Lineage for Protein: ADP ribosyl cyclase

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2114715Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
    3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
  4. 2117411Superfamily c.23.14: N-(deoxy)ribosyltransferase-like [52309] (4 families) (S)
    there are similar active site architectures as well as the catalytic mechanisms of functionally characterised members
  5. 2117455Family c.23.14.3: ADP ribosyl cyclase-like [56630] (3 proteins)
    contains extra N-terminal all-alpha subdomain
    automatically mapped to Pfam PF02267
  6. 2117456Protein ADP ribosyl cyclase [56631] (4 species)

Species:

  1. 2117457California sea hare (Aplysia californica) [TaxId:6500] [56632] (5 PDB entries)
    1. Domains for 1lbe:
      1. 2117464Domain d1lbea_: 1lbe A: [42773]
      2. 2117465Domain d1lbeb_: 1lbe B: [42774]
    2. Domains for 1r0s:
      1. 2117462Domain d1r0sa_: 1r0s A: [96737]
        mutant
      2. 2117463Domain d1r0sb_: 1r0s B: [96738]
        mutant
    3. Domains for 1r12:
      1. 2117458Domain d1r12a_: 1r12 A: [96780]
      2. 2117459Domain d1r12b_: 1r12 B: [96781]
    4. Domains for 1r15:
      1. 2117466Domain d1r15a_: 1r15 A: [96786]
        complexed with n, nca
      2. 2117467Domain d1r15b_: 1r15 B: [96787]
        complexed with n, nca
      3. 2117468Domain d1r15c_: 1r15 C: [96788]
        complexed with n, nca
      4. 2117469Domain d1r15d_: 1r15 D: [96789]
        complexed with n, nca
      5. 2117470Domain d1r15e_: 1r15 E: [96790]
        complexed with n, nca
      6. 2117471Domain d1r15f_: 1r15 F: [96791]
        complexed with n, nca
      7. 2117472Domain d1r15g_: 1r15 G: [96792]
        complexed with n, nca
      8. 2117473Domain d1r15h_: 1r15 H: [96793]
        complexed with n, nca
    5. Domains for 1r16:
      1. 2117460Domain d1r16a_: 1r16 A: [96794]
        complexed with n, pyf
      2. 2117461Domain d1r16b_: 1r16 B: [96795]
        complexed with n, pyf
  2. 2117474Cow (Bos taurus) [TaxId:9913] [189248] (3 PDB entries)
    1. Domains for 3gc6:
      1. 2117475Domain d3gc6a_: 3gc6 A: [176511]
        automated match to d2ef1b1
        complexed with so4
      2. 2117476Domain d3gc6b_: 3gc6 B: [176512]
        automated match to d2ef1b1
        complexed with so4
    2. Domains for 3ghh:
      1. 2117477Domain d3ghha_: 3ghh A: [176636]
        automated match to d2ef1b1
        complexed with 2nf, so4
      2. 2117478Domain d3ghhb_: 3ghh B: [176637]
        automated match to d2ef1b1
        complexed with 2nf, so4
    3. Domains for 3p5s:
      1. 2117479Domain d3p5sa_: 3p5s A: [248426]
        automated match to d3gc6a_
        complexed with avu, nag, so4
      2. 2117480Domain d3p5sb_: 3p5s B: [248427]
        automated match to d3gc6a_
        complexed with avu, nag, so4
  3. 2117481Human (Homo sapiens) [TaxId:9606] [159490] (42 PDB entries)
    Uniprot P28907 45-291
    1. Domains for 1yh3:
      1. 2117524Domain d1yh3a_: 1yh3 A: [162199]
        automated match to d2ef1a1
      2. 2117525Domain d1yh3b_: 1yh3 B: [162200]
        automated match to d2ef1a1
    2. Domains for 1zvm:
      1. 2117550Domain d1zvma_: 1zvm A: [162609]
        automated match to d2ef1a1
        complexed with so4
      2. 2117551Domain d1zvmb_: 1zvm B: [162610]
        automated match to d2ef1a1
        complexed with so4
      3. 2117552Domain d1zvmc_: 1zvm C: [162611]
        automated match to d2ef1a1
        complexed with so4
      4. 2117553Domain d1zvmd_: 1zvm D: [162612]
        automated match to d2ef1a1
        complexed with so4
    3. Domains for 2df1:
      1. 2117557Domain d2df1a_: 2df1 A: [303717]
        automated match to d2ef1a1
        complexed with epe
      2. 2117558Domain d2df1b_: 2df1 B: [303718]
        automated match to d2ef1a1
        complexed with epe
    4. Domain for 2ef1:
    5. Domains for 2hct:
      1. 2117528Domain d2hcta_: 2hct A: [165049]
        automated match to d2ef1a1
        complexed with nmn
      2. 2117529Domain d2hctb_: 2hct B: [165050]
        automated match to d2ef1a1
        complexed with nmn
    6. Domains for 2i65:
      1. 2117518Domain d2i65a_: 2i65 A: [165408]
        automated match to d2ef1a1
        complexed with nad
      2. 2117519Domain d2i65b_: 2i65 B: [165409]
        automated match to d2ef1a1
        complexed with nad
    7. Domains for 2i66:
      1. 2117495Domain d2i66a_: 2i66 A: [165410]
        automated match to d2ef1a1
        complexed with g1r, g2r
      2. 2117496Domain d2i66b_: 2i66 B: [165411]
        automated match to d2ef1a1
        complexed with g1r, g2r
    8. Domains for 2i67:
      1. 2117504Domain d2i67a_: 2i67 A: [165412]
        automated match to d2ef1a1
        complexed with apr
      2. 2117505Domain d2i67b_: 2i67 B: [165413]
        automated match to d2ef1a1
        complexed with apr
    9. Domains for 2o3q:
      1. 2117532Domain d2o3qa_: 2o3q A: [166524]
        automated match to d2ef1a1
        complexed with cxr
      2. 2117533Domain d2o3qb_: 2o3q B: [166525]
        automated match to d2ef1a1
        complexed with cxr
    10. Domains for 2o3r:
      1. 2117506Domain d2o3ra_: 2o3r A: [166526]
        automated match to d2ef1a1
        complexed with cxr
      2. 2117507Domain d2o3rb_: 2o3r B: [166527]
        automated match to d2ef1a1
        complexed with cxr
    11. Domains for 2o3s:
      1. 2117483Domain d2o3sa_: 2o3s A: [166528]
        automated match to d2ef1a1
        complexed with cxr
      2. 2117484Domain d2o3sb_: 2o3s B: [166529]
        automated match to d2ef1a1
        complexed with cxr
    12. Domains for 2o3t:
      1. 2117493Domain d2o3ta_: 2o3t A: [166530]
        automated match to d2ef1a1
        complexed with cgr
      2. 2117494Domain d2o3tb_: 2o3t B: [166531]
        automated match to d2ef1a1
        complexed with cgr
    13. Domains for 2o3u:
      1. 2117530Domain d2o3ua_: 2o3u A: [166532]
        automated match to d2ef1a1
        complexed with ngd
      2. 2117531Domain d2o3ub_: 2o3u B: [166533]
        automated match to d2ef1a1
        complexed with ngd
    14. Domains for 2pgj:
      1. 2117499Domain d2pgja_: 2pgj A: [167178]
        automated match to d2ef1a1
        complexed with n1c
      2. 2117500Domain d2pgjb_: 2pgj B: [167179]
        automated match to d2ef1a1
        complexed with n1c
    15. Domains for 2pgl:
      1. 2117508Domain d2pgla_: 2pgl A: [167180]
        automated match to d2ef1a1
        complexed with n1c
      2. 2117509Domain d2pglb_: 2pgl B: [167181]
        automated match to d2ef1a1
        complexed with n1c
    16. Domains for 3dzf:
      1. 2117534Domain d3dzfa_: 3dzf A: [174398]
        automated match to d2ef1a1
        complexed with rf5
      2. 2117535Domain d3dzfb_: 3dzf B: [174399]
        automated match to d2ef1a1
        complexed with rf5
      3. 2117536Domain d3dzfc_: 3dzf C: [174400]
        automated match to d2ef1a1
        complexed with rf5
      4. 2117537Domain d3dzfd_: 3dzf D: [174401]
        automated match to d2ef1a1
        complexed with rf5
      5. 2117538Domain d3dzfe_: 3dzf E: [174402]
        automated match to d2ef1a1
        complexed with rf5
      6. 2117539Domain d3dzff_: 3dzf F: [174403]
        automated match to d2ef1a1
        complexed with rf5
    17. Domains for 3dzg:
      1. 2117491Domain d3dzga_: 3dzg A: [174404]
        automated match to d2ef1a1
        complexed with nca, rf5
      2. 2117492Domain d3dzgb_: 3dzg B: [174405]
        automated match to d2ef1a1
        complexed with nca, rf5
    18. Domains for 3dzh:
      1. 2117485Domain d3dzha_: 3dzh A: [174406]
        automated match to d2ef1a1
        complexed with gtp
      2. 2117486Domain d3dzhb_: 3dzh B: [174407]
        automated match to d2ef1a1
        complexed with gtp
    19. Domains for 3dzi:
      1. 2117497Domain d3dzia_: 3dzi A: [174408]
        automated match to d2ef1a1
        complexed with n, rgt
      2. 2117498Domain d3dzib_: 3dzi B: [174409]
        automated match to d2ef1a1
        complexed with n, rgt
    20. Domains for 3dzj:
      1. 2117514Domain d3dzja_: 3dzj A: [174410]
        automated match to d2ef1a1
        complexed with nmn; mutant
      2. 2117515Domain d3dzjb_: 3dzj B: [174411]
        automated match to d2ef1a1
        complexed with nmn; mutant
    21. Domains for 3dzk:
      1. 2117502Domain d3dzka_: 3dzk A: [174412]
        automated match to d2ef1a1
        complexed with nmn
      2. 2117503Domain d3dzkb_: 3dzk B: [174413]
        automated match to d2ef1a1
        complexed with nmn
    22. Domain for 3f6y:
    23. Domains for 3i9m:
      1. 2117510Domain d3i9ma_: 3i9m A: [178182]
        automated match to d2ef1a1
        complexed with avu
      2. 2117511Domain d3i9mb_: 3i9m B: [178183]
        automated match to d2ef1a1
        complexed with avu
    24. Domains for 3i9n:
      1. 2117542Domain d3i9na_: 3i9n A: [178184]
        automated match to d2ef1a1
        complexed with avw
      2. 2117543Domain d3i9nb_: 3i9n B: [178185]
        automated match to d2ef1a1
        complexed with avw
    25. Domains for 3ofs:
      1. 2117544Domain d3ofsa_: 3ofs A: [182994]
        automated match to d2ef1a1
        complexed with avu
      2. 2117545Domain d3ofsb_: 3ofs B: [182995]
        automated match to d2ef1a1
        complexed with avu
      3. 2117546Domain d3ofsc_: 3ofs C: [182996]
        automated match to d2ef1a1
        complexed with avu
      4. 2117547Domain d3ofsd_: 3ofs D: [182997]
        automated match to d2ef1a1
        complexed with avu
      5. 2117548Domain d3ofse_: 3ofs E: [182998]
        automated match to d2ef1a1
        complexed with avu
      6. 2117549Domain d3ofsf_: 3ofs F: [182999]
        automated match to d2ef1a1
        complexed with avu
    26. Domain for 3raj:
    27. Domains for 3rok:
      1. 2117487Domain d3roka_: 3rok A: [185083]
        automated match to d2ef1a1
        complexed with 27c
      2. 2117488Domain d3rokb_: 3rok B: [185084]
        automated match to d2ef1a1
        complexed with 27c
    28. Domains for 3rom:
      1. 2117520Domain d3roma_: 3rom A: [185085]
        Other proteins in same PDB: d3romb2
        automated match to d2ef1a1
        complexed with 48z
      2. 2117521Domain d3romb1: 3rom B:45-296 [185086]
        Other proteins in same PDB: d3romb2
        automated match to d2ef1a1
        complexed with 48z
    29. Domains for 3rop:
      1. 2117512Domain d3ropa_: 3rop A: [185087]
        automated match to d2ef1a1
        complexed with 50a, nca
      2. 2117513Domain d3ropb_: 3rop B: [185088]
        automated match to d2ef1a1
        complexed with 50a, nca
    30. Domains for 3roq:
      1. 2117540Domain d3roqa_: 3roq A: [185089]
        automated match to d2ef1a1
        complexed with 46z
      2. 2117541Domain d3roqb_: 3roq B: [185090]
        automated match to d2ef1a1
        complexed with 46z
    31. Domains for 3u4h:
      1. 2117516Domain d3u4ha_: 3u4h A: [200931]
        automated match to d2i66a_
        complexed with c8r
      2. 2117517Domain d3u4hb_: 3u4h B: [193464]
        automated match to d3dzha_
        complexed with c8r
    32. Domains for 3u4i:
      1. 2117526Domain d3u4ia_: 3u4i A: [217191]
        automated match to d2i66a_
        complexed with cvr
      2. 2117527Domain d3u4ib_: 3u4i B: [217192]
        automated match to d2i66a_
        complexed with cvr
    33. Domain for 4cmh:
    34. Domains for 4f45:
      1. 2117522Domain d4f45a1: 4f45 A:46-296 [196738]
        Other proteins in same PDB: d4f45a2, d4f45b2
        automated match to d2o3ta_
        complexed with dn4; mutant
      2. 2117523Domain d4f45b1: 4f45 B:46-296 [201992]
        Other proteins in same PDB: d4f45a2, d4f45b2
        automated match to d4f45a_
        complexed with dn4; mutant
    35. Domains for 4f46:
      1. 2117489Domain d4f46a1: 4f46 A:46-291 [196739]
        Other proteins in same PDB: d4f46a2, d4f46b2
        automated match to d3roka_
        complexed with dn4, dvn
      2. 2117490Domain d4f46b1: 4f46 B:46-296 [196737]
        Other proteins in same PDB: d4f46a2, d4f46b2
        automated match to d3roka_
        complexed with dn4, dvn
    36. Domain for 4ogw:
    37. Domains for 4tmf:
      1. 2117559Domain d4tmfa1: 4tmf A:50-296 [272708]
        Other proteins in same PDB: d4tmfa2, d4tmfb2
        automated match to d4f45a_
        complexed with js2
      2. 2117560Domain d4tmfb1: 4tmf B:50-291 [272709]
        Other proteins in same PDB: d4tmfa2, d4tmfb2
        automated match to d4f45a_
        complexed with js2
    38. Domain for 4xjs:
    39. Domain for 4xjt:
    40. Domains for 5f1k:
      1. 2117562Domain d5f1ka_: 5f1k A: [318382]
        Other proteins in same PDB: d5f1kc_, d5f1kd_
        automated match to d1zvmc_
      2. 2117563Domain d5f1kb_: 5f1k B: [318647]
        Other proteins in same PDB: d5f1kc_, d5f1kd_
        automated match to d1zvmc_
    41. Domain for 5f1o:
    42. Domain for 5f21:
  4. 2117567Mouse (Mus musculus) [TaxId:10090] [188367] (1 PDB entry)

More info for Protein ADP ribosyl cyclase from c.23.14.3: ADP ribosyl cyclase-like

Timeline for Protein ADP ribosyl cyclase from c.23.14.3: ADP ribosyl cyclase-like: