SCOPe 2.05: Family g.7.1.1: Snake venom toxins

Lineage for Family g.7.1.1: Snake venom toxins

1. Root: SCOPe 2.05

2. Class g: Small proteins [56992] (92 folds)

3. Fold g.7: Snake toxin-like [57301] (1 superfamily)
   disulfide-rich fold: nearly all-beta

4. Superfamily g.7.1: Snake toxin-like [57302] (4 families)

5. Family g.7.1.1: Snake venom toxins [57303] (28 proteins)
   automatically mapped to Pfam PF00087

Proteins:

1. alpha-Cobratoxin [57318] (3 species)

   1. Species Cobra (Naja siamensis) [TaxId:84476] [57319] (3 PDB entries)

   2. Species Monocled cobra (Naja kaouthia) [TaxId:8649] [189877] (1 PDB entry)

   3. Species Monocled cobra (Naja naja kaouthia) [TaxId:8649] [82899] (2 PDB entries)
      identical sequence to the Naja naja siamensis toxin

2. alpha-Toxin [57344] (2 species)

   1. Species Black mamba (Dendroaspis polylepis polylepis) [TaxId:8620] [57346] (1 PDB entry)

   2. Species Spitting cobra (Naja nigricollis) [TaxId:8654] [57345] (2 PDB entries)

3. Bucain [111404] (1 species)

   • Species Malayan krait (Bungarus candidus) [TaxId:92438] [111405] (2 PDB entries)
     Uniprot P83346

4. Bucandin [57328] (1 species)

   • Species Malayan krait (Bungarus candidus) [TaxId:92438] [57329] (2 PDB entries)

5. Bungarotoxin [57324] (4 species)

   1. Species Many-banded krait (Bungarus multicinctus), Alpha-bungarotoxin [TaxId:8616] [57325] (23 PDB entries)

   2. Species Many-banded krait (Bungarus multicinctus), gamma-bungarotoxin [TaxId:8616] [111403] (1 PDB entry)
      Uniprot Q9YGJ0 22-89

   3. Species Many-banded krait (Bungarus multicinctus), kappa-bungarotoxin [TaxId:8616] [57326] (1 PDB entry)

   4. Species Many-banded krait (Bungarus multicinctus), neuronal bungarotoxin [TaxId:8616] [57327] (1 PDB entry)

6. Candoxin [69949] (1 species)

   • Species Malayan krait (Bungarus candidus) [TaxId:92438] [69950] (1 PDB entry)

7. Cardiotoxin CTX IIB [57332] (1 species)

   • Species Naja mossambica mossambica [TaxId:196380] [57333] (1 PDB entry)

8. Cardiotoxin CTXI [57330] (1 species)

   • Species Taiwan cobra (Naja naja atra) [TaxId:8656] [57331] (1 PDB entry)

9. Cardiotoxin II [57334] (2 species)

   1. Species Central asian cobra (Naja naja oxiana) [TaxId:8657] [57336] (3 PDB entries)

   2. Species Taiwan cobra (Naja naja atra) [TaxId:8656] [57335] (4 PDB entries)

10. Cardiotoxin III [57337] (1 species)

    • Species Taiwan cobra (Naja naja atra) [TaxId:8656] [57338] (6 PDB entries)
      Uniprot P60301 22-81

11. Cardiotoxin IV [57339] (1 species)

    • Species Taiwan cobra (Naja naja atra) [TaxId:8656] [57340] (3 PDB entries)

12. Cardiotoxin V [57316] (1 species)

    • Species Taiwan cobra (Naja naja atra) [TaxId:8656] [57317] (2 PDB entries)

13. Cardiotoxin V4II (Toxin III) [57314] (1 species)

    • Species Naja mossambica mossambica [TaxId:196380] [57315] (1 PDB entry)

14. Cobrotoxin II (ct2) [57341] (2 species)

    1. Species Monocled cobra (Naja kaouthia) [TaxId:8649] [57343] (1 PDB entry)

    2. Species Taiwan cobra (Naja naja atra) [TaxId:8656] [57342] (3 PDB entries)
       Uniprot P60770 22-83

15. Denmotoxin [144107] (1 species)

    • Species Mangrove snake (Boiga dendrophila) [TaxId:46286] [144108] (1 PDB entry)
      Uniprot Q06ZW0 33-111

16. Erabutoxin A [57310] (1 species)

    • Species Broad-banded blue sea snake (Laticauda semifasciata) [TaxId:8631] [57311] (3 PDB entries)

17. Erabutoxin B (also neurotoxin B) [57304] (1 species)

    • Species Sea snake (Laticauda semifasciata) [TaxId:8631] [57305] (7 PDB entries)

18. Fasciculin [57308] (1 species)
    different isoforms

    • Species Green mamba (Dendroaspis angusticeps) [TaxId:8618] [57309] (11 PDB entries)

19. FS2 toxin [57322] (1 species)

    • Species Black mamba (Dendroaspis polylepis polylepis) [TaxId:8620] [57323] (1 PDB entry)

20. gamma-Cardiotoxin [57306] (1 species)

    • Species Snake (Naja nigricollis) [TaxId:8654] [57307] (3 PDB entries)

21. Irditoxin subunit A [144103] (1 species)

    • Species Brown tree snake (Boiga irregularis) [TaxId:92519] [144104] (1 PDB entry)
      Uniprot A0S864 35-109

22. Irditoxin subunit B [144105] (1 species)

    • Species Brown tree snake (Boiga irregularis) [TaxId:92519] [144106] (1 PDB entry)
      Uniprot A0S865 35-111

23. Long neurotoxin 1 (component LSIII) [57320] (1 species)

    • Species Sea snake (Laticauda semifasciata) [TaxId:8631] [57321] (1 PDB entry)

24. Muscarinic toxin [90152] (1 species)
    acetylcholine receptor binding protein

    • Species Green mamba (Dendroaspis angusticeps) [TaxId:8618] [90153] (1 PDB entry)

25. Neurotoxin I [57312] (1 species)

    • Species Snake (Naja naja oxiana) [TaxId:8657] [57313] (2 PDB entries)
      Uniprot P01382

26. Neurotoxin II (Nt2, cobrotoxin B) [57347] (3 species)

    1. Species Central asian cobra (Naja naja oxiana) [TaxId:8657] [57348] (2 PDB entries)

    2. Species Chinese cobra (Naja atra) [TaxId:8656] [103569] (2 PDB entries)
       Uniprot P80958 22-82

    3. Species Monocled cobra (Naja kaouthia) [TaxId:8649] [64550] (1 PDB entry)

27. Toxin B (long neurotoxin) [57349] (1 species)

    • Species King cobra (Ophiophagus hannah) [TaxId:8665] [57350] (2 PDB entries)

28. automated matches [190676] (7 species)
    not a true protein

    1. Species Chinese cobra (Naja atra) [TaxId:8656] [188029] (1 PDB entry)

    2. Species Dendroaspis polylepis [TaxId:8620] [257019] (1 PDB entry)

    3. Species Green mamba (Dendroaspis angusticeps) [TaxId:8618] [197029] (1 PDB entry)

    4. Species Hemachatus haemachatus [TaxId:8626] [194346] (1 PDB entry)

    5. Species King cobra (Ophiophagus hannah) [TaxId:8665] [189806] (1 PDB entry)

    6. Species Mangrove snake (Boiga dendrophila) [TaxId:46286] [187789] (1 PDB entry)

    7. Species Naja oxiana [TaxId:8657] [254885] (2 PDB entries)

More info for Family g.7.1.1: Snake venom toxins

Timeline for Family g.7.1.1: Snake venom toxins:

• Family g.7.1.1: Snake venom toxins first appeared (with stable ids) in SCOP 1.55
  
• Family g.7.1.1: Snake venom toxins appears in SCOPe 2.04
  
• Family g.7.1.1: Snake venom toxins appears in SCOPe 2.06
  
• Family g.7.1.1: Snake venom toxins appears in the current release, SCOPe 2.08