SCOP 1.65: Family g.15.1.1: Animal Kazal-type inhibitors

Lineage for Family g.15.1.1: Animal Kazal-type inhibitors

1. Root: SCOP 1.65

2. Class g: Small proteins [56992] (66 folds)

3. Fold g.15: Ovomucoid/PCI-1 like inhibitors [57466] (1 superfamily)
   disulphide-rich small alpha+beta fold

4. Superfamily g.15.1: Ovomucoid/PCI-1 like inhibitors [57467] (2 families)
   two families share the same beta-sheet topology but differ in the active-site loop location

5. Family g.15.1.1: Animal Kazal-type inhibitors [57468] (10 proteins)

Proteins:

1. Ascidian trypsin inhibitor [75678] (1 species)

   • Species Sea squirt (Halocynthia roretzi) [TaxId:7729] [75679] (1 PDB entry)

2. Blood-sucking insect-derived tryptase inhibitor [57476] (1 species)
   duplication: contains two domains of this fold

   • Species Bug (Rhodnius prolixus), rhodniin [TaxId:13249] [57477] (2 PDB entries)

3. Dipetalin [75676] (1 species)

   • Species Dipetalogaster maximus, dipetalin [TaxId:72496] [75677] (1 PDB entry)

4. Domain of BM-40/SPARC/osteonectin [57478] (1 species)
   the C-terminal part of FS module

   • Species Human (Homo sapiens) [TaxId:9606] [57479] (2 PDB entries)

5. Domain of follistatin [90166] (1 species)
   the C-terminal part of the heparin-binding module, FS1

   • Species Rat (Rattus norvegicus) [TaxId:10116] [90167] (3 PDB entries)

6. Leech derived tryptase inhibitor (LDTI-C) [57484] (1 species)

   • Species Medicinal leech (Hirudo medicinalis) [TaxId:6421] [57485] (2 PDB entries)

7. Ovomucoid III domain [57469] (3 species)

   1. Species Japanese quail (Coturnix coturnix japonica) [TaxId:93934] [57471] (2 PDB entries)

   2. Species Silver pheasant (Lophura nycthemera) [TaxId:9046] [57472] (4 PDB entries)

   3. Species Turkey (Meleagris gallopavo) [TaxId:9103] [57470] (20 PDB entries)

8. PEC-60 peptide [57482] (1 species)

   • Species Pig (Sus scrofa) [TaxId:9823] [57483] (1 PDB entry)

9. Secretory trypsin inhibitor [57473] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [57474] (3 PDB entries)

   2. Species Pig (Sus scrofa) [TaxId:9823] [57475] (1 PDB entry)

10. Seminal plasma inhibitor IIa [57480] (1 species)

    • Species Cow (Bos taurus) [TaxId:9913] [57481] (2 PDB entries)

More info for Family g.15.1.1: Animal Kazal-type inhibitors

Timeline for Family g.15.1.1: Animal Kazal-type inhibitors:

• Family g.15.1.1: Animal Kazal-type inhibitors first appeared (with stable ids) in SCOP 1.55
  
• Family g.15.1.1: Animal Kazal-type inhibitors appears in SCOP 1.63
  
• Family g.15.1.1: Animal Kazal-type inhibitors is called Family g.68.1.1: Ovomucoid domain III-like in SCOP 1.67
  
• Family g.15.1.1: Animal Kazal-type inhibitors appears in the current release, SCOPe 2.08, called Family g.68.1.1: Ovomucoid domain III-like