SCOPe 2.03: Family e.11.1.1: Type II DNA topoisomerase

Lineage for Family e.11.1.1: Type II DNA topoisomerase

1. Root: SCOPe 2.03

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.11: Type II DNA topoisomerase [56718] (1 superfamily)
   4 domains: (1) toprim alpha/beta; (2) "winged helix"-like; (3) alpha+beta; (4) all-alpha

4. Superfamily e.11.1: Type II DNA topoisomerase [56719] (2 families)

5. Family e.11.1.1: Type II DNA topoisomerase [56720] (3 proteins)
   domain 2 contains the catalytic tyrosine residue

Proteins:

1. DNA Gyrase A [56723] (1 species)

   • Species Escherichia coli [TaxId:562] [56724] (4 PDB entries)

2. DNA topoisomerase II, C-terminal fragment (residues 410-1202) [56721] (1 species)
   the N-terminal fragment is homologous to known structure of DNA gyrase B

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56722] (3 PDB entries)

3. automated matches [191158] (5 species)
   not a true protein

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [189341] (2 PDB entries)

   2. Species Colwellia psychrerythraea [TaxId:167879] [189641] (1 PDB entry)

   3. Species Escherichia coli [TaxId:562] [226047] (1 PDB entry)

   4. Species Shigella flexneri [TaxId:623] [226392] (1 PDB entry)

   5. Species Vibrio fischeri [TaxId:312309] [226391] (1 PDB entry)

More info for Family e.11.1.1: Type II DNA topoisomerase

Timeline for Family e.11.1.1: Type II DNA topoisomerase:

• Family e.11.1.1: Type II DNA topoisomerase first appeared (with stable ids) in SCOP 1.55
  
• Family e.11.1.1: Type II DNA topoisomerase appears in SCOPe 2.02
  
• Family e.11.1.1: Type II DNA topoisomerase is called Family e.11.1.1: Type II DNA topoisomerase C-terminal domain-like in SCOPe 2.04
  
• Family e.11.1.1: Type II DNA topoisomerase appears in the current release, SCOPe 2.08, called Family e.11.1.1: Type II DNA topoisomerase C-terminal domain-like