SCOP 1.71: Family g.50.1.1: FYVE, a phosphatidylinositol-3-phosphate binding domain

Lineage for Family g.50.1.1: FYVE, a phosphatidylinositol-3-phosphate binding domain

1. Root: SCOP 1.71

2. Class g: Small proteins [56992] (79 folds)

3. Fold g.50: FYVE/PHD zinc finger [57902] (1 superfamily)
   dimetal(zinc)-bound alpha+beta fold

4. Superfamily g.50.1: FYVE/PHD zinc finger [57903] (3 families)

5. Family g.50.1.1: FYVE, a phosphatidylinositol-3-phosphate binding domain [57904] (6 proteins)

Proteins:

1. Eea1 [64583] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [64584] (3 PDB entries)

2. Effector domain of rabphilin-3a [57909] (1 species)
   contains additional N-terminal long alpha-helix

   • Species Rat (Rattus norvegicus) [TaxId:10116] [57910] (1 PDB entry)

3. Hrs [57907] (1 species)
   protein involved in membrane trafficking and signal transduction

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [57908] (1 PDB entry)

4. Rififylin (FYVE-RING finger protein Sakura) [118326] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [118327] (1 PDB entry)

5. vps27p protein [57905] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [57906] (1 PDB entry)

6. Zinc finger FYVE domain containing protein 19 [118324] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [118325] (1 PDB entry)

More info for Family g.50.1.1: FYVE, a phosphatidylinositol-3-phosphate binding domain

Timeline for Family g.50.1.1: FYVE, a phosphatidylinositol-3-phosphate binding domain:

• Family g.50.1.1: FYVE, a phosphatidylinositol-3-phosphate binding domain first appeared (with stable ids) in SCOP 1.55
  
• Family g.50.1.1: FYVE, a phosphatidylinositol-3-phosphate binding domain appears in SCOP 1.69
  
• Family g.50.1.1: FYVE, a phosphatidylinositol-3-phosphate binding domain appears in SCOP 1.73
  
• Family g.50.1.1: FYVE, a phosphatidylinositol-3-phosphate binding domain appears in the current release, SCOPe 2.08