide [58368] (1 superfamily)
  14. 1974319j.14: Phosphocholine cytidylyltransferase membrane-binding peptides [58373] (1 superfamily)
  15. 1974326j.15: Parathyroid hormone fragments (residues between 1 and 39) [58378] (1 superfamily)
  16. 1974351j.16: Corticotropin releasing hormone [58384] (1 superfamily)
  17. 1974364j.17: Liposaccharide-binding protein CAP18 (residues 106-137) [58389] (1 superfamily)
  18. 1974370j.18: Polymorphic antigen SPAM-H1 (residues 90-127) [58394] (1 superfamily)
  19. 1974376j.19: Insect toxins [58399] (1 superfamily)
  20. 1974391j.20: Tertiapin [58404] (1 superfamily)
    small disulfide-rich peptide
  21. 1974397j.21: Antifreeze polypeptide HPLC-6 [58409] (1 superfamily)
  22. 1974407j.22: Troponin I fragments [58414] (1 superfamily)
  23. j.23: Pilin fragments [58420] (1 superfamily)
  24. 1974434j.24: RP71935 [58427] (1 superfamily)
  25. 1974441j.25: Atrial natriuretic peptide [58432] (1 superfamily)
  26. j.26: Compstatin [58437] (1 superfamily)
  27. j.27: Membrane-bound antimicrobial peptides [58442] (1 superfamily)
  28. 1974466j.28: Endothelin-like [58449] (1 superfamily)
    small disulfide-rich
  29. j.29: Heat-stable enterotoxin (HSE) [58457] (1 superfamily)
  30. 1974496j.30: Conotoxins [58464] (1 superfamily)
    disulfide-rich fold
  31. 1974586j.31: Conantokin [58494] (1 superfamily)
  32. j.32: Contryphan-R [58502] (1 superfamily)
  33. 1974609j.33: Kappa-hefutoxin-like [58507] (2 superfamilies)
    hairpin of two short helices crosslinked with two disulfides
  34. j.34: Bradykinin [58512] (1 superfamily)
  35. 1974629j.35: Transmembrane helical fragments [58517] (1 superfamily)
  36. 1974778j.36: Topogenic peptides [58555] (4 superfamilies)
  37. 1974799j.37: Phospholamban fragments [58568] (1 superfamily)
  38. j.38: Fragments of bowman-birk inhibitor [58574] (1 superfamily)
  39. 1974818j.39: Fragments of apolipoproteins [58579] (1 superfamily)
  40. 1974848j.40: Transactivation protein TAT [58593] (1 superfamily)
  41. 1974860j.41: Proline pipe [58599] (1 superfamily)
  42. 1974866j.42: Amyloid peptides [58604] (1 superfamily)
  43. 1974896j.43: Gelsolin fragment (residues 150-169) [58609] (1 superfamily)
  44. j.44: Acetylcholine receptor fragment (residues alpha 67-76) [58614] (1 superfamily)
  45. 1974909j.45: Thrombomodulin EGF domain fragment (residues 409-426) [58619] (1 superfamily)
  46. 1974917j.47: Capsid protein major homology region peptide analog [58629] (1 superfamily)
  47. 1974925j.48: CD4 and CD8 receptor regions [58635] (1 superfamily)
  48. 1974935j.49: Heparin binding site of non collagenous domain I (nc1) of collagen facit xiv [58640] (1 superfamily)
  49. 1974942j.50: GroES fragments [58645] (1 superfamily)
  50. 1974952j.51: cAMP and cGMP phosphodiesterase (PDE) fragments [58650] (1 superfamily)
  51. 1974961j.52: HIV-1 Nef protein fragments [58657] (1 superfamily)
  52. 1974969j.53: HIV-1 envelope gp120 protein fragments [58662] (1 superfamily)
  53. 1974981j.54: Hepatitis C virus N-terminal capsid protein fragment 2-45 [58667] (1 superfamily)
  54. 1974987j.55: P27(KIP1) fragment 22-106 [58672] (1 superfamily)
