SCOPe 2.03: Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat

Lineage for Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat

1. Root: SCOPe 2.03

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.52: Inhibitor of apoptosis (IAP) repeat [57923] (1 superfamily)
   metal(zinc)-bound alpha+beta fold

4. Superfamily g.52.1: Inhibitor of apoptosis (IAP) repeat [57924] (2 families)

5. Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat [57925] (7 proteins)

Proteins:

1. 2MIHB/C-IAP-1 [57926] (1 species)
   baculoviral inhibitor of apoptosis

   • Species Human (Homo sapiens) [TaxId:9606] [57927] (4 PDB entries)

2. Anti-apoptotic protein survivin [57930] (2 species)
   contains a long alpha-helix after the common fold

   1. Species Human (Homo sapiens) [TaxId:9606] [57931] (9 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [82925] (1 PDB entry)

3. BIR domains of DIAP1 [69974] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [69975] (6 PDB entries)

4. BIR domains of XIAP [57928] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [57929] (13 PDB entries)
     Uniprot P98170 241-356

5. BIR-containing protein 7 (ML-IAP, livin) [103630] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [103631] (6 PDB entries)
     Uniprot Q96CA5 78-159

6. BIR-containing protein 8 [118349] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [118350] (2 PDB entries)
     Uniprot Q96P09 1-84

7. automated matches [190700] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [187840] (21 PDB entries)

More info for Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat

Timeline for Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat:

• Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat first appeared (with stable ids) in SCOP 1.55
  
• Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat appears in SCOPe 2.02
  
• Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat appears in SCOPe 2.04
  
• Family g.52.1.1: Inhibitor of apoptosis (IAP) repeat appears in the current release, SCOPe 2.08