SCOP 1.65: Family h.1.15.1: SNARE fusion complex

Lineage for Family h.1.15.1: SNARE fusion complex

1. Root: SCOP 1.65

2. Class h: Coiled coil proteins [57942] (6 folds)

3. Fold h.1: Parallel coiled-coil [57943] (26 superfamilies)
   this is not a true fold; includes oligomers of shorter identical helices

4. Superfamily h.1.15: SNARE fusion complex [58038] (1 family)
   tetrameric parallel coiled coil

5. Family h.1.15.1: SNARE fusion complex [58039] (10 proteins)

Proteins:

1. Complexin [88921] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [88922] (1 PDB entry)

2. Endobrevin [88906] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [88907] (1 PDB entry)

3. Synaphin [88923] (1 species)

   • Species Longfin squid (Loligo pealei) [TaxId:6621] [88924] (1 PDB entry)

4. Synaptobrevin [88903] (2 species)

   1. Species Longfin squid (Loligo pealei) [TaxId:6621] [88905] (1 PDB entry)

   2. Species Rat (Rattus norvegicus) [TaxId:10116] [88904] (3 PDB entries)

5. Synaptosomal-assosiated protein SNAP-23 [90240] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [90241] (1 PDB entry)

6. Synaptosomal-assosiated protein SNAP-25 [88915] (3 species)
   provides up to two different helical regions to synaptic fusion complexes

   1. Species Human (Homo sapiens) [TaxId:9606] [88917] (1 PDB entry)
      identical sequences to rat species

   2. Species Longfin squid (Loligo pealei) [TaxId:6621] [88918] (1 PDB entry)

   3. Species Rat (Rattus norvegicus) [TaxId:10116] [88916] (3 PDB entries)
      identical sequences to human species

7. Syntaxin 1A [88908] (2 species)

   1. Species Longfin squid (Loligo pealei) [TaxId:6621] [88910] (1 PDB entry)

   2. Species Rat (Rattus norvegicus) [TaxId:10116] [88909] (5 PDB entries)
      a globular structure of a larger fragment containing this region is available; (1dn1), chain B or (d1dn1b_)_

8. Syntaxin 7 [88911] (1 species)
   complex with endobrevin, VTI1B and syntaxin 8

   • Species Mouse (Mus musculus) [TaxId:10090] [88912] (1 PDB entry)

9. Syntaxin 8 [88913] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [88914] (1 PDB entry)

10. Vesicle ransport v-SNARE protein VTI1b [88919] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [88920] (1 PDB entry)

More info for Family h.1.15.1: SNARE fusion complex

Timeline for Family h.1.15.1: SNARE fusion complex:

• Family h.1.15.1: SNARE fusion complex first appeared (with stable ids) in SCOP 1.55, called Family h.1.15.1: Neuronal synaptic fusion complex
  
• Family h.1.15.1: SNARE fusion complex was called Family h.1.15.1: Neuronal synaptic fusion complex in SCOP 1.63
  
• Family h.1.15.1: SNARE fusion complex appears in SCOP 1.67
  
• Family h.1.15.1: SNARE fusion complex appears in the current release, SCOPe 2.08