SCOPe 2.01: Family g.3.7.1: Long-chain scorpion toxins

Lineage for Family g.3.7.1: Long-chain scorpion toxins

1. Root: SCOPe 2.01

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.7: Scorpion toxin-like [57095] (5 families)

5. Family g.3.7.1: Long-chain scorpion toxins [57096] (5 proteins)

Proteins:

1. alpha toxin [57111] (4 species)
   Anti-mammal and anti-insect scorpion toxin

   1. Species Chinese scorpion (Buthus martensii karsch) [TaxId:34649] [103539] (2 PDB entries)

   2. Species Leiurus quinquestriatus quinquestriatus, LQQIII [TaxId:6885] [57112] (1 PDB entry)

   3. Species Leiurus quinquestriatus [TaxId:6883] [186952] (1 PDB entry)

   4. Species Scorpion (Leiurus quinquestriatus hebraeus) [TaxId:6884] [57113] (2 PDB entries)

2. LQH III alpha-like toxin, LQH [57114] (1 species)

   • Species Hebraei scorpion (Leiurus quinquestriatus hebraeus) [TaxId:6884] [57115] (2 PDB entries)

3. Scorpion toxin [57097] (17 species)

   1. Species Bark scorpion (Centruroides sculpturatus), cse-v5 [TaxId:218467] [64536] (3 PDB entries)

   2. Species Brazilian scorpion (Tityus serrulatus) [TaxId:6887] [57110] (2 PDB entries)

   3. Species Centruroides sculpturatus, beta [TaxId:218467] [57099] (2 PDB entries)

   4. Species Centruroides sculpturatus, variant 1 [TaxId:218467] [57100] (2 PDB entries)

   5. Species Centruroides sculpturatus, variant 2 [TaxId:218467] [69933] (2 PDB entries)

   6. Species Centruroides sculpturatus, variant 3 [TaxId:218467] [57098] (1 PDB entry)

   7. Species Centruroides sculpturatus, variant V [TaxId:218467] [57101] (2 PDB entries)

   8. Species Chinese scorpion (Buthus martensii), toxin m1 [TaxId:34649] [57106] (11 PDB entries)
      Uniprot P45697

   9. Species Chinese scorpion (Buthus martensii), toxin m2 [TaxId:34649] [57107] (1 PDB entry)

   10. Species Chinese scorpion (Buthus martensii), toxin m4 [TaxId:34649] [57108] (1 PDB entry)

   11. Species Indian red scorpion (Buthus tamulus), neurotoxin [TaxId:34647] [57109] (2 PDB entries)

   12. Species Mexican scorpion (Centruroides noxius) [TaxId:6878] [111395] (1 PDB entry)
       Uniprot P63019

   13. Species Mexican scorpion (Centruroides noxius), toxin II [TaxId:6878] [57103] (3 PDB entries)

   14. Species Scorpion (Androctonus australis hector), Toxin II [TaxId:70175] [57102] (3 PDB entries)
       Uniprot P01484

   15. Species Scorpion (Buthotus judaicus), BJXTR-IT [TaxId:6863] [57104] (1 PDB entry)

   16. Species Scorpion (Buthus martensii), BmK IT-AP [TaxId:34649] [118240] (1 PDB entry)
       Uniprot O77091 19-90

   17. Species Scorpion (Buthus martensii), toxin m8 [TaxId:34649] [57105] (1 PDB entry)

4. Tx10 alpha-like toxin [103540] (1 species)

   • Species Chinese scorpion (Buthus martensii) [TaxId:34649] [103541] (1 PDB entry)

5. automated matches [190485] (2 species)
   not a true protein

   1. Species Leiurus quinquestriatus [TaxId:6883] [187424] (1 PDB entry)

   2. Species Leiurus quinquestriatus [TaxId:6884] [187842] (2 PDB entries)

More info for Family g.3.7.1: Long-chain scorpion toxins

Timeline for Family g.3.7.1: Long-chain scorpion toxins:

• Family g.3.7.1: Long-chain scorpion toxins first appeared (with stable ids) in SCOP 1.55
  
• Family g.3.7.1: Long-chain scorpion toxins appears in SCOP 1.75
  
• Family g.3.7.1: Long-chain scorpion toxins appears in SCOPe 2.02
  
• Family g.3.7.1: Long-chain scorpion toxins appears in the current release, SCOPe 2.08