Lineage for Protein: HIV-1 reverse transcriptase

  1. Root: SCOP 1.65
  2. 338536Class e: Multi-domain proteins (alpha and beta) [56572] (38 folds)
  3. 339256Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 339257Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 339321Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)
  6. 339322Protein HIV-1 reverse transcriptase [56689] (2 species)

Species:

  1. 339323Human immunodeficiency virus type 1 [TaxId:11676] [56690] (63 PDB entries)
    1. Domains for 1bqm:
      1. 339435Domain d1bqma2: 1bqm A:1-429 [43060]
        Other proteins in same PDB: d1bqma1
        complexed with hby; mutant
      2. 339436Domain d1bqmb_: 1bqm B: [43061]
        Other proteins in same PDB: d1bqma1
        complexed with hby; mutant
    2. Domains for 1bqn:
      1. 339443Domain d1bqna2: 1bqn A:1-429 [43064]
        Other proteins in same PDB: d1bqna1
        complexed with hby; mutant
      2. 339444Domain d1bqnb_: 1bqn B: [43065]
        Other proteins in same PDB: d1bqna1
        complexed with hby; mutant
    3. Domains for 1c0t:
      1. 339343Domain d1c0ta2: 1c0t A:4-429 [43082]
        Other proteins in same PDB: d1c0ta1
        complexed with bm1
      2. 339344Domain d1c0tb_: 1c0t B: [43083]
        Other proteins in same PDB: d1c0ta1
        complexed with bm1
    4. Domains for 1c0u:
      1. 339351Domain d1c0ua2: 1c0u A:1-429 [43084]
        Other proteins in same PDB: d1c0ua1
        complexed with bm5
      2. 339352Domain d1c0ub_: 1c0u B: [43085]
        Other proteins in same PDB: d1c0ua1
        complexed with bm5
    5. Domains for 1c1b:
      1. 339331Domain d1c1ba2: 1c1b A:1-429 [43076]
        Other proteins in same PDB: d1c1ba1
        complexed with gca
      2. 339332Domain d1c1bb_: 1c1b B: [43077]
        Other proteins in same PDB: d1c1ba1
        complexed with gca
    6. Domains for 1c1c:
      1. 339353Domain d1c1ca2: 1c1c A:1-429 [43086]
        Other proteins in same PDB: d1c1ca1
        complexed with 612
      2. 339354Domain d1c1cb_: 1c1c B: [43087]
        Other proteins in same PDB: d1c1ca1
        complexed with 612
    7. Domains for 1dlo:
      1. 339379Domain d1dloa2: 1dlo A:1-429 [43040]
        Other proteins in same PDB: d1dloa1
        mutant
      2. 339380Domain d1dlob_: 1dlo B: [43041]
        Other proteins in same PDB: d1dloa1
        mutant
    8. Domains for 1dtq:
      1. 339381Domain d1dtqa2: 1dtq A:4-429 [43096]
        Other proteins in same PDB: d1dtqa1
        complexed with fpt
      2. 339382Domain d1dtqb_: 1dtq B: [43097]
        Other proteins in same PDB: d1dtqa1
        complexed with fpt
    9. Domains for 1dtt:
      1. 339363Domain d1dtta2: 1dtt A:1-429 [43088]
        Other proteins in same PDB: d1dtta1
        complexed with ftc
      2. 339364Domain d1dttb_: 1dtt B: [43089]
        Other proteins in same PDB: d1dtta1
        complexed with ftc
    10. Domains for 1eet:
      1. 339345Domain d1eeta2: 1eet A:1-429 [43078]
        Other proteins in same PDB: d1eeta1
        complexed with bfu; mutant
      2. 339346Domain d1eetb_: 1eet B: [43079]
        Other proteins in same PDB: d1eeta1
        complexed with bfu; mutant
    11. Domains for 1ep4:
      1. 339365Domain d1ep4a2: 1ep4 A:4-429 [43092]
        Other proteins in same PDB: d1ep4a1
        complexed with s11
      2. 339366Domain d1ep4b_: 1ep4 B: [43093]
        Other proteins in same PDB: d1ep4a1
        complexed with s11
    12. Domains for 1fk9:
      1. 339347Domain d1fk9a2: 1fk9 A:4-429 [43080]
        Other proteins in same PDB: d1fk9a1
        complexed with efz
      2. 339348Domain d1fk9b_: 1fk9 B: [43081]
        Other proteins in same PDB: d1fk9a1
        complexed with efz
    13. Domains for 1fko:
      1. 339407Domain d1fkoa2: 1fko A:1-429 [43094]
        Other proteins in same PDB: d1fkoa1
        complexed with efz; mutant
      2. 339408Domain d1fkob_: 1fko B: [43095]
        Other proteins in same PDB: d1fkoa1
        complexed with efz; mutant
    14. Domains for 1fkp:
      1. 339421Domain d1fkpa2: 1fkp A:1-429 [43098]
        Other proteins in same PDB: d1fkpa1
        complexed with nvp; mutant
      2. 339422Domain d1fkpb_: 1fkp B: [43099]
        Other proteins in same PDB: d1fkpa1
        complexed with nvp; mutant
    15. Domain for 1har:
    16. Domains for 1hmv:
      1. 339401Domain d1hmva2: 1hmv A:1-429 [43046]
        Other proteins in same PDB: d1hmva1
        complexed with mg
      2. 339402Domain d1hmvb_: 1hmv B: [43047]
        Other proteins in same PDB: d1hmva1
        complexed with mg
    17. Domains for 1hni:
      1. 339397Domain d1hnia2: 1hni A:1-429 [43044]
        Other proteins in same PDB: d1hnia1
        complexed with aaa; mutant
      2. 339398Domain d1hnib_: 1hni B: [43045]
        Other proteins in same PDB: d1hnia1
        complexed with aaa; mutant
    18. Domains for 1hnv:
      1. 339425Domain d1hnva2: 1hnv A:1-429 [43056]
        Other proteins in same PDB: d1hnva1
        complexed with tbo; mutant
      2. 339426Domain d1hnvb_: 1hnv B: [43057]
        Other proteins in same PDB: d1hnva1
        complexed with tbo; mutant
    19. Domains for 1hpz:
      1. 339427Domain d1hpza2: 1hpz A:1-429 [61120]
        Other proteins in same PDB: d1hpza1
        complexed with aap; mutant
      2. 339428Domain d1hpzb_: 1hpz B: [61121]
        Other proteins in same PDB: d1hpza1
        complexed with aap; mutant
    20. Domains for 1hqe:
      1. 339399Domain d1hqea2: 1hqe A:1-429 [61131]
        Other proteins in same PDB: d1hqea1
        mutant
      2. 339400Domain d1hqeb_: 1hqe B: [61132]
        Other proteins in same PDB: d1hqea1
        mutant
    21. Domains for 1hqu:
      1. 339409Domain d1hqua2: 1hqu A:1-429 [61158]
        Other proteins in same PDB: d1hqua1
        complexed with hby; mutant
      2. 339410Domain d1hqub_: 1hqu B: [61159]
        Other proteins in same PDB: d1hqua1
        complexed with hby; mutant
    22. Domains for 1hvu:
      1. 339449Domain d1hvua2: 1hvu A:1-429 [43068]
        Other proteins in same PDB: d1hvua1, d1hvud1, d1hvug1, d1hvuj1
      2. 339450Domain d1hvub_: 1hvu B: [43069]
        Other proteins in same PDB: d1hvua1, d1hvud1, d1hvug1, d1hvuj1
      3. 339451Domain d1hvud2: 1hvu D:1-429 [43070]
        Other proteins in same PDB: d1hvua1, d1hvud1, d1hvug1, d1hvuj1
      4. 339452Domain d1hvue_: 1hvu E: [43071]
        Other proteins in same PDB: d1hvua1, d1hvud1, d1hvug1, d1hvuj1
      5. 339453Domain d1hvug2: 1hvu G:1-429 [43072]
        Other proteins in same PDB: d1hvua1, d1hvud1, d1hvug1, d1hvuj1
      6. 339454Domain d1hvuh_: 1hvu H: [43073]
        Other proteins in same PDB: d1hvua1, d1hvud1, d1hvug1, d1hvuj1
      7. 339455Domain d1hvuj2: 1hvu J:1-429 [43074]
        Other proteins in same PDB: d1hvua1, d1hvud1, d1hvug1, d1hvuj1
        protein/RNA complex
      8. 339456Domain d1hvuk_: 1hvu K: [43075]
        Other proteins in same PDB: d1hvua1, d1hvud1, d1hvug1, d1hvuj1
        protein/RNA complex
    23. Domains for 1hys:
      1. 339441Domain d1hysa2: 1hys A:1-429 [61418]
        Other proteins in same PDB: d1hysa1, d1hysc1, d1hysc2, d1hysd1, d1hysd2
        mutant
      2. 339442Domain d1hysb_: 1hys B: [61419]
        Other proteins in same PDB: d1hysa1, d1hysc1, d1hysc2, d1hysd1, d1hysd2
        mutant
    24. Domains for 1ikv:
      1. 339403Domain d1ikva2: 1ikv A:1-429 [62528]
        Other proteins in same PDB: d1ikva1
        complexed with efz; mutant
      2. 339404Domain d1ikvb_: 1ikv B: [62529]
        Other proteins in same PDB: d1ikva1
        complexed with efz; mutant
    25. Domains for 1ikw:
      1. 339383Domain d1ikwa2: 1ikw A:1-429 [62531]
        Other proteins in same PDB: d1ikwa1
        complexed with efz; mutant
      2. 339384Domain d1ikwb_: 1ikw B: [62532]
        Other proteins in same PDB: d1ikwa1
        complexed with efz; mutant
    26. Domains for 1ikx:
      1. 339355Domain d1ikxa2: 1ikx A:1-429 [62534]
        Other proteins in same PDB: d1ikxa1
        complexed with pnu; mutant
      2. 339356Domain d1ikxb_: 1ikx B: [62535]
        Other proteins in same PDB: d1ikxa1
        complexed with pnu; mutant
    27. Domains for 1iky:
      1. 339385Domain d1ikya2: 1iky A:1-429 [62537]
        Other proteins in same PDB: d1ikya1
        complexed with msd; mutant
      2. 339386Domain d1ikyb_: 1iky B: [62538]
        Other proteins in same PDB: d1ikya1
        complexed with msd; mutant
    28. Domains for 1j5o:
      1. 339447Domain d1j5oa2: 1j5o A:1-429 [71569]
        Other proteins in same PDB: d1j5oa1, d1j5oh1, d1j5oh2, d1j5ol1, d1j5ol2
        mutant
      2. 339448Domain d1j5ob_: 1j5o B: [71570]
        Other proteins in same PDB: d1j5oa1, d1j5oh1, d1j5oh2, d1j5ol1, d1j5ol2
        mutant
    29. Domains for 1jkh:
      1. 339341Domain d1jkha2: 1jkh A:2-429 [66798]
        Other proteins in same PDB: d1jkha1
        complexed with efz; mutant
      2. 339342Domain d1jkhb_: 1jkh B: [66799]
        Other proteins in same PDB: d1jkha1
        complexed with efz; mutant
    30. Domains for 1jla:
      1. 339333Domain d1jlaa2: 1jla A:1-429 [66834]
        Other proteins in same PDB: d1jlaa1
        complexed with tnk; mutant
      2. 339334Domain d1jlab_: 1jla B: [66835]
        Other proteins in same PDB: d1jlaa1
        complexed with tnk; mutant
    31. Domains for 1jlb:
      1. 339369Domain d1jlba2: 1jlb A:1-429 [66837]
        Other proteins in same PDB: d1jlba1
        complexed with nvp; mutant
      2. 339370Domain d1jlbb_: 1jlb B: [66838]
        Other proteins in same PDB: d1jlba1
        complexed with nvp; mutant
    32. Domains for 1jlc:
      1. 339405Domain d1jlca2: 1jlc A:1-429 [66840]
        Other proteins in same PDB: d1jlca1
        complexed with ftc; mutant
      2. 339406Domain d1jlcb_: 1jlc B: [66841]
        Other proteins in same PDB: d1jlca1
        complexed with ftc; mutant
    33. Domains for 1jle:
      1. 339411Domain d1jlea2: 1jle A:1-429 [66843]
        Other proteins in same PDB: d1jlea1
        mutant
      2. 339412Domain d1jleb_: 1jle B: [66844]
        Other proteins in same PDB: d1jlea1
        mutant
    34. Domains for 1jlf:
      1. 339371Domain d1jlfa2: 1jlf A:1-429 [66846]
        Other proteins in same PDB: d1jlfa1
        complexed with nvp; mutant
      2. 339372Domain d1jlfb_: 1jlf B: [66847]
        Other proteins in same PDB: d1jlfa1
        complexed with nvp; mutant
    35. Domains for 1jlg:
      1. 339359Domain d1jlga2: 1jlg A:2-429 [66849]
        Other proteins in same PDB: d1jlga1
        complexed with uc1; mutant
      2. 339360Domain d1jlgb_: 1jlg B: [66850]
        Other proteins in same PDB: d1jlga1
        complexed with uc1; mutant
    36. Domains for 1jlq:
      1. 339387Domain d1jlqa2: 1jlq A:1-429 [63174]
        Other proteins in same PDB: d1jlqa1
        complexed with sbn
      2. 339388Domain d1jlqb_: 1jlq B: [63175]
        Other proteins in same PDB: d1jlqa1
        complexed with sbn
    37. Domains for 1klm:
      1. 339361Domain d1klma2: 1klm A:2-429 [43038]
        Other proteins in same PDB: d1klma1
        complexed with spp
      2. 339362Domain d1klmb_: 1klm B: [43039]
        Other proteins in same PDB: d1klma1
        complexed with spp
    38. Domains for 1lw0:
      1. 339373Domain d1lw0a2: 1lw0 A:4-429 [78249]
        Other proteins in same PDB: d1lw0a1
        complexed with csd, nvp, po4; mutant
      2. 339374Domain d1lw0b_: 1lw0 B: [78250]
        Other proteins in same PDB: d1lw0a1
        complexed with csd, nvp, po4; mutant
    39. Domains for 1lw2:
      1. 339393Domain d1lw2a2: 1lw2 A:1-429 [78252]
        Other proteins in same PDB: d1lw2a1
        complexed with csd, po4, u05; mutant
      2. 339394Domain d1lw2b_: 1lw2 B: [78253]
        Other proteins in same PDB: d1lw2a1
        complexed with csd, po4, u05; mutant
    40. Domains for 1lwc:
      1. 339357Domain d1lwca2: 1lwc A:4-429 [78263]
        Other proteins in same PDB: d1lwca1
        complexed with csd, nvp, po4; mutant
      2. 339358Domain d1lwcb_: 1lwc B: [78264]
        Other proteins in same PDB: d1lwca1
        complexed with csd, nvp, po4; mutant
    41. Domains for 1lwe:
      1. 339367Domain d1lwea2: 1lwe A:1-429 [78268]
        Other proteins in same PDB: d1lwea1
        complexed with csd, nvp, po4; mutant
      2. 339368Domain d1lweb_: 1lwe B: [78269]
        Other proteins in same PDB: d1lwea1
        complexed with csd, nvp, po4; mutant
    42. Domains for 1lwf:
      1. 339375Domain d1lwfa2: 1lwf A:1-429 [78271]
        Other proteins in same PDB: d1lwfa1
        complexed with csd, nvp; mutant
      2. 339376Domain d1lwfb_: 1lwf B: [78272]
        Other proteins in same PDB: d1lwfa1
        complexed with csd, nvp; mutant
    43. Domains for 1n5y:
      1. 339433Domain d1n5ya2: 1n5y A:1-429 [80058]
        Other proteins in same PDB: d1n5ya1, d1n5yh1, d1n5yh2, d1n5yl1, d1n5yl2
        complexed with atm, mg, mrg; mutant
      2. 339434Domain d1n5yb_: 1n5y B: [80059]
        Other proteins in same PDB: d1n5ya1, d1n5yh1, d1n5yh2, d1n5yl1, d1n5yl2
        complexed with atm, mg, mrg; mutant
    44. Domains for 1n6q:
      1. 339431Domain d1n6qa2: 1n6q A:1-429 [80205]
        Other proteins in same PDB: d1n6qa1, d1n6qh1, d1n6qh2, d1n6ql1, d1n6ql2
        complexed with atm, mg, mrg; mutant
      2. 339432Domain d1n6qb_: 1n6q B: [80206]
        Other proteins in same PDB: d1n6qa1, d1n6qh1, d1n6qh2, d1n6ql1, d1n6ql2
        complexed with atm, mg, mrg; mutant
    45. Domains for 1qe1:
      1. 339423Domain d1qe1a2: 1qe1 A:1-429 [43054]
        Other proteins in same PDB: d1qe1a1
        mutant
      2. 339424Domain d1qe1b_: 1qe1 B: [43055]
        Other proteins in same PDB: d1qe1a1
        mutant
    46. Domains for 1rev:
      1. 339349Domain d1reva2: 1rev A:4-429 [43036]
        Other proteins in same PDB: d1reva1
        complexed with mg, trb
      2. 339350Domain d1revb_: 1rev B: [43037]
        Other proteins in same PDB: d1reva1
        complexed with mg, trb
    47. Domains for 1rt1:
      1. 339335Domain d1rt1a2: 1rt1 A:1-429 [43030]
        Other proteins in same PDB: d1rt1a1
      2. 339336Domain d1rt1b1: 1rt1 B:6-431 [43031]
        Other proteins in same PDB: d1rt1a1
        complexed with mkc
    48. Domains for 1rt2:
      1. 339337Domain d1rt2a2: 1rt2 A:1-429 [43032]
        Other proteins in same PDB: d1rt2a1
        complexed with tnk
      2. 339338Domain d1rt2b_: 1rt2 B: [43033]
        Other proteins in same PDB: d1rt2a1
        complexed with tnk
    49. Domains for 1rt3:
      1. 339413Domain d1rt3a2: 1rt3 A:2-429 [43052]
        Other proteins in same PDB: d1rt3a1
        complexed with u05; mutant
      2. 339414Domain d1rt3b_: 1rt3 B: [43053]
        Other proteins in same PDB: d1rt3a1
        complexed with u05; mutant
    50. Domains for 1rt4:
      1. 339389Domain d1rt4a2: 1rt4 A:1-429 [43100]
        Other proteins in same PDB: d1rt4a1
        complexed with po4, uc1
      2. 339390Domain d1rt4b_: 1rt4 B: [43101]
        Other proteins in same PDB: d1rt4a1
        complexed with po4, uc1
    51. Domains for 1rt5:
      1. 339391Domain d1rt5a2: 1rt5 A:1-429 [43102]
        Other proteins in same PDB: d1rt5a1
        complexed with po4, uc2
      2. 339392Domain d1rt5b_: 1rt5 B: [43103]
        Other proteins in same PDB: d1rt5a1
        complexed with po4, uc2
    52. Domains for 1rt6:
      1. 339377Domain d1rt6a2: 1rt6 A:1-429 [43090]
        Other proteins in same PDB: d1rt6a1
      2. 339378Domain d1rt6b1: 1rt6 B:6-431 [43091]
        Other proteins in same PDB: d1rt6a1
        complexed with po4, uc3
    53. Domains for 1rt7:
      1. 339415Domain d1rt7a2: 1rt7 A:4-429 [43104]
        Other proteins in same PDB: d1rt7a1
      2. 339416Domain d1rt7b1: 1rt7 B:6-431 [43105]
        Other proteins in same PDB: d1rt7a1
        complexed with po4, uc4
    54. Domains for 1rtd:
      1. 339417Domain d1rtda2: 1rtd A:1-429 [43048]
        Other proteins in same PDB: d1rtda1, d1rtdc1
      2. 339418Domain d1rtdb_: 1rtd B: [43049]
        Other proteins in same PDB: d1rtda1, d1rtdc1
      3. 339419Domain d1rtdc2: 1rtd C:1-429 [43050]
        Other proteins in same PDB: d1rtda1, d1rtdc1
        complexed with mg, ttp; mutant
      4. 339420Domain d1rtdd_: 1rtd D: [43051]
        Other proteins in same PDB: d1rtda1, d1rtdc1
        complexed with mg, ttp; mutant
    55. Domains for 1rth:
      1. 339327Domain d1rtha2: 1rth A:1-429 [43028]
        Other proteins in same PDB: d1rtha1
      2. 339328Domain d1rthb1: 1rth B:3-431 [43029]
        Other proteins in same PDB: d1rtha1
        complexed with cya, u05
    56. Domains for 1rti:
      1. 339395Domain d1rtia2: 1rti A:1-429 [43042]
        Other proteins in same PDB: d1rtia1
      2. 339396Domain d1rtib1: 1rti B:5-431 [43043]
        Other proteins in same PDB: d1rtia1
        complexed with cya, hef
    57. Domains for 1rtj:
      1. 339339Domain d1rtja2: 1rtj A:1-429 [43034]
        Other proteins in same PDB: d1rtja1
      2. 339340Domain d1rtjb1: 1rtj B:2-431 [43035]
        Other proteins in same PDB: d1rtja1
        complexed with cya
    58. Domains for 1tvr:
      1. 339437Domain d1tvra2: 1tvr A:1-429 [43058]
        Other proteins in same PDB: d1tvra1
        complexed with tb9; mutant
      2. 339438Domain d1tvrb_: 1tvr B: [43059]
        Other proteins in same PDB: d1tvra1
        complexed with tb9; mutant
    59. Domains for 1uwb:
      1. 339439Domain d1uwba2: 1uwb A:1-429 [43062]
        Other proteins in same PDB: d1uwba1
        complexed with tbo; mutant
      2. 339440Domain d1uwbb_: 1uwb B: [43063]
        Other proteins in same PDB: d1uwba1
        complexed with tbo; mutant
    60. Domains for 1vrt:
      1. 339324Domain d1vrta2: 1vrt A:4-429 [43023]
        Other proteins in same PDB: d1vrta1
        complexed with cya, mg, nev
      2. 339325Domain d1vrtb_: 1vrt B: [43024]
        Other proteins in same PDB: d1vrta1
        complexed with cya, mg, nev
    61. Domains for 1vru:
      1. 339329Domain d1vrua2: 1vru A:3-429 [43026]
        Other proteins in same PDB: d1vrua1
        complexed with aap, cya
      2. 339330Domain d1vrub_: 1vru B: [43027]
        Other proteins in same PDB: d1vrua1
        complexed with aap, cya
    62. Domains for 2hmi:
      1. 339429Domain d2hmia2: 2hmi A:1-429 [43106]
        Other proteins in same PDB: d2hmia1, d2hmic1, d2hmic2, d2hmid1, d2hmid2
        protein/protein/DNA complex; mutant
        less ordered regions are modeled as poly-ALA
      2. 339430Domain d2hmib_: 2hmi B: [43107]
        Other proteins in same PDB: d2hmia1, d2hmic1, d2hmic2, d2hmid1, d2hmid2
        protein/protein/DNA complex; mutant
    63. Domains for 3hvt:
      1. 339445Domain d3hvta2: 3hvt A:2-429 [43066]
        Other proteins in same PDB: d3hvta1
        complexed with nev
      2. 339446Domain d3hvtb_: 3hvt B: [43067]
        Other proteins in same PDB: d3hvta1
        complexed with nev
  2. 339457Human immunodeficiency virus type 2 [TaxId:11709] [82840] (1 PDB entry)

More info for Protein HIV-1 reverse transcriptase from e.8.1.2: Reverse transcriptase

Timeline for Protein HIV-1 reverse transcriptase from e.8.1.2: Reverse transcriptase: