SCOP 1.63: Family e.8.1.4: RNA-dependent RNA-polymeras

Lineage for Family e.8.1.4: RNA-dependent RNA-polymeras

1. Root: SCOP 1.63

2. Class e: Multi-domain proteins (alpha and beta) [56572] (39 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymeras [56694] (2 proteins)

Proteins:

1. Reovirus polymerase lambda3 [82841] (1 species)
   contains additional N-terminal domain (res. 1-380) and C-terminal "bracelet" domain (res. 891-1267)

   • Species Reovirus [TaxId:10891] [82842] (5 PDB entries)

2. Viral RNA polymerase [56695] (3 species)

   1. Species Hepatitis C virus [TaxId:11103] [56697] (5 PDB entries)

   2. Species Poliovirus type 1, strain Mahoney [TaxId:12080] [56696] (1 PDB entry)

   3. Species Rabbit hemorrhagic disease virus [TaxId:11976] [69882] (2 PDB entries)

More info for Family e.8.1.4: RNA-dependent RNA-polymeras

Timeline for Family e.8.1.4: RNA-dependent RNA-polymeras:

• Family e.8.1.4: RNA-dependent RNA-polymeras first appeared (with stable ids) in SCOP 1.55, called Family e.8.1.4: RNA-dependent RNA-polymerase
  
• Family e.8.1.4: RNA-dependent RNA-polymeras was called Family e.8.1.4: Viral RNA-dependent RNA-polymerase in SCOP 1.61
  
• Family e.8.1.4: RNA-dependent RNA-polymeras appears in SCOP 1.65
  
• Family e.8.1.4: RNA-dependent RNA-polymeras appears in the current release, SCOPe 2.08, called Family e.8.1.4: RNA-dependent RNA-polymerase