Lineage for Fold e.10: Prokaryotic type I DNA topoisomerase
- Root: SCOP 1.73
Class e: Multi-domain proteins (alpha and beta) [56572] (53 folds) 
Fold e.10: Prokaryotic type I DNA topoisomerase [56711] (1 superfamily)
4 domains: (1) Toprim alpha/beta; (2&4) "winged helix"-like; (3) barrel: n=6, S=8
Superfamily:
e.10.1: Prokaryotic type I DNA topoisomerase [56712] (1 family) 
duplication: the protein chain passing through the domains 2-4 makes two structural repeats
The active site is formed by the toprim and "winged helix" domains (domains 1 and 4); these two domains are also found in the type II topoisomerase (DNA gyrase A) and in the alpha subunit of topoisomerase IV
More info for Fold e.10: Prokaryotic type I DNA topoisomerase
Timeline for Fold e.10: Prokaryotic type I DNA topoisomerase:
- Fold e.10: Prokaryotic type I DNA topoisomerase first appeared (with stable ids) in SCOP 1.55
- Fold e.10: Prokaryotic type I DNA topoisomerase appears in SCOP 1.71
- Fold e.10: Prokaryotic type I DNA topoisomerase appears in SCOP 1.75
- Fold e.10: Prokaryotic type I DNA topoisomerase appears in the current release, SCOPe 2.08