SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Superfamily d.264.1: Prim-pol domain

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2215014Fold d.264: Prim-pol domain [56746] (1 superfamily)
    consists of two alpha+beta domains
  4. 2215015Superfamily d.264.1: Prim-pol domain [56747] (3 families) (S)


  1. 2215016d.264.1.1: PriA-like [56748] (2 protein domains)
    contains additional insert all-alpha subdomain
  2. 2215027d.264.1.2: Bifunctional DNA primase/polymerase N-terminal domain [103305] (1 protein)
  3. 2215033d.264.1.3: HP0184-like [143897] (1 protein)
    stand-alone domain with the least decorated Prim-pol fold

More info for Superfamily d.264.1: Prim-pol domain

Timeline for Superfamily d.264.1: Prim-pol domain: