SCOP 1.71: Family e.8.1.4: RNA-dependent RNA-polymerase

Lineage for Family e.8.1.4: RNA-dependent RNA-polymerase

1. Root: SCOP 1.71

2. Class e: Multi-domain proteins (alpha and beta) [56572] (48 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (2 proteins)

Proteins:

1. Reovirus polymerase lambda3 [82841] (1 species)
   contains additional N-terminal domain (res. 1-380) and C-terminal "bracelet" domain (res. 891-1267)

   • Species Reovirus [TaxId:10891] [82842] (5 PDB entries)

2. Viral RNA polymerase [56695] (9 species)

   1. Species Bovine viral diarrhea virus [TaxId:11099] [103401] (3 PDB entries)

   2. Species Foot-and-mouth disease virus [111302] (2 PDB entries)

   3. Species Hepatitis C virus [TaxId:11103] [56697] (11 PDB entries)

   4. Species Human rhinovirus 14, HRV-14 [TaxId:12131] [111301] (1 PDB entry)

   5. Species Human rhinovirus 16, HRV-16 [TaxId:31708] [111300] (1 PDB entry)

   6. Species Human rhinovirus 1B, HRV-1B [TaxId:12129] [111299] (1 PDB entry)

   7. Species Norwalk virus [TaxId:11983] [103400] (3 PDB entries)

   8. Species Poliovirus type 1, strain Mahoney [TaxId:12080] [56696] (5 PDB entries)

   9. Species Rabbit hemorrhagic disease virus [TaxId:11976] [69882] (2 PDB entries)

More info for Family e.8.1.4: RNA-dependent RNA-polymerase

Timeline for Family e.8.1.4: RNA-dependent RNA-polymerase:

• Family e.8.1.4: RNA-dependent RNA-polymerase first appeared (with stable ids) in SCOP 1.55
  
• Family e.8.1.4: RNA-dependent RNA-polymerase appears in SCOP 1.69
  
• Family e.8.1.4: RNA-dependent RNA-polymerase appears in SCOP 1.73
  
• Family e.8.1.4: RNA-dependent RNA-polymerase appears in the current release, SCOPe 2.08