Lineage for Protein: Apoptosis regulator Bcl-xL

  1. Root: SCOPe 2.06
  2. 2250849Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)
  3. 2250850Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 2250926Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 2250927Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 2250933Protein Apoptosis regulator Bcl-xL [56856] (3 species)

Species:

  1. 2250934Human (Homo sapiens) [TaxId:9606] [56857] (35 PDB entries)
    1. Domain for 1bxl:
    2. Domain for 1g5j:
    3. Domain for 1lxl:
    4. Domain for 1maz:
    5. Domain for 1r2d:
    6. Domain for 1r2e:
    7. Domain for 1r2g:
    8. Domain for 1r2h:
    9. Domain for 1r2i:
    10. Domain for 1ysg:
    11. Domain for 1ysi:
    12. Domain for 1ysn:
    13. Domain for 2b48:
    14. Domain for 2lpc:
    15. Domain for 2me8:
    16. Domain for 2me9:
    17. Domain for 2o1y:
    18. Domain for 2o2m:
    19. Domain for 2o2n:
    20. Domains for 2p1l:
      1. 2250957Domain d2p1la_: 2p1l A: [166945]
        automated match to d1g5ja_
      2. 2250958Domain d2p1lc_: 2p1l C: [166946]
        automated match to d1g5ja_
      3. 2250959Domain d2p1le_: 2p1l E: [166947]
        automated match to d1g5ja_
      4. 2250960Domain d2p1lg_: 2p1l G: [166948]
        automated match to d1g5ja_
    21. Domain for 2pon:
    22. Domains for 2yxj:
      1. 2250950Domain d2yxja_: 2yxj A: [170913]
        automated match to d1g5ja_
        complexed with cl, gol, n3c
      2. 2250951Domain d2yxjb_: 2yxj B: [170914]
        automated match to d1g5ja_
        complexed with cl, gol, n3c
    23. Domain for 3cva:
    24. Domains for 3io8:
      1. 2250955Domain d3io8a1: 3io8 A:1-197 [178474]
        Other proteins in same PDB: d3io8a2, d3io8c2
        automated match to d1g5ja_
        complexed with zn
      2. 2250956Domain d3io8c1: 3io8 C:1-197 [178475]
        Other proteins in same PDB: d3io8a2, d3io8c2
        automated match to d1g5ja_
        complexed with zn
    25. Domains for 3pl7:
      1. 2250966Domain d3pl7a_: 3pl7 A: [183827]
        automated match to d1g5ja_
      2. 2250967Domain d3pl7b_: 3pl7 B: [183828]
        automated match to d1g5ja_
    26. Domains for 3qkd:
      1. 2250946Domain d3qkda_: 3qkd A: [184464]
        automated match to d1g5ja_
        complexed with cl, gol, hi0
      2. 2250947Domain d3qkdb_: 3qkd B: [184465]
        automated match to d1g5ja_
        complexed with cl, gol, hi0
    27. Domain for 3sp7:
    28. Domain for 3spf:
    29. Domains for 3wiz:
      1. 2250964Domain d3wiza_: 3wiz A: [233972]
        automated match to d1g5ja_
        complexed with lc6, po4
      2. 2250965Domain d3wizb_: 3wiz B: [233973]
        automated match to d1g5ja_
        complexed with lc6, po4
    30. Domain for 4ehr:
    31. Domain for 4ppi:
    32. Domains for 4qvx:
      1. 2250962Domain d4qvxa_: 4qvx A: [275212]
        automated match to d2m03a_
        complexed with 3cq
      2. 2250963Domain d4qvxb_: 4qvx B: [275211]
        automated match to d2m03a_
        complexed with 3cq
    33. Domains for 4tuh:
      1. 2250938Domain d4tuha1: 4tuh A:1-196 [260442]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d1ysga_
        complexed with 38h, act, edo
      2. 2250939Domain d4tuhb1: 4tuh B:1-196 [263918]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      3. 2250940Domain d4tuhc1: 4tuh C:1-197 [263919]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      4. 2250941Domain d4tuhd_: 4tuh D: [263920]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      5. 2250942Domain d4tuhe_: 4tuh E: [263921]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      6. 2250943Domain d4tuhf1: 4tuh F:1-198 [263922]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      7. 2250944Domain d4tuhg1: 4tuh G:1-196 [263923]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      8. 2250945Domain d4tuhh1: 4tuh H:1-197 [263924]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
    34. Domain for 5l1y:
    35. Domain for 6bf2:
  2. 2250986Mouse (Mus musculus) [TaxId:10090] [103423] (9 PDB entries)
    1. Domain for 1pq0:
    2. Domain for 1pq1:
    3. Domain for 3ihc:
    4. Domain for 3ihd:
    5. Domains for 3ihf:
      1. 2250992Domain d3ihfa_: 3ihf A: [211686]
        automated match to d1r2da_
        mutant
      2. 2250993Domain d3ihfb_: 3ihf B: [211687]
        automated match to d1r2da_
        mutant
      3. 2250994Domain d3ihfc_: 3ihf C: [211688]
        automated match to d1r2da_
        mutant
      4. 2250995Domain d3ihfd_: 3ihf D: [211689]
        automated match to d1r2da_
        mutant
    6. Domain for 3iig:
    7. Domain for 3iih:
    8. Domains for 3ilb:
      1. 2250997Domain d3ilba_: 3ilb A: [211817]
        automated match to d1r2da_
        mutant
      2. 2250998Domain d3ilbn_: 3ilb N: [211818]
        automated match to d1r2da_
        mutant
    9. Domain for 3ilc:
  3. 2251000Norway rat (Rattus norvegicus) [TaxId:10116] [56858] (1 PDB entry)

More info for Protein Apoptosis regulator Bcl-xL from f.1.4.1: Bcl-2 inhibitors of programmed cell death

Timeline for Protein Apoptosis regulator Bcl-xL from f.1.4.1: Bcl-2 inhibitors of programmed cell death: