Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds) |
Fold e.8: DNA/RNA polymerases [56671] (1 superfamily) divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members |
Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain |
Family e.8.1.1: DNA polymerase I [56673] (4 proteins) |
DNA polymerase I (Klenow fragment) [56674] (3 species) |
Species Bacillus stearothermophilus, newly identified strain as yet unnamed [TaxId:1422] [56677] (42 PDB entries) Uniprot Q5KWC1 299-878 # 99% sequence identity; Geobacillus kaustophilus TaxID:1462 Uniprot Q45458 298-876 # 88% sequence identity |
Species Escherichia coli [TaxId:562] [56675] (14 PDB entries) |
Species Thermus aquaticus [TaxId:271] [56676] (12 PDB entries) |
Family B DNA polymerase [56680] (7 species) |
Species Bacteriophage RB69 [TaxId:12353] [56681] (15 PDB entries) |
Species Desulfurococcus tok [TaxId:108142] [56684] (2 PDB entries) |
Species Escherichia coli [TaxId:562] [103399] (1 PDB entry) |
Species Pyrococcus kodakaraensis [TaxId:311400] [56685] (2 PDB entries) Uniprot P56689 1-758 # 93% sequence identity; Thermococcus kodakarensis KOD1 TaxID: 69014 |
Species Sulfolobus solfataricus [TaxId:2287] [118192] (1 PDB entry) Uniprot P26811 40-864 |
Species Thermococcus gorgonarius [TaxId:71997] [56682] (3 PDB entries) |
Species Thermococcus sp., 9on-7 [TaxId:35749] [56683] (1 PDB entry) |
phi29 DNA polymerase [118193] (1 species) |
Species Bacteriophage phi-29 [TaxId:10756] [118194] (8 PDB entries) Uniprot P03680 |
T7 phage DNA polymerase [56678] (1 species) |
Species Bacteriophage T7 [TaxId:10760] [56679] (16 PDB entries) Uniprot P00581 |
Timeline for Family e.8.1.1: DNA polymerase I: