Class c: Alpha and beta proteins (a/b) [51349] (130 folds) |
Fold c.108: HAD-like [56783] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456 |
Superfamily c.108.1: HAD-like [56784] (14 families) usually contains an insertion (sub)domain after strand 1 |
c.108.1.1: L-2-Haloacid dehalogenase, HAD [56785] (1 protein) the insertion subdomain is a 4-helical bundle |
c.108.1.2: Epoxide hydrolase, N-terminal domain [56789] (1 protein) the insertion subdomain is a 4-helical bundle |
c.108.1.3: Phosphonoacetaldehyde hydrolase [56792] (1 protein) the insertion subdomain is a 4-helical bundle |
c.108.1.4: Phosphoserine phosphatase [64511] (1 protein) the insertion subdomain is a 4-helical bundle |
c.108.1.5: Probable phosphatase YrbI [69467] (1 protein) the insertion subdomain is a beta-hairpin involved into tetramerisation |
c.108.1.6: beta-Phosphoglucomutase [75173] (1 protein) |
c.108.1.7: Calcium ATPase, catalytic domain P [81656] (1 protein) interrupted by a large insertion, domain N |
c.108.1.8: 5'(3')-deoxyribonucleotidase (dNT-2) [82382] (1 protein) the insertion subdomain is a 4-helical bundle; dephosphorylates dUMP and dTMP |
c.108.1.9: Polynucleotide kinase, phosphatase domain [82385] (1 protein) no insertion subdomains |
c.108.1.10: Predicted hydrolases Cof [82388] (4 proteins) contains an alpha+beta subdomain inserted into a new site after strand 3 |
c.108.1.11: Homoserine kinase ThrH [102304] (1 protein) the insertion subdomain is a rudiment 4-helical bundle |
c.108.1.12: Class B acid phosphatase [102307] (1 protein) the insertion subdomain is a helical hairpin |
c.108.1.13: Hypothetical protein MW1667 (SA1546) [102310] (1 protein) the insertion subdomain is multi-helical |
c.108.1.14: NagD-like [102317] (1 protein) contains an alpha/beta subdomain inserted after strand 3 (analogous to the Cof family) |
Timeline for Superfamily c.108.1: HAD-like: