SCOPe 2.02: Family g.39.1.3: LIM domain

Lineage for Family g.39.1.3: LIM domain

1. Root: SCOPe 2.02

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.39: Glucocorticoid receptor-like (DNA-binding domain) [57715] (1 superfamily)
   alpha+beta metal(zinc)-bound fold

4. Superfamily g.39.1: Glucocorticoid receptor-like (DNA-binding domain) [57716] (19 families)

5. Family g.39.1.3: LIM domain [57736] (18 proteins)
   duplication: contains two (sub)domains of this fold

Proteins:

1. Actin-binding LIM protein 2, abLIM2 [111441] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [111442] (2 PDB entries)
     Uniprot Q6H8Q1 73-140, 212-271

2. Actin-binding LIM protein 3, abLIM-3 [144179] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [144180] (1 PDB entry)
     Uniprot O94929 141-176! Uniprot O94929 177-207

3. Cysteine-rich (intestinal) protein, CRP, CRIP [57737] (4 species)

   1. Species Chicken (Gallus gallus) [TaxId:9031] [57738] (2 PDB entries)

   2. Species Human (Homo sapiens) [TaxId:9606] [144160] (1 PDB entry)
      Uniprot P52943 1-30! Uniprot P52943 31-63
      CRP2

   3. Species Japanese quail (Coturnix coturnix japonica), CRP2 [TaxId:93934] [57739] (4 PDB entries)

   4. Species Rat (Rattus rattus) [TaxId:10117] [57740] (1 PDB entry)

4. Eplin, LIMA1 [144165] (1 species)
   Epithelial protein lost in neoplasm

   • Species Human (Homo sapiens) [TaxId:9606] [144166] (1 PDB entry)
     Uniprot Q9UHB6 381-417! Uniprot Q9UHB6 416-457

5. Four and a half LIM domains 3, FHL3 [144167] (1 species)
   Skeletal muscle lim-protein 2

   • Species Human (Homo sapiens) [TaxId:9606] [144168] (2 PDB entries)
     Uniprot Q13643 127-159! Uniprot Q13643 152-186! Uniprot Q13643 187-218! Uniprot Q13643 98-126

6. Four and a half LIM domains protein 1, FHL-1 [144163] (1 species)
   Skeletal muscle lim-protein 1

   • Species Human (Homo sapiens) [TaxId:9606] [144164] (3 PDB entries)
     Uniprot Q13642 128-159! Uniprot Q13642 161-185! Uniprot Q13642 186-216! Uniprot Q13642 39-66! Uniprot Q13642 67-97! Uniprot Q13642 90-127! Uniprot Q13642 98-127

7. Four and a half LIM domains protein 2, FHL2 [144161] (1 species)
   Skeletal muscle lim-protein 3

   • Species Human (Homo sapiens) [TaxId:9606] [144162] (3 PDB entries)
     Uniprot Q14192 128-159! Uniprot Q14192 162-186! Uniprot Q14192 187-218! Uniprot Q14192 221-249! Uniprot Q14192 250-279! Uniprot Q14192 98-127

8. Four and a half LIM domains protein 5, FHL-5 [144181] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [144182] (1 PDB entry)
     Uniprot Q5TD97 222-250! Uniprot Q5TD97 251-284

9. Leupaxin [144175] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [144176] (1 PDB entry)
     Uniprot O60711 260-295! Uniprot O60711 296-327

10. Lim domain kinase 2 [144183] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [144184] (1 PDB entry)
      Uniprot P53671 62-95! Uniprot P53671 96-129

11. LIM only 4 (Lmo4) [90205] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [90206] (2 PDB entries)
      Uniprot P61969 19-152

12. Nedd9 interacting protein with calponin homology, NICAL (MICAL1) [144173] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [144174] (1 PDB entry)
      Uniprot Q8TDZ2 687-722! Uniprot Q8TDZ2 723-755

13. PDZ and LIM domain protein 1 Elfin [144171] (1 species)
    C-terminal LIM domain protein 1

    • Species Human (Homo sapiens) [TaxId:9606] [144172] (1 PDB entry)
      Uniprot O00151 249-279! Uniprot O00151 280-314

14. PDZ and LIM domain protein 3, PDLIM3 [144185] (1 species)
    Alpha-actinin-2-associated LIM protein

    • Species Mouse (Mus musculus) [TaxId:10090] [144186] (1 PDB entry)
      Uniprot O70209 270-301! Uniprot O70209 271-301

15. PDZ and LIM domain protein 5, Enigma [144169] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [144170] (1 PDB entry)
      Uniprot Q96HC4 400-444! Uniprot Q96HC4 445-476

16. Pinch (particularly interesting new Cys-His) protein [57741] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [57742] (5 PDB entries)

17. Rhombotin-2 (Lmo2) [90203] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [90204] (1 PDB entry)

18. Thyroid receptor interacting protein 6, TRIP6 [144177] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [144178] (2 PDB entries)
      Uniprot Q15654 279-305! Uniprot Q15654 306-337! Uniprot Q15654 363-396! Uniprot Q15654 364-396

More info for Family g.39.1.3: LIM domain

Timeline for Family g.39.1.3: LIM domain:

• Family g.39.1.3: LIM domain first appeared (with stable ids) in SCOP 1.55
  
• Family g.39.1.3: LIM domain appears in SCOPe 2.01
  
• Family g.39.1.3: LIM domain appears in SCOPe 2.03
  
• Family g.39.1.3: LIM domain appears in the current release, SCOPe 2.08