SCOP 1.67: Family g.39.1.2: Nuclear receptor

Lineage for Family g.39.1.2: Nuclear receptor

1. Root: SCOP 1.67

2. Class g: Small proteins [56992] (72 folds)

3. Fold g.39: Glucocorticoid receptor-like (DNA-binding domain) [57715] (1 superfamily)
   alpha+beta metal(zinc)-bound fold

4. Superfamily g.39.1: Glucocorticoid receptor-like (DNA-binding domain) [57716] (11 families)

5. Family g.39.1.2: Nuclear receptor [57721] (11 proteins)
   duplication: two zinc-binding motifs

Proteins:

1. Ecdysone receptor DNA-binding domain [103601] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [103602] (2 PDB entries)

2. Estrogen receptor DNA-binding domain [57728] (1 species)

   • Species Human and chicken (Homo sapiens) and (Gallus gallus) [TaxId:9606] [57729] (2 PDB entries)
     identical sequences

3. Glucocorticoid receptor DNA-binding domain [57730] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [57731] (7 PDB entries)

4. Orphan nuclear receptor NGFI-B DNA-binding domain [57726] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [57727] (1 PDB entry)

5. Orphan nuclear receptor reverb DNA-binding domain [57734] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [57735] (3 PDB entries)

6. Retinoic acid receptor DNA-binding domain [57732] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [57733] (2 PDB entries)

7. Retinoid X receptor (RXR-alpha) DNA-binding domain [57722] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [57723] (5 PDB entries)

8. Steroid hormone receptor Err2 DNA-binding domain [90201] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [90202] (1 PDB entry)

9. Thyroid hormone receptor (TR-beta) DNA-binding domain [57724] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [57725] (1 PDB entry)

10. Ultraspiracle protein [103603] (1 species)

    • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [103604] (1 PDB entry)

11. Vitamin D3 receptor, VDR, DNA-binding domain [75686] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [75687] (3 PDB entries)

More info for Family g.39.1.2: Nuclear receptor

Timeline for Family g.39.1.2: Nuclear receptor:

• Family g.39.1.2: Nuclear receptor first appeared (with stable ids) in SCOP 1.55
  
• Family g.39.1.2: Nuclear receptor appears in SCOP 1.65
  
• Family g.39.1.2: Nuclear receptor appears in SCOP 1.69
  
• Family g.39.1.2: Nuclear receptor appears in the current release, SCOPe 2.08