Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. Class g: Small proteins [56992] (100 folds)
  3. Fold g.1: Insulin-like [56993] (1 superfamily)
    nearly all-alpha
    can be classified as disulfide-rich
  4. Superfamily g.1.1: Insulin-like [56994] (1 family) (S)
  5. Family g.1.1.1: Insulin-like [56995] (5 proteins)
  6. Protein Insulin [56996] (3 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [56998] (63 PDB entries)
    Uniprot P01308

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1a7f:
  2. Domain(s) for 1ai0:
    1. Domain d1ai0.1: 1ai0 B:,A: [43924]
      complexed with iph, zn
    2. Domain d1ai0.2: 1ai0 D:,C: [43925]
      complexed with iph, zn
    3. Domain d1ai0.3: 1ai0 F:,E: [43926]
      complexed with iph, zn
    4. Domain d1ai0.4: 1ai0 H:,G: [43927]
      complexed with iph, zn
    5. Domain d1ai0.5: 1ai0 J:,I: [43928]
      complexed with iph, zn
    6. Domain d1ai0.6: 1ai0 L:,K: [43929]
      complexed with iph, zn
  3. Domain(s) for 1aiy:
    1. Domain d1aiy.1: 1aiy B:,A: [43930]
      complexed with iph, zn
    2. Domain d1aiy.2: 1aiy D:,C: [43931]
      complexed with iph, zn
    3. Domain d1aiy.3: 1aiy F:,E: [43932]
      complexed with iph, zn
    4. Domain d1aiy.4: 1aiy H:,G: [43933]
      complexed with iph, zn
    5. Domain d1aiy.5: 1aiy J:,I: [43934]
      complexed with iph, zn
    6. Domain d1aiy.6: 1aiy L:,K: [43935]
      complexed with iph, zn
  4. Domain(s) for 1b9e:
    1. Domain d1b9e.1: 1b9e B:,A: [43885]
      mutant
    2. Domain d1b9e.2: 1b9e D:,C: [43886]
      mutant
  5. Domain(s) for 1ben:
    1. Domain d1ben.1: 1ben B:,A: [43837]
      complexed with cl, hbd, zn
    2. Domain d1ben.2: 1ben D:,C: [43838]
      complexed with cl, hbd, zn
  6. Domain(s) for 1bzv:
  7. Domain(s) for 1efe:
  8. Domain(s) for 1ev3:
    1. Domain d1ev3.1: 1ev3 B:,A: [43845]
      complexed with cl, crs, zn
    2. Domain d1ev3.2: 1ev3 D:,C: [43846]
      complexed with cl, crs, zn
  9. Domain(s) for 1ev6:
    1. Domain d1ev6.1: 1ev6 B:,A: [43857]
      complexed with cl, crs, na, zn
    2. Domain d1ev6.2: 1ev6 D:,C: [43858]
      complexed with cl, crs, na, zn
    3. Domain d1ev6.3: 1ev6 F:,E: [43859]
      complexed with cl, crs, na, zn
    4. Domain d1ev6.4: 1ev6 H:,G: [43860]
      complexed with cl, crs, na, zn
    5. Domain d1ev6.5: 1ev6 J:,I: [43861]
      complexed with cl, crs, na, zn
    6. Domain d1ev6.6: 1ev6 L:,K: [43862]
      complexed with cl, crs, na, zn
  10. Domain(s) for 1evr:
    1. Domain d1evr.1: 1evr B:,A: [43851]
      complexed with cl, na, rco, zn
    2. Domain d1evr.2: 1evr D:,C: [43852]
      complexed with cl, na, rco, zn
    3. Domain d1evr.3: 1evr F:,E: [43853]
      complexed with cl, na, rco, zn
    4. Domain d1evr.4: 1evr H:,G: [43854]
      complexed with cl, na, rco, zn
    5. Domain d1evr.5: 1evr J:,I: [43855]
      complexed with cl, na, rco, zn
    6. Domain d1evr.6: 1evr L:,K: [43856]
      complexed with cl, na, rco, zn
  11. Domain(s) for 1fu2:
    1. Domain d1fu2.1: 1fu2 B:,A: [43906]
      complexed with cl, na, zn
    2. Domain d1fu2.2: 1fu2 D:,C: [43907]
      complexed with cl, na, zn
    3. Domain d1fu2.3: 1fu2 F:,E: [43908]
      complexed with cl, na, zn
    4. Domain d1fu2.4: 1fu2 H:,G: [43909]
      complexed with cl, na, zn
  12. Domain(s) for 1fub:
    1. Domain d1fub.1: 1fub B:,A: [43892]
      complexed with cl, na, zn
    2. Domain d1fub.2: 1fub D:,C: [43893]
      complexed with cl, na, zn
  13. Domain(s) for 1g7a:
    1. Domain d1g7a.1: 1g7a B:,A: [60322]
      complexed with acn, cl, gol, zn
    2. Domain d1g7a.2: 1g7a D:,C: [60323]
      complexed with acn, cl, gol, zn
    3. Domain d1g7a.3: 1g7a F:,E: [60324]
      complexed with acn, cl, gol, zn
    4. Domain d1g7a.4: 1g7a H:,G: [60325]
      complexed with acn, cl, gol, zn
  14. Domain(s) for 1g7b:
    1. Domain d1g7b.1: 1g7b B:,A: [60326]
      complexed with acn, cl, gol, zn
    2. Domain d1g7b.2: 1g7b D:,C: [60327]
      complexed with acn, cl, gol, zn
    3. Domain d1g7b.3: 1g7b F:,E: [60328]
      complexed with acn, cl, gol, zn
    4. Domain d1g7b.4: 1g7b H:,G: [60329]
      complexed with acn, cl, gol, zn
  15. Domain(s) for 1guj:
    1. Domain d1guj.1: 1guj B:,A: [70582]
      structure at pH 2: the conditions promoting insulin fibre formation
      complexed with so4
    2. Domain d1guj.2: 1guj D:,C: [70583]
      structure at pH 2: the conditions promoting insulin fibre formation
      complexed with so4
  16. Domain(s) for 1hiq:
  17. Domain(s) for 1his:
  18. Domain(s) for 1hit:
  19. Domain(s) for 1hls:
  20. Domain(s) for 1htv:
    1. Domain d1htv.1: 1htv B:,A: [61255]
      complexed with zn
    2. Domain d1htv.2: 1htv D:,C: [61256]
      complexed with zn
    3. Domain d1htv.3: 1htv F:,E: [61257]
      complexed with zn
    4. Domain d1htv.4: 1htv H:,G: [61258]
      complexed with zn
    5. Domain d1htv.5: 1htv J:,I: [61259]
      complexed with zn
    6. Domain d1htv.6: 1htv L:,K: [61260]
      complexed with zn
  21. Domain(s) for 1hui:
  22. Domain(s) for 1iog:
  23. Domain(s) for 1ioh:
  24. Domain(s) for 1j73:
    1. Domain d1j73.1: 1j73 B:,A: [62670]
      an unstable insulin analog with native activity
      complexed with zn
    2. Domain d1j73.2: 1j73 D:,C: [62671]
      an unstable insulin analog with native activity
      complexed with zn
  25. Domain(s) for 1jca:
    1. Domain d1jca.1: 1jca B:,A: [62874]
      an unstable insulin analog with enhanced(?) activity
      complexed with zn
    2. Domain d1jca.2: 1jca D:,C: [62875]
      an unstable insulin analog with enhanced(?) activity
      complexed with zn
  26. Domain(s) for 1jco:
    • Domain d1jco.1: 1jco B:,A: [66503]
      a monomeric mutant (PT insulin)
      Alpha-galactosidase agl1
      mutant
  27. Domain(s) for 1k3m:
  28. Domain(s) for 1kmf:
  29. Domain(s) for 1lkq:
  30. Domain(s) for 1lph:
    1. Domain d1lph.1: 1lph B:,A: [43887]
      complexed with cl, iph, zn
    2. Domain d1lph.2: 1lph D:,C: [43888]
      complexed with cl, iph, zn
  31. Domain(s) for 1mhi:
  32. Domain(s) for 1mhj:
  33. Domain(s) for 1mso:
    1. Domain d1mso.1: 1mso B:,A: [85092]
      complexed with zn
    2. Domain d1mso.2: 1mso D:,C: [85093]
      complexed with zn
  34. Domain(s) for 1os3:
    1. Domain d1os3.1: 1os3 B:,A: [87372]
      complexed with cl, zn
    2. Domain d1os3.2: 1os3 D:,C: [87373]
      complexed with cl, zn
  35. Domain(s) for 1os4:
    1. Domain d1os4.1: 1os4 B:,A: [87374]
      complexed with zn
    2. Domain d1os4.2: 1os4 D:,C: [87375]
      complexed with zn
    3. Domain d1os4.3: 1os4 F:,E: [87376]
      complexed with zn
    4. Domain d1os4.4: 1os4 H:,G: [87377]
      complexed with zn
    5. Domain d1os4.5: 1os4 J:,I: [87378]
      complexed with zn
    6. Domain d1os4.6: 1os4 L:,K: [87379]
      complexed with zn
  36. Domain(s) for 1q4v:
    1. Domain d1q4v.1: 1q4v B:,A: [95830]
      complexed with iph, zn
    2. Domain d1q4v.2: 1q4v D:,C: [95831]
      complexed with iph, zn
  37. Domain(s) for 1qiy:
    1. Domain d1qiy.1: 1qiy B:,A: [43879]
      complexed with cl, iph, zn
    2. Domain d1qiy.2: 1qiy D:,C: [43880]
      complexed with cl, iph, zn
    3. Domain d1qiy.3: 1qiy F:,E: [43881]
      complexed with cl, iph, zn
    4. Domain d1qiy.4: 1qiy H:,G: [43882]
      complexed with cl, iph, zn
    5. Domain d1qiy.5: 1qiy J:,I: [43883]
      complexed with cl, iph, zn
    6. Domain d1qiy.6: 1qiy L:,K: [43884]
      complexed with cl, iph, zn
  38. Domain(s) for 1qiz:
    1. Domain d1qiz.1: 1qiz B:,A: [43873]
      complexed with cl, rco, zn
    2. Domain d1qiz.2: 1qiz D:,C: [43874]
      complexed with cl, rco, zn
    3. Domain d1qiz.3: 1qiz F:,E: [43875]
      complexed with cl, rco, zn
    4. Domain d1qiz.4: 1qiz H:,G: [43876]
      complexed with cl, rco, zn
    5. Domain d1qiz.5: 1qiz J:,I: [43877]
      complexed with cl, rco, zn
    6. Domain d1qiz.6: 1qiz L:,K: [43878]
      complexed with cl, rco, zn
  39. Domain(s) for 1qj0:
    1. Domain d1qj0.1: 1qj0 B:,A: [43889]
      complexed with cl, zn
    2. Domain d1qj0.2: 1qj0 D:,C: [43890]
      complexed with cl, zn
  40. Domain(s) for 1sf1:
  41. Domain(s) for 1sjt:
  42. Domain(s) for 1sju:
  43. Domain(s) for 1t1k:
  44. Domain(s) for 1t1p:
  45. Domain(s) for 1t1q:
  46. Domain(s) for 1trz:
    1. Domain d1trz.1: 1trz B:,A: [43843]
      complexed with cl, na, zn
    2. Domain d1trz.2: 1trz D:,C: [43844]
      complexed with cl, na, zn
  47. Domain(s) for 1tyl:
    1. Domain d1tyl.1: 1tyl B:,A: [43865]
      complexed with cl, tyl, zn
    2. Domain d1tyl.2: 1tyl D:,C: [43866]
      complexed with cl, tyl, zn
  48. Domain(s) for 1tym:
    1. Domain d1tym.1: 1tym B:,A: [43863]
      complexed with cl, tyl, zn
    2. Domain d1tym.2: 1tym D:,C: [43864]
      complexed with cl, tyl, zn
  49. Domain(s) for 1vkt:
  50. Domain(s) for 1xda:
    1. Domain d1xda.1: 1xda B:,A: [43847]
      complexed with cl, iph, myr, zn
    2. Domain d1xda.2: 1xda D:,C: [43848]
      complexed with cl, iph, myr, zn
    3. Domain d1xda.3: 1xda F:,E: [43849]
      complexed with cl, iph, myr, zn
    4. Domain d1xda.4: 1xda H:,G: [43850]
      complexed with cl, iph, myr, zn
  51. Domain(s) for 1xgl:
  52. Domain(s) for 1zeg:
    1. Domain d1zeg.1: 1zeg B:,A: [43841]
      complexed with cl, iph, zn
    2. Domain d1zeg.2: 1zeg D:,C: [43842]
      complexed with cl, iph, zn
  53. Domain(s) for 1zeh:
    1. Domain d1zeh.1: 1zeh B:,A: [43839]
      complexed with cl, crs, zn
    2. Domain d1zeh.2: 1zeh D:,C: [43840]
      complexed with cl, crs, zn
  54. Domain(s) for 1znj:
    1. Domain d1znj.1: 1znj B:,A: [43867]
      complexed with cl, iph, zn
    2. Domain d1znj.2: 1znj D:,C: [43868]
      complexed with cl, iph, zn
    3. Domain d1znj.3: 1znj F:,E: [43869]
      complexed with cl, iph, zn
    4. Domain d1znj.4: 1znj H:,G: [43870]
      complexed with cl, iph, zn
    5. Domain d1znj.5: 1znj J:,I: [43871]
      complexed with cl, iph, zn
    6. Domain d1znj.6: 1znj L:,K: [43872]
      complexed with cl, iph, zn
  55. Domain(s) for 2aiy:
    1. Domain d2aiy.1: 2aiy B:,A: [43918]
      complexed with iph
    2. Domain d2aiy.2: 2aiy D:,C: [43919]
      complexed with iph
    3. Domain d2aiy.3: 2aiy F:,E: [43920]
      complexed with iph
    4. Domain d2aiy.4: 2aiy H:,G: [43921]
      complexed with iph
    5. Domain d2aiy.5: 2aiy J:,I: [43922]
      complexed with iph
    6. Domain d2aiy.6: 2aiy L:,K: [43923]
      complexed with iph
  56. Domain(s) for 2hiu:
  57. Domain(s) for 2jmn:
  58. Domain(s) for 2lwz:
  59. Domain(s) for 3aiy:
    1. Domain d3aiy.1: 3aiy B:,A: [43911]
      complexed with iph
    2. Domain d3aiy.2: 3aiy D:,C: [43912]
      complexed with iph
    3. Domain d3aiy.3: 3aiy F:,E: [43913]
      complexed with iph
    4. Domain d3aiy.4: 3aiy H:,G: [43914]
      complexed with iph
    5. Domain d3aiy.5: 3aiy J:,I: [43915]
      complexed with iph
    6. Domain d3aiy.6: 3aiy L:,K: [43916]
      complexed with iph
  60. Domain(s) for 4aiy:
    1. Domain d4aiy.1: 4aiy B:,A: [43900]
      complexed with iph
    2. Domain d4aiy.2: 4aiy D:,C: [43901]
      complexed with iph
    3. Domain d4aiy.3: 4aiy F:,E: [43902]
      complexed with iph
    4. Domain d4aiy.4: 4aiy H:,G: [43903]
      complexed with iph
    5. Domain d4aiy.5: 4aiy J:,I: [43904]
      complexed with iph
    6. Domain d4aiy.6: 4aiy L:,K: [43905]
      complexed with iph
  61. Domain(s) for 5aiy:
    1. Domain d5aiy.1: 5aiy B:,A: [43894]
      complexed with iph
    2. Domain d5aiy.2: 5aiy D:,C: [43895]
      complexed with iph
    3. Domain d5aiy.3: 5aiy F:,E: [43896]
      complexed with iph
    4. Domain d5aiy.4: 5aiy H:,G: [43897]
      complexed with iph
    5. Domain d5aiy.5: 5aiy J:,I: [43898]
      complexed with iph
    6. Domain d5aiy.6: 5aiy L:,K: [43899]
      complexed with iph
  62. Domain(s) for 5wbt:
  63. Domain(s) for 6u46:

More info for Species Human (Homo sapiens) [TaxId:9606] from g.1.1.1 Insulin

Timeline for Species Human (Homo sapiens) [TaxId:9606] from g.1.1.1 Insulin: