SCOP 1.75: Family e.1.1.1: Serpins

Lineage for Family e.1.1.1: Serpins

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (1 family)

5. Family e.1.1.1: Serpins [56575] (16 proteins)

Proteins:

1. Alaserpin (serpin 1) [64469] (1 species)

   • Species Tobacco hornworm (Manduca sexta) [TaxId:7130] [64470] (1 PDB entry)
     Michaelis serpin-trypsin complex

2. Antichymotrypsin, alpha-1 [56580] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [56581] (5 PDB entries)

3. Antithrombin [56584] (2 species)

   1. Species Cow (Bos taurus) [TaxId:9913] [56585] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [56586] (25 PDB entries)
      Uniprot P01008

4. Antitrypsin, alpha-1 [56582] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [56583] (15 PDB entries)

5. Elastase inhibitor [56576] (1 species)

   • Species Horse (Equus caballus) [TaxId:9796] [56577] (1 PDB entry)

6. Heparin cofactor II (Hc-II, leuserpin 2) [82833] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [82834] (2 PDB entries)

7. Maspin [118179] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [118180] (2 PDB entries)
     Uniprot P36952

8. Neuroserpin [69871] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [69872] (1 PDB entry)

9. Ovalbumin [56578] (1 species)

   • Species Hen (Gallus gallus) [TaxId:9031] [56579] (3 PDB entries)

10. Pigment epithelium-derived factor, PEDF [64471] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [64472] (1 PDB entry)

11. Plasminogen activator inhibitor-1 [56587] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [56588] (9 PDB entries)

12. Plasminogen activator inhibitor-2 [56589] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [56590] (2 PDB entries)

13. Protein C inhibitor [82835] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [82836] (1 PDB entry)

14. Serpin K [56591] (1 species)

    • Species Tobacco hawkmoth (Manduca sexta) [TaxId:7130] [56592] (1 PDB entry)

15. Thermopin [90080] (1 species)
    Serpin from a thermophilic prokaryote

    • Species Thermobifida fusca [TaxId:2021] [90081] (2 PDB entries)
      Uniprot Q47NK3

16. Viral serpin crmA (cytokine response modifier protein) [56593] (1 species)

    • Species Cowpox virus [TaxId:10243] [56594] (3 PDB entries)

More info for Family e.1.1.1: Serpins

Timeline for Family e.1.1.1: Serpins:

• Family e.1.1.1: Serpins first appeared (with stable ids) in SCOP 1.55
  
• Family e.1.1.1: Serpins appears in SCOP 1.73
  
• Family e.1.1.1: Serpins appears in SCOPe 2.01
  
• Family e.1.1.1: Serpins appears in the current release, SCOPe 2.08