SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Fold g.16: Trefoil/Plexin domain-like

  1. Root: SCOPe 2.06
  2. 2229111Class g: Small proteins [56992] (94 folds)
  3. 2232513Fold g.16: Trefoil/Plexin domain-like [57491] (3 superfamilies)
    disulfide-rich fold; common core is alpha+beta with two conserved disulfides


  1. 2232514g.16.1: Trefoil [57492] (1 family) (S)
  2. 2232542g.16.2: Plexin repeat [103575] (1 family) (S)
  3. 2232563g.16.3: Variant surface glycoprotein MITAT 1.2, VSG 221, C-terminal domain [118251] (1 family) (S)
    alpha-beta(2)-alpha; fragment of a larger dimeric protein

More info for Fold g.16: Trefoil/Plexin domain-like

Timeline for Fold g.16: Trefoil/Plexin domain-like: