Lineage for Family g.37.1.1: Classic zinc finger, C2H2

  1. Root: SCOPe 2.05
  2. 1959977Class g: Small proteins [56992] (92 folds)
  3. 1964751Fold g.37: beta-beta-alpha zinc fingers [57666] (1 superfamily)
    simple fold, consisting of the N-terminal beta-hairpin and C-terminal alpha-helical region; each part provides two zinc-coordinating residues with the observed sequences including C2H2, C2HC and CHHC
  4. 1964752Superfamily g.37.1: beta-beta-alpha zinc fingers [57667] (8 families) (S)
  5. 1964753Family g.37.1.1: Classic zinc finger, C2H2 [57668] (31 protein domains)

Protein Domains:

  1. 1964754ADR1 [57675] (1 species)
  2. 1964762Enhancer binding protein [57685] (1 species)
    duplication: consists of two Zn fingers
  3. 1964768Five-finger GLI1 [57683] (1 species)
  4. 1964775GAGA factor [57695] (1 species)
  5. 1964779GLI-Krueppel family member HKR3 [144147] (1 species)
    ZBTB48
  6. 1964785Kruppel-like factor 3, Bklf [103597] (1 species)
  7. 1964790PATZ1 [161152] (1 species)
    Zinc finger protein 278
  8. 1964799SWI5 zinc-finger domains [57681] (1 species)
  9. 1964803Tramtrack protein (two zinc-finger peptide) [57673] (1 species)
  10. 1964809Transactivation domain of cre-bp1/atf-2 [57689] (1 species)
  11. Transcription factor IIIA, TFIIIA [57693] (1 species)
    duplication: consists of 6 fingers
  12. 1964840Transcription factor sp1 [57687] (1 species)
  13. 1964846Transcriptional repressor CTCF [144153] (1 species)
  14. 1964852V(D)J recombination activating protein 1 (RAG1), dimerization domain [57671] (1 species)
  15. 1964855Wilms' tumor protein, WT1 [118269] (1 species)
  16. 1964858XFIN, third domain [57677] (1 species)
  17. 1964861Ying-yang 1 (yy1, zinc finger domain) [57691] (1 species)
    duplication: consists of 4 fingers
  18. 1964867ZFY [57679] (1 species)
  19. 1964874ZIF268 [57669] (1 species)
    duplication: consists of 3 fingers
  20. 1964931Zinc finger and SCAN domain-containing protein 16, ZSCAN16 [144155] (1 species)
    Zinc finger protein 435
  21. 1964935Zinc finger protein 24 [144143] (1 species)
  22. 1964939Zinc finger protein 292, ZNF292 [144133] (1 species)
  23. 1964942Zinc finger protein 295, ZNF295 [118267] (1 species)
  24. 1964947Zinc finger protein 297b [144145] (1 species)
  25. 1964951Zinc finger protein 462, ZNF462 [144137] (1 species)
  26. 1964954Zinc finger protein 512, ZNF512 [144135] (1 species)
  27. 1964958Zinc finger protein 64, ZFP68 [144149] (1 species)
  28. 1964965Zinc finger protein 692, ZNF692 [144139] (1 species)
  29. 1964969Zinc finger protein ZFPM1 (FOG-1) [111434] (1 species)
  30. 1964972Zinc fingers and homeoboxes protein 1, ZHX1 [144141] (1 species)
  31. 1964976automated matches [192458] (2 species)
    not a true protein
    1. 1964977Species Human (Homo sapiens) [TaxId:9606] [161316] (92 PDB entries)
    2. 1965070Species Mouse (Mus musculus) [TaxId:10090] [161315] (1 PDB entry)

More info for Family g.37.1.1: Classic zinc finger, C2H2

Timeline for Family g.37.1.1: Classic zinc finger, C2H2: