SCOP 1.75: Protein: Viral RNA polymerase

Lineage for Protein: Viral RNA polymerase

Root: SCOP 1.75
Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)
Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
"palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (2 proteins)
Protein Viral RNA polymerase [56695] (10 species)

Species:

Avian infectious bursal disease virus [TaxId:10995] [160955] (1 PDB entry)
Uniprot Q9Q6Q5 31-804
- Domain for 2pgg:
  - Domain d2pgga1: 2pgg A:31-804 [149462]
Bovine viral diarrhea virus [TaxId:11099] [103401] (3 PDB entries)
1. Domain for 1s48:
  - Domain d1s48a_: 1s48 A: [98475]
2. Domain for 1s49:
  - Domain d1s49a_: 1s49 A: [98476]
    complexed with gtp
3. Domains for 1s4f:
  1. Domain d1s4fa_: 1s4f A: [98495]
  2. Domain d1s4fb_: 1s4f B: [98496]
  3. Domain d1s4fc_: 1s4f C: [98497]
  4. Domain d1s4fd_: 1s4f D: [98498]
Foot-and-mouth disease virus [TaxId:12110] [111302] (8 PDB entries)
Uniprot Q9QCE4 1858-2327
1. Domain for 1u09:
  - Domain d1u09a_: 1u09 A: [107545]
2. Domain for 1wne:
  - Domain d1wnea_: 1wne A: [109434]
    complexed with mg
3. Domain for 2d7s:
  - Domain d2d7sa1: 2d7s A:1-474 [131326]
    automatically matched to d1u09a_
4. Domain for 2e9r:
  - Domain d2e9rx1: 2e9r X:1-476 [146732]
    automatically matched to d1u09a_
    complexed with mg, rtp
5. Domains for 2e9t:
  1. Domain d2e9ta1: 2e9t A:1-474 [146733]
    automatically matched to d1u09a_
    complexed with 5fu, mg, ppv
  2. Domain d2e9td1: 2e9t D:1-474 [146734]
    automatically matched to d1u09a_
    complexed with 5fu, mg, ppv
6. Domain for 2e9z:
  - Domain d2e9za1: 2e9z A:1-476 [146753]
    automatically matched to d1u09a_
    complexed with mg, ppv, utp
7. Domains for 2ec0:
  1. Domain d2ec0a1: 2ec0 A:1-470 [146776]
    automatically matched to d1u09a_
    complexed with mg, ppv
  2. Domain d2ec0d1: 2ec0 D:1-470 [146777]
    automatically matched to d1u09a_
    complexed with mg, ppv
8. Domain for 2f8e:
  - Domain d2f8ex1: 2f8e X:1-474 [133121]
    automatically matched to d1u09a_
    complexed with mg, mn, u5p
Hepatitis C virus [TaxId:11103] [56697] (21 PDB entries)
1. Domains for 1c2p:
  1. Domain d1c2pa_: 1c2p A: [43117]
  2. Domain d1c2pb_: 1c2p B: [43118]
2. Domains for 1csj:
  1. Domain d1csja_: 1csj A: [43120]
  2. Domain d1csjb_: 1csj B: [43121]
3. Domain for 1gx5:
  - Domain d1gx5a_: 1gx5 A: [70682]
    complexed with gtp, mn, mse
4. Domain for 1gx6:
  - Domain d1gx6a_: 1gx6 A: [70683]
    complexed with mn, mse, utp
5. Domains for 1nb4:
  1. Domain d1nb4a_: 1nb4 A: [85509]
  2. Domain d1nb4b_: 1nb4 B: [85510]
6. Domains for 1nb6:
  1. Domain d1nb6a_: 1nb6 A: [85511]
  2. Domain d1nb6b_: 1nb6 B: [85512]
    complexed with mn, utp
7. Domains for 1nb7:
  1. Domain d1nb7a_: 1nb7 A: [85513]
  2. Domain d1nb7b_: 1nb7 B: [85514]
    complexed with mn
8. Domains for 1nhu:
  1. Domain d1nhua_: 1nhu A: [85723]
  2. Domain d1nhub_: 1nhu B: [85724]
    complexed with 153
9. Domains for 1nhv:
  1. Domain d1nhva_: 1nhv A: [85725]
  2. Domain d1nhvb_: 1nhv B: [85726]
    complexed with 154
10. Domain for 1os5:
  - Domain d1os5a_: 1os5 A: [93475]
    complexed with nh1; mutant
11. Domain for 1quv:
  - Domain d1quva_: 1quv A: [43119]
12. Domain for 2brk:
  - Domain d2brka1: 2brk A:1-531 [129001]
    automatically matched to d1csja_
    complexed with cmf, mn
13. Domains for 2d3u:
  1. Domain d2d3ua1: 2d3u A:1-562 [131232]
    automatically matched to d1nhvb_
    complexed with cct
  2. Domain d2d3ub1: 2d3u B:1-562 [131233]
    automatically matched to d1nhvb_
    complexed with cct
14. Domains for 2d3z:
  1. Domain d2d3za1: 2d3z A:1-562 [131234]
    automatically matched to d1nhvb_
    complexed with fih
  2. Domain d2d3zb1: 2d3z B:1-562 [131235]
    automatically matched to d1nhvb_
    complexed with fih
15. Domains for 2d41:
  1. Domain d2d41a1: 2d41 A:1-562 [131236]
    automatically matched to d1nhvb_
    complexed with snh
  2. Domain d2d41b1: 2d41 B:1-562 [131237]
    automatically matched to d1nhvb_
    complexed with snh
16. Domains for 2gc8:
  1. Domain d2gc8a1: 2gc8 A:1-562 [134970]
    automatically matched to d1nhvb_
    complexed with 885
  2. Domain d2gc8b1: 2gc8 B:1-562 [134971]
    automatically matched to d1nhvb_
    complexed with 885
17. Domains for 2hwh:
  1. Domain d2hwha1: 2hwh A:1-564 [136822]
    automatically matched to d1c2pb_
    complexed with rna
  2. Domain d2hwhb1: 2hwh B:1-564 [136823]
    automatically matched to d1c2pb_
    complexed with rna
18. Domains for 2hwi:
  1. Domain d2hwia1: 2hwi A:1-564 [136824]
    automatically matched to d1c2pb_
    complexed with vrx
  2. Domain d2hwib1: 2hwi B:1-564 [136825]
    automatically matched to d1c2pb_
    complexed with vrx
19. Domains for 2i1r:
  1. Domain d2i1ra1: 2i1r A:1-564 [136986]
    automatically matched to d1c2pb_
    complexed with vxr
  2. Domain d2i1rb1: 2i1r B:1-564 [136987]
    automatically matched to d1c2pb_
    complexed with vxr
20. Domains for 2ijn:
  1. Domain d2ijna1: 2ijn A:1-564 [137478]
    automatically matched to d1c2pb_
    complexed with 221
  2. Domain d2ijnb1: 2ijn B:1-564 [137479]
    automatically matched to d1c2pb_
    complexed with 221
21. Domains for 2o5d:
  1. Domain d2o5da1: 2o5d A:1-564 [138918]
    automatically matched to d1c2pb_
    complexed with vr1
  2. Domain d2o5db1: 2o5d B:1-564 [138919]
    automatically matched to d1c2pb_
    complexed with vr1
Human rhinovirus 14, HRV-14 [TaxId:12131] [111301] (1 PDB entry)
Uniprot P03303 1720-2179
- Domain for 1xr5:
  - Domain d1xr5a_: 1xr5 A: [115864]
    complexed with sm
Human rhinovirus 16, HRV-16 [TaxId:31708] [111300] (1 PDB entry)
Uniprot Q82122 1694-2153
- Domains for 1xr7:
  1. Domain d1xr7a_: 1xr7 A: [115866]
  2. Domain d1xr7b_: 1xr7 B: [115867]
Human rhinovirus 1B, HRV-1B [TaxId:12129] [111299] (1 PDB entry)
Uniprot P12916 1698-2157
- Domain for 1xr6:
  - Domain d1xr6a_: 1xr6 A: [115865]
    complexed with k
Norwalk virus [TaxId:11983] [103400] (3 PDB entries)
1. Domains for 1sh0:
  1. Domain d1sh0a_: 1sh0 A: [98876]
  2. Domain d1sh0b_: 1sh0 B: [98877]
2. Domain for 1sh2:
  - Domain d1sh2a_: 1sh2 A: [98878]
3. Domains for 1sh3:
  1. Domain d1sh3a_: 1sh3 A: [98879]
  2. Domain d1sh3b_: 1sh3 B: [98880]
    complexed with mg
Poliovirus type 1, strain Mahoney [TaxId:12080] [56696] (12 PDB entries)
Uniprot P03300 1748-2208
1. Domain for 1ra6:
  - Domain d1ra6a_: 1ra6 A: [104879]
    complexed with acy, cas; mutant
2. Domain for 1ra7:
  - Domain d1ra7a_: 1ra7 A: [104880]
    complexed with acy, cas, gtp; mutant
3. Domain for 1raj:
  - Domain d1raja_: 1raj A: [104881]
    mutant
4. Domain for 1rdr:
  - Domain d1rdra_: 1rdr A: [43116]
    complexed with ca
5. Domain for 1tql:
  - Domain d1tqla_: 1tql A: [107235]
    complexed with acy, cas; mutant
6. Domains for 2ijd:
  1. Domain d2ijd12: 2ijd 1:184-644 [137475]
    Other proteins in same PDB: d2ijd11, d2ijd21
    automatically matched to d1ra6a_
    complexed with so4, zn; mutant
  2. Domain d2ijd22: 2ijd 2:184-644 [137477]
    Other proteins in same PDB: d2ijd11, d2ijd21
    automatically matched to d1ra6a_
    complexed with so4, zn; mutant
7. Domain for 2ily:
  - Domain d2ilya1: 2ily A:1-461 [137500]
    automatically matched to d1ra6a_
    complexed with acy, atp, cas, na; mutant
8. Domain for 2ilz:
  - Domain d2ilza1: 2ilz A:1-461 [137501]
    automatically matched to d1ra6a_
    complexed with acy, cas, gtp, mn, na; mutant
9. Domain for 2im0:
  - Domain d2im0a1: 2im0 A:1-461 [137502]
    automatically matched to d1ra6a_
    complexed with acy, cas, ctp, na; mutant
10. Domain for 2im1:
  - Domain d2im1a1: 2im1 A:1-461 [137503]
    automatically matched to d1ra6a_
    complexed with acy, cas, ctp, mn, na; mutant
11. Domain for 2im2:
  - Domain d2im2a1: 2im2 A:1-461 [137504]
    automatically matched to d1ra6a_
    complexed with acy, cas, na, utp; mutant
12. Domain for 2im3:
  - Domain d2im3a1: 2im3 A:1-461 [137505]
    automatically matched to d1ra6a_
    complexed with acy, cas, mn, na, utp; mutant
Rabbit hemorrhagic disease virus [TaxId:11976] [69882] (2 PDB entries)
1. Domains for 1khv:
  1. Domain d1khva_: 1khv A: [68627]
  2. Domain d1khvb_: 1khv B: [68628]
    complexed with lu
2. Domains for 1khw:
  1. Domain d1khwa_: 1khw A: [68629]
  2. Domain d1khwb_: 1khw B: [68630]
    complexed with mn

More info for Protein Viral RNA polymerase from e.8.1.4: RNA-dependent RNA-polymerase

Timeline for Protein Viral RNA polymerase from e.8.1.4: RNA-dependent RNA-polymerase:

Protein Viral RNA polymerase from e.8.1.4: RNA-dependent RNA-polymerase first appeared (with stable ids) in SCOP 1.55, called Protein RNA-dependent RNA-polymerase from e.8.1.4: RNA-dependent RNA-polymerase
Protein Viral RNA polymerase from e.8.1.4: RNA-dependent RNA-polymerase appears in SCOP 1.73
Protein Viral RNA polymerase from e.8.1.4: RNA-dependent RNA-polymerase appears in SCOPe 2.01
Protein Viral RNA polymerase from e.8.1.4: RNA-dependent RNA-polymerase appears in the current release, SCOPe 2.08