  55. j.56: Transducin alpha-1 subunit rhodopsin binding domain (res. 340-350) [58677] (1 superfamily)
  56. j.57: alpha-lactalbumin peptide model [58682] (1 superfamily)
  57. 1975006j.58: Coat protein-binding domain of bacteriophage P22 scaffolding protein [58687] (1 superfamily)
  58. j.59: Immunoreceptor tyrosine kinase activation motif, ITAM [58692] (1 superfamily)
  59. 1975019j.60: Integrin fragments [58697] (1 superfamily)
  60. 1975042j.61: Human glutathione reductase (HGR) inhibitor [58702] (1 superfamily)
  61. j.62: Small subunit C-terminal inhibitory peptide of ribonucleotide reductase [58707] (1 superfamily)
  62. j.63: Histone H3 C-terminal fragment 130-135 [58712] (1 superfamily)
  63. 1975064j.64: Smad-binding domain of Sara [58717] (1 superfamily)
  64. 1975072j.65: Peptide derived from p-21 activated kinase [58722] (1 superfamily)
  65. 1975080j.66: pak1 autoregulatory domain [58728] (1 superfamily)
  66. 1975087j.67: Translocated intimin receptor (tir) intimin-binding domain [58733] (1 superfamily)
  67. 1975093j.68: Fragments of the L-type calcium channel alpha subunit Cav.1 (dihydropyridine receptor) [58738] (1 superfamily)
  68. 1975107j.69: Tumor suppressor p53 fragments [58743] (1 superfamily)
  69. j.70: FxFG nucleoporin repeats [58748] (1 superfamily)
  70. 1975125j.71: beta-Catenine bound non-globular protein regions [58753] (1 superfamily)
  71. j.73: VMIP-II fragment [58763] (1 superfamily)
  72. j.74: Papillomavirus e6-interacting peptide of e6ap [58768] (1 superfamily)
  73. 1975156j.75: Isolated insulin B-chain [58773] (1 superfamily)
  74. j.76: Ubiquitin fragments [58778] (1 superfamily)
  75. 1975230j.77: alpha-helical hairpin of p8mtcp1 [58783] (1 superfamily)
  76. 1975236j.78: C-terminal fragment of thermolysin [63387] (1 superfamily)
  77. 1975243j.79: Influenza hemagglutinin fragments [64631] (1 superfamily)
  78. 1975253j.80: Syndecan-4 cytoplasmic domain [64638] (1 superfamily)
  79. 1975262j.81: Pituitary adenylate cyclase activating polypeptide, pacap21 [64643] (1 superfamily)
  80. 1975268j.82: Cholecystokinin receptor fragments [64648] (1 superfamily)
  81. j.83: Trypsin inhibitor SFTIf-1 [64653] (1 superfamily)
  82. 1975284j.84: Ribosomal protein L10 [64658] (1 superfamily)
  83. 1975331j.85: HIV-1 gp41 fragments [70010] (1 superfamily)
  84. 1975356j.86: Actin-binding peptides [70017] (1 superfamily)
  85. 1975365j.87: Rack1 interaction site of the CAMP-specific phosphodiesterase pde4d5. [70022] (1 superfamily)
  86. 1975371j.88: Prepeptide of 5-ALAS [70027] (1 superfamily)
  87. 1975378j.89: the cytoplasmic N-terminus of the bk beta-subunit kcnmb2 [70032] (1 superfamily)
  88. 1975384j.90: Prion protein fragments [70037] (1 superfamily)
  89. 1975397j.91: Tumor suppressor protein p19-ARF fragment [70042] (1 superfamily)
  90. j.92: Antennapedia homeodomain fragments [70047] (1 superfamily)
  91. 1975412j.93: Sheep myeloid antimicrobial peptide SMAP29 based peptides [75751] (1 superfamily)
  92. 1975421j.94: alpha-2a adrenergic receptor pepride t3-i2 [75756] (1 superfamily)
  93. 1975430j.95: Catestatin fragment from chromogranin A [75761] (1 superfamily)
  94. 1975437j.96: Transactivation domain [81275] (1 superfamily)
  95. 1975450j.97: BRCA2 BRC4 repeat [82985] (1 superfamily)
  96. j.98: Bhpbr3, the Baff-binding loop of br3 embedded in a beta-hairpin peptide [82992] (1 superfamily)
  97. 1975462j.99: N-terminal fragment of gastric H/K-ATPase [82997] (1 superfamily)
  98. 1975469j.100: Barstar fragment [83002] (1 superfamily)
  99. j.101: Cannabinoid receptor 1 (CB1) fragment [83007] (1 superfamily)
  100. j.102: Angiotensin [90269] (1 superfamily)
  101. j.103: Transducin gamma-t1 subunit rhodopsin bound fragment (res. 60-71) [90290] (1 superfamily)
  102. 1975497j.104: TBP-binding domain of the transcription factor IIIb Brf1 subunit [90297] (1 superfamily)
  103. 1975506j.105: Ubiquitin interacting motif (UIM) [90302] (1 superfamily)
  104. 1975519j.106: Leucocin-like bacteriocin [100898] (1 superfamily)
    consists of a conserved, disulfide-containing N-terminal region (forming a beta-sheet) and a C-terminal helix
  105. 1975536j.107: Penaeidin-3a [103726] (1 superfamily)
  106. 1975542j.108: Proto-oncogene tyrosine-protein kinase lck CD4/CD8 interacting region [103748] (1 superfamily)
  107. j.109: Metal-binding peptide from MerP [103758] (1 superfamily)
  108. j.110: Marinostatin, MstI [103763] (1 superfamily)
  109. j.111: Cross-reactive peptides from 60S acidic ribosomal protein p2 [103768] (1 superfamily)
  110. 1975569j.112: Nuclear receptor coactivator Src-1 [100901] (1 superfamily)
  111. 1975578j.113: NTR, cyclotide processing element [111516] (1 superfamily)
  112. 1975587j.114: HMG-box transcription factor 1 fragments [111523] (1 superfamily)
  113. j.115: MAD protein fragments [111528] (1 superfamily)
  114. 1975599j.116: Fragments of TNF receptors [111533] (1 superfamily)
  115. 1975605j.117: Ezrin-radixin-moesin binding phosphoprotein 50 (ebp50) fragments [111538] (1 superfamily)
  116. 1975611j.118: Ribosomal protein L34p [144320] (1 superfamily)
    non-globular, mainly alpha-helical
  117. 1975647j.119: Retinoblastoma-associated protein RB1 fragments [144325] (1 superfamily)
  118. 1975653j.120: Genome linked protein vpg [144330] (1 superfamily)
  119. 1975660j.121: Programmed cell death protein 5 fragments [144335] (1 superfamily)
  120. 1975666j.122: Ribosomal protein S21p [161307] (1 superfamily)
    non-globular, mainly alpha-helical
  121. j.123: Transforming growth factor alpha fragments [254105] (1 superfamily)
  122. j.124: YefM fragments [254106] (1 superfamily)
  123. j.125: IAP fragments [254107] (1 superfamily)
  124. 1975714j.126: cAMP-dependent protein kinase inhibitor [254108] (1 superfamily)
  125. 1975725j.127: Complement system alpha-prime linker [254110] (1 superfamily)
  126. 1975735j.128: Complement system anchor region [254111] (1 superfamily)
  127. 1975745j.129: DNMT1 CXXC-BAH1 linker domain-like [267592] (1 superfamily)
  128. j.130: STM1 N-terminal region [267593] (1 superfamily)
    Pfam PF09598; elongated structure binds ribosome in mRNA entry tunnel and elsewhere (PubMed 22096102)
  129. 1975760j.131: Filamin fragments [267594] (1 superfamily)

More info for Class j: Peptides

Timeline for Class j: Peptides: