Lineage for Fold h.4: Antiparallel coiled-coil

  1. Root: SCOP 1.73
  2. 752207Class h: Coiled coil proteins [57942] (7 folds)
  3. 753527Fold h.4: Antiparallel coiled-coil [58086] (15 superfamilies)
    this is not a true fold; contains at least two very long antiparallel helices

Superfamilies:

  1. 753528h.4.1: Variant surface glycoprotein (N-terminal domain) [58087] (1 family) (S)
  2. 753536h.4.2: Clostridium neurotoxins, "coiled-coil" domain [58091] (1 family) (S)
  3. 753556h.4.3: Colicin Ia, N-terminal domain [58096] (1 family) (S)
  4. 753561h.4.4: Hemolysin E (HlyE, ClyA, SheA) [58100] (1 family) (S)
  5. 753566h.4.5: Methyl-accepting chemotaxis protein (MCP) signaling domain [58104] (1 family) (S)
  6. 753576h.4.6: Oligomerization domain of hepatitis delta antigen [58108] (1 family) (S)
  7. 753585h.4.8: F1 ATPase inhibitor, IF1, C-terminal domain [64602] (1 family) (S)
  8. 753596h.4.9: Colicin E3 receptor domain [69985] (1 family) (S)
  9. 753606h.4.10: C-terminal domain of PLC-beta [69989] (1 family) (S)
    left-handed antiparallel coiled-coil; dimerizes with the formation of a 4-helical bundle
  10. 753612h.4.11: Chemotaxis phosphatase CheZ [75708] (1 family) (S)
    dimerizes with the formation of a 4-helical bundle
  11. 753617h.4.12: Rad50 coiled-coil Zn hook [75712] (1 family) (S)
    dimerizes via a CxxC motif in the loop, zinc-hook
  12. 753623h.4.13: Tumor suppressor gene product Apc [82931] (1 family) (S)
  13. 753628h.4.15: Proline/betaine transporter ProP, C-terminal cytoplasmic domain [103661] (1 family) (S)
  14. 753634h.4.16: Fzo-like conserved region [111479] (1 family) (S)
    antiparallel coiled-coil in the crystals
  15. 753639h.4.17: occludin/ELL-like [144292] (1 family) (S)
    antiparallel hairpin with a kinked second helix; similar to the N-terminal structure of the thermostable carboxypeptidase 1 (scop_pr 82731)

More info for Fold h.4: Antiparallel coiled-coil

Timeline for Fold h.4: Antiparallel coiled-coil: