Class f: Membrane and cell surface proteins and peptides [56835] (58 folds) |
Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies) multi-helical domains of various folds which is thought to unfold in the membrane |
Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (1 family) PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain |
Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (10 proteins) Pfam PF00452 |
Protein Apoptosis regulator Bcl-xL [56856] (3 species) |
Human (Homo sapiens) [TaxId:9606] [56857] (15 PDB entries) |
Domain d1bxla_: 1bxl A: [43396] |
Domain d1g5ja_: 1g5j A: [43394] complex with peptide from Bad (CH B) mutant |
Domain d1lxla_: 1lxl A: [43395] |
Domain d1maza_: 1maz A: [43393] |
Domain d1r2da_: 1r2d A: [96864] |
Domain d1r2ea_: 1r2e A: [96865] mutant |
Domain d1r2ga_: 1r2g A: [96866] mutant |
Domain d1r2ha_: 1r2h A: [96867] mutant |
Domain d1r2ia_: 1r2i A: [96868] mutant |
Domain d1ysga1: 1ysg A:1-213 [123973] automatically matched to d1bxla_ complexed with 4fc, tn1 |
Domain d1ysia1: 1ysi A:1-213 [123974] automatically matched to d1bxla_ complexed with n3b |
Domain d1ysna1: 1ysn A:1-213 [123980] automatically matched to d1bxla_ complexed with 43b |
Domain d2b48a1: 2b48 A:1-196 [127816] automatically matched to d1maz__ |
Domain d2o1ya1: 2o1y A:1-213 [138881] automatically matched to d1bxla_ complexed with 43b |
Domain d2ponb1: 2pon B:57-212 [149723] automatically matched to d1g5ja_ |
Mouse (Mus musculus) [TaxId:10090] [103423] (3 PDB entries) |
Domain d1pq0a_: 1pq0 A: [94985] |
Domain d1pq1a_: 1pq1 A: [94986] complexed with bim peptide, chain B |
Domain d2bzwa1: 2bzw A:2-196 [129562] automatically matched to d1pq1a_ |
Rat (Rattus norvegicus) [TaxId:10116] [56858] (1 PDB entry) |
Domain d1af3a_: 1af3 A: [43397] |
Timeline for Protein Apoptosis regulator Bcl-xL from f.1.4.1: Bcl-2 inhibitors of programmed cell death: