![]() | Class e: Multi-domain proteins (alpha and beta) [56572] (53 folds) |
![]() | Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily) contains a cluster of helices and an alpha+beta sandwich |
![]() | Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (3 families) ![]() |
![]() | Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (16 proteins) |
![]() | Protein beta-Lactamase, class A [56606] (15 species) |
![]() | Bacillus licheniformis [TaxId:1402] [56612] (5 PDB entries) |
![]() | Domain d1i2sa_: 1i2s A: [71104] |
![]() | Domain d1i2sb_: 1i2s B: [71105] complexed with cit, na |
![]() | Domain d1i2wa_: 1i2w A: [71106] |
![]() | Domain d1i2wb_: 1i2w B: [71107] complexed with cfx, out |
![]() | Domain d1mbla_: 1mbl A: [42723] |
![]() | Domain d1mblb_: 1mbl B: [42724] complexed with so4; mutant |
![]() | Domain d2blma_: 2blm A: [42725] |
![]() | Domain d2blmb_: 2blm B: [42726] CA-atoms only |
![]() | Domain d4blma_: 4blm A: [42721] |
![]() | Domain d4blmb_: 4blm B: [42722] |
![]() | Enterobacter cloacae, NMC-A carbapenemase [TaxId:550] [56613] (2 PDB entries) |
![]() | Domain d1buea_: 1bue A: [42727] |
![]() | Domain d1bula_: 1bul A: [42728] complexed with ap3, mes |
![]() | Escherichia coli, TEM-1 [TaxId:562] [56607] (29 PDB entries) |
![]() | Domain d1axba_: 1axb A: [42695] complexed with fos; mutant |
![]() | Domain d1bt5a_: 1bt5 A: [42693] complexed with im2, so4; mutant |
![]() | Domain d1btla_: 1btl A: [42691] complexed with so4 |
![]() | Domain d1ck3a_: 1ck3 A: [42698] mutant |
![]() | Domain d1erma_: 1erm A: [42690] complexed with bji |
![]() | Domain d1eroa_: 1ero A: [42700] complexed with bjp |
![]() | Domain d1erqa_: 1erq A: [42697] complexed with bjh |
![]() | Domain d1esua_: 1esu A: [42696] complexed with so4; mutant |
![]() | Domain d1fqga_: 1fqg A: [42699] acyl-enzyme intermediate complexed with pnm; mutant |
![]() | Domain d1jtda_: 1jtd A: [67264] Other proteins in same PDB: d1jtdb_ complexed with ca |
![]() | Domain d1jtga_: 1jtg A: [67266] Other proteins in same PDB: d1jtgb_, d1jtgd_ |
![]() | Domain d1jtgc_: 1jtg C: [67268] Other proteins in same PDB: d1jtgb_, d1jtgd_ complexed with ca; mutant |
![]() | Domain d1jvja_: 1jvj A: [71896] complexed with im2, k; mutant |
![]() | Domain d1jwpa_: 1jwp A: [71917] complexed with po4; mutant |
![]() | Domain d1jwva_: 1jwv A: [71918] complexed with cb4, k; mutant |
![]() | Domain d1jwza_: 1jwz A: [71922] TEM-64 variant complexed with 105; mutant |
![]() | Domain d1lhya_: 1lhy A: [77967] TEM-30 variant complexed with po4; mutant |
![]() | Domain d1li0a_: 1li0 A: [77968] TEM-32 variant complexed with bct, k; mutant |
![]() | Domain d1li9a_: 1li9 A: [77969] TEM-34 variant complexed with k, po4; mutant |
![]() | Domain d1m40a_: 1m40 A: [74437] ultra high resolution structure complexed with cb4, k, po4; mutant |
![]() | Domain d1nxya_: 1nxy A: [92313] complexed with k, sm2; mutant |
![]() | Domain d1ny0a_: 1ny0 A: [92314] complexed with k, nbf, po4; mutant |
![]() | Domain d1nyma_: 1nym A: [92344] complexed with cxb, k, po4; mutant |
![]() | Domain d1nyya_: 1nyy A: [92362] complexed with 105; mutant |
![]() | Domain d1pzoa_: 1pzo A: [95464] complexed with cbt; mutant |
![]() | Domain d1pzpa_: 1pzp A: [95465] complexed with fta; mutant |
![]() | Domain d1s0wa_: 1s0w A: [98309] Other proteins in same PDB: d1s0wc_, d1s0wd_ |
![]() | Domain d1s0wb_: 1s0w B: [98310] Other proteins in same PDB: d1s0wc_, d1s0wd_ complexed with ca; mutant |
![]() | Domain d1tema_: 1tem A: [42692] complexed with alp |
![]() | Domain d1xpba_: 1xpb A: [42694] complexed with so4 |
![]() | Domain d1zg4a1: 1zg4 A:26-290 [125009] automatically matched to d1axb__ |
![]() | Escherichia coli, TOHO-1 [TaxId:562] [56608] (5 PDB entries) |
![]() | Domain d1bzaa_: 1bza A: [42701] complexed with so4; mutant |
![]() | Domain d1iyoa_: 1iyo A: [76970] complexed with cef, so4; mutant |
![]() | Domain d1iypa_: 1iyp A: [76971] complexed with cep, so4; mutant |
![]() | Domain d1iyqa_: 1iyq A: [76972] complexed with pnm, so4; mutant |
![]() | Domain d1iysa_: 1iys A: [90723] complexed with so4 |
![]() | Klebsiella pneumoniae, SHV-1 [TaxId:573] [56609] (11 PDB entries) inhibited by tazobactam |
![]() | Domain d1onga_: 1ong A: [93356] complexed with ma4, wy4 |
![]() | Domain d1q2pa_: 1q2p A: [104501] complexed with ma4, wy2 |
![]() | Domain d1rcja_: 1rcj A: [97293] complexed with ma4, tbi; mutant |
![]() | Domain d1shva_: 1shv A: [42703] complexed with ma4 |
![]() | Domain d1tdga_: 1tdg A: [112397] complexed with ma4, mdd, mpd, tbe; mutant |
![]() | Domain d1tdla_: 1tdl A: [112398] complexed with epe, ma4; mutant |
![]() | Domain d1vm1a_: 1vm1 A: [108875] complexed with akr, ma4, taz, tbe |
![]() | Domain d2a3ua1: 2a3u A:26-292 [126098] automatically matched to d1rcja_ complexed with epe, ma4, tsl; mutant |
![]() | Domain d2a49a1: 2a49 A:26-292 [126149] automatically matched to d1rcja_ complexed with epe, ma4, tem; mutant |
![]() | Domain d2g2ua1: 2g2u A:26-292 [134540] Other proteins in same PDB: d2g2ub1 automatically matched to d1onga_ |
![]() | Domain d2h5sa1: 2h5s A:26-292 [136168] automatically matched to d1onga_ complexed with ma4, sa2 |
![]() | Klebsiella pneumoniae, SHV-2 [TaxId:573] [90082] (1 PDB entry) almost identical sequence to SHV-1 |
![]() | Domain d1n9ba_: 1n9b A: [85463] complexed with epe, ma4, mpd |
![]() | Klebsiella pneumoniae, TEM52 [TaxId:573] [64473] (1 PDB entry) |
![]() | Domain d1htza_: 1htz A: [61262] |
![]() | Domain d1htzb_: 1htz B: [61263] |
![]() | Domain d1htzc_: 1htz C: [61264] |
![]() | Domain d1htzd_: 1htz D: [61265] |
![]() | Domain d1htze_: 1htz E: [61266] |
![]() | Domain d1htzf_: 1htz F: [61267] mutant |
![]() | Mycobacterium fortuitum [TaxId:1766] [56615] (1 PDB entry) |
![]() | Domain d2cc1a1: 2cc1 A:27-293 [130211] automatically matched to d1mfoa_ |
![]() | Proteus vulgaris [TaxId:585] [75596] (1 PDB entry) |
![]() | Domain d1hzoa_: 1hzo A: [71092] |
![]() | Domain d1hzob_: 1hzo B: [71093] complexed with mes |
![]() | Pseudomonas aeruginosa, PER-1 [TaxId:287] [56616] (1 PDB entry) |
![]() | Domain d1e25a_: 1e25 A: [42731] complexed with so4; mutant |
![]() | Pseudomonas aeruginosa, PSE-4 carbenicillinase [TaxId:287] [56610] (2 PDB entries) |
![]() | Domain d1g68a_: 1g68 A: [42705] complexed with so4 |
![]() | Domain d1g6aa_: 1g6a A: [42704] complexed with so4; mutant |
![]() | Serratia marcescens, Sme-1 [TaxId:615] [56617] (1 PDB entry) imipenem-hydrolyzing |
![]() | Domain d1dy6a_: 1dy6 A: [42732] |
![]() | Domain d1dy6b_: 1dy6 B: [42733] |
![]() | Staphylococcus aureus [TaxId:1280] [56611] (16 PDB entries) |
![]() | Domain d1alqa_: 1alq A: [42707] circularly permuted complexed with co3, so4; mutant |
![]() | Domain d1blca_: 1blc A: [42714] complexed with cem, so4, tem |
![]() | Domain d1blha_: 1blh A: [42713] complexed with fos |
![]() | Domain d1blpa_: 1blp A: [42716] mutant |
![]() | Domain d1djaa_: 1dja A: [42706] mutant |
![]() | Domain d1djba_: 1djb A: [42711] mutant |
![]() | Domain d1djca_: 1djc A: [42710] complexed with so4; mutant |
![]() | Domain d1ghia_: 1ghi A: [60518] complexed with co3; mutant |
![]() | Domain d1ghma_: 1ghm A: [60519] complexed with ced, co3, so4; mutant |
![]() | Domain d1ghpa_: 1ghp A: [60520] complexed with pnm, so4; mutant |
![]() | Domain d1kgea_: 1kge A: [42708] mutant |
![]() | Domain d1kgfa_: 1kgf A: [42712] mutant |
![]() | Domain d1kgga_: 1kgg A: [42715] complexed with so4; mutant |
![]() | Domain d1omea_: 1ome A: [42717] |
![]() | Domain d1omeb_: 1ome B: [42718] omega loop deletion mutant (residues 163-178 deleted) |
![]() | Domain d1pioa_: 1pio A: [42719] |
![]() | Domain d1piob_: 1pio B: [42720] mutant |
![]() | Domain d3blma_: 3blm A: [42709] |
![]() | Stenotrophomonas maltophilia, L2 [TaxId:40324] [103374] (2 PDB entries) |
![]() | Domain d1n4oa_: 1n4o A: [91621] |
![]() | Domain d1n4ob_: 1n4o B: [91622] complexed with so4 |
![]() | Domain d1o7ea_: 1o7e A: [92622] |
![]() | Domain d1o7eb_: 1o7e B: [92623] complexed with gol, so4 |
![]() | Streptomyces albus G [TaxId:1962] [56614] (1 PDB entry) |
![]() | Domain d1bsga_: 1bsg A: [42729] complexed with act |
Timeline for Protein beta-Lactamase, class A from e.3.1.1: beta-Lactamase/D-ala carboxypeptidase: