SCOPe 2.08: Protein: Substrate-binding domain of HMG-CoA reductase

Lineage for Protein: Substrate-binding domain of HMG-CoA reductase

Root: SCOPe 2.08
Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
Fold d.179: Substrate-binding domain of HMG-CoA reductase [56541] (1 superfamily)
unusual fold
Superfamily d.179.1: Substrate-binding domain of HMG-CoA reductase [56542] (1 family)
Family d.179.1.1: Substrate-binding domain of HMG-CoA reductase [56543] (1 protein)
Protein Substrate-binding domain of HMG-CoA reductase [56544] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [56545] (9 PDB entries)
1. Domains for 1dq8:
  1. Domain d1dq8a4: 1dq8 A:439-586,A:704-863 [42589]
    Other proteins in same PDB: d1dq8a1, d1dq8b1, d1dq8c1, d1dq8d1
    complexed with coa, dtt, mah
  2. Domain d1dq8b4: 1dq8 B:461-586,B:704-865 [42590]
    Other proteins in same PDB: d1dq8a1, d1dq8b1, d1dq8c1, d1dq8d1
    complexed with coa, dtt, mah
  3. Domain d1dq8c4: 1dq8 C:464-586,C:704-865 [42591]
    Other proteins in same PDB: d1dq8a1, d1dq8b1, d1dq8c1, d1dq8d1
    complexed with coa, dtt, mah
  4. Domain d1dq8d4: 1dq8 D:458-586,D:704-864 [42592]
    Other proteins in same PDB: d1dq8a1, d1dq8b1, d1dq8c1, d1dq8d1
    complexed with coa, dtt, mah
2. Domains for 1dq9:
  1. Domain d1dq9a4: 1dq9 A:461-586,A:704-865 [42593]
    Other proteins in same PDB: d1dq9a1, d1dq9b1, d1dq9c1, d1dq9d1
    complexed with hmg
  2. Domain d1dq9b4: 1dq9 B:460-586,B:704-864 [42594]
    Other proteins in same PDB: d1dq9a1, d1dq9b1, d1dq9c1, d1dq9d1
    complexed with hmg
  3. Domain d1dq9c4: 1dq9 C:460-586,C:704-866 [42595]
    Other proteins in same PDB: d1dq9a1, d1dq9b1, d1dq9c1, d1dq9d1
    complexed with hmg
  4. Domain d1dq9d4: 1dq9 D:453-586,D:704-865 [42596]
    Other proteins in same PDB: d1dq9a1, d1dq9b1, d1dq9c1, d1dq9d1
    complexed with hmg
3. Domains for 1dqa:
  1. Domain d1dqaa4: 1dqa A:462-586,A:704-870 [42585]
    Other proteins in same PDB: d1dqaa1, d1dqab1, d1dqac1, d1dqad1
    complexed with coa, mah, nap
  2. Domain d1dqab4: 1dqa B:462-586,B:704-866 [42586]
    Other proteins in same PDB: d1dqaa1, d1dqab1, d1dqac1, d1dqad1
    complexed with coa, mah, nap
  3. Domain d1dqac4: 1dqa C:468-586,C:704-871 [42587]
    Other proteins in same PDB: d1dqaa1, d1dqab1, d1dqac1, d1dqad1
    complexed with coa, mah, nap
  4. Domain d1dqad4: 1dqa D:477-586,D:704-872 [42588]
    Other proteins in same PDB: d1dqaa1, d1dqab1, d1dqac1, d1dqad1
    complexed with coa, mah, nap
4. Domains for 1hw8:
  1. Domain d1hw8a2: 1hw8 A:441-586,A:704-861 [61299]
    Other proteins in same PDB: d1hw8a1, d1hw8b1, d1hw8c1, d1hw8d1
    complexed with 114, adp
  2. Domain d1hw8b2: 1hw8 B:443-586,B:704-860 [61301]
    Other proteins in same PDB: d1hw8a1, d1hw8b1, d1hw8c1, d1hw8d1
    complexed with 114, adp
  3. Domain d1hw8c2: 1hw8 C:488-586,C:704-860 [61303]
    Other proteins in same PDB: d1hw8a1, d1hw8b1, d1hw8c1, d1hw8d1
    complexed with 114, adp
  4. Domain d1hw8d2: 1hw8 D:488-586,D:704-859 [61305]
    Other proteins in same PDB: d1hw8a1, d1hw8b1, d1hw8c1, d1hw8d1
    complexed with 114, adp
5. Domains for 1hw9:
  1. Domain d1hw9a2: 1hw9 A:442-586,A:704-860 [61307]
    Other proteins in same PDB: d1hw9a1, d1hw9b1, d1hw9c1, d1hw9d1
    complexed with adp, sim
  2. Domain d1hw9b2: 1hw9 B:463-586,B:704-860 [61309]
    Other proteins in same PDB: d1hw9a1, d1hw9b1, d1hw9c1, d1hw9d1
    complexed with adp, sim
  3. Domain d1hw9c2: 1hw9 C:463-586,C:704-860 [61311]
    Other proteins in same PDB: d1hw9a1, d1hw9b1, d1hw9c1, d1hw9d1
    complexed with adp, sim
  4. Domain d1hw9d2: 1hw9 D:464-586,D:704-859 [61313]
    Other proteins in same PDB: d1hw9a1, d1hw9b1, d1hw9c1, d1hw9d1
    complexed with adp, sim
6. Domains for 1hwi:
  1. Domain d1hwia2: 1hwi A:462-586,A:704-862 [61315]
    Other proteins in same PDB: d1hwia1, d1hwib1, d1hwic1, d1hwid1
    complexed with 115, adp
  2. Domain d1hwib2: 1hwi B:462-586,B:704-860 [61317]
    Other proteins in same PDB: d1hwia1, d1hwib1, d1hwic1, d1hwid1
    complexed with 115, adp
  3. Domain d1hwic2: 1hwi C:489-586,C:704-862 [61319]
    Other proteins in same PDB: d1hwia1, d1hwib1, d1hwic1, d1hwid1
    complexed with 115, adp
  4. Domain d1hwid2: 1hwi D:487-586,D:704-860 [61321]
    Other proteins in same PDB: d1hwia1, d1hwib1, d1hwic1, d1hwid1
    complexed with 115, adp
7. Domains for 1hwj:
  1. Domain d1hwja2: 1hwj A:442-586,A:704-861 [61323]
    Other proteins in same PDB: d1hwja1, d1hwjb1, d1hwjc1, d1hwjd1
    complexed with 116, adp
  2. Domain d1hwjb2: 1hwj B:463-586,B:704-860 [61325]
    Other proteins in same PDB: d1hwja1, d1hwjb1, d1hwjc1, d1hwjd1
    complexed with 116, adp
  3. Domain d1hwjc2: 1hwj C:442-586,C:704-860 [61327]
    Other proteins in same PDB: d1hwja1, d1hwjb1, d1hwjc1, d1hwjd1
    complexed with 116, adp
  4. Domain d1hwjd2: 1hwj D:462-586,D:704-860 [61329]
    Other proteins in same PDB: d1hwja1, d1hwjb1, d1hwjc1, d1hwjd1
    complexed with 116, adp
8. Domains for 1hwk:
  1. Domain d1hwka2: 1hwk A:442-586,A:704-861 [61331]
    Other proteins in same PDB: d1hwka1, d1hwkb1, d1hwkc1, d1hwkd1
    complexed with 117, adp
  2. Domain d1hwkb2: 1hwk B:463-586,B:704-860 [61333]
    Other proteins in same PDB: d1hwka1, d1hwkb1, d1hwkc1, d1hwkd1
    complexed with 117, adp
  3. Domain d1hwkc2: 1hwk C:462-586,C:704-860 [61335]
    Other proteins in same PDB: d1hwka1, d1hwkb1, d1hwkc1, d1hwkd1
    complexed with 117, adp
  4. Domain d1hwkd2: 1hwk D:463-586,D:704-860 [61337]
    Other proteins in same PDB: d1hwka1, d1hwkb1, d1hwkc1, d1hwkd1
    complexed with 117, adp
9. Domains for 1hwl:
  1. Domain d1hwla2: 1hwl A:442-586,A:704-860 [61339]
    Other proteins in same PDB: d1hwla1, d1hwlb1, d1hwlc1, d1hwld1
    complexed with adp, fbi
  2. Domain d1hwlb2: 1hwl B:463-586,B:704-860 [61341]
    Other proteins in same PDB: d1hwla1, d1hwlb1, d1hwlc1, d1hwld1
    complexed with adp, fbi
  3. Domain d1hwlc2: 1hwl C:463-586,C:704-860 [61343]
    Other proteins in same PDB: d1hwla1, d1hwlb1, d1hwlc1, d1hwld1
    complexed with adp, fbi
  4. Domain d1hwld2: 1hwl D:479-586,D:704-860 [61345]
    Other proteins in same PDB: d1hwla1, d1hwlb1, d1hwlc1, d1hwld1
    complexed with adp, fbi
Pseudomonas mevalonii [TaxId:32044] [56546] (11 PDB entries)
Uniprot P13702 4-377
1. Domains for 1qax:
  1. Domain d1qaxa2: 1qax A:4-110,A:221-428 [42597]
    Other proteins in same PDB: d1qaxa1, d1qaxb1
    complexed with hmg, nad
  2. Domain d1qaxb2: 1qax B:504-610,B:721-875 [42598]
    Other proteins in same PDB: d1qaxa1, d1qaxb1
    complexed with hmg, nad
2. Domains for 1qay:
  1. Domain d1qaya2: 1qay A:4-110,A:221-387 [42599]
    Other proteins in same PDB: d1qaya1, d1qayb1
    complexed with mev, nad
  2. Domain d1qayb2: 1qay B:504-610,B:721-877 [42600]
    Other proteins in same PDB: d1qaya1, d1qayb1
    complexed with mev, nad
3. Domains for 1r31:
  1. Domain d1r31a2: 1r31 A:3-110,A:221-378 [96898]
    Other proteins in same PDB: d1r31a1, d1r31b1
    complexed with coa, mev, so4
  2. Domain d1r31b2: 1r31 B:503-610,B:721-877 [96900]
    Other proteins in same PDB: d1r31a1, d1r31b1
    complexed with coa, mev, so4
4. Domains for 1r7i:
  1. Domain d1r7ia2: 1r7i A:3-110,A:221-374 [97199]
    Other proteins in same PDB: d1r7ia1, d1r7ib1
    complexed with gol, so4
  2. Domain d1r7ib2: 1r7i B:503-610,B:721-877 [97201]
    Other proteins in same PDB: d1r7ia1, d1r7ib1
    complexed with gol, so4
5. Domains for 1t02:
  1. Domain d1t02a2: 1t02 A:4-110,A:221-374 [106191]
    Other proteins in same PDB: d1t02a1, d1t02b1
    complexed with lva, so4
  2. Domain d1t02b2: 1t02 B:4-110,B:221-374 [106193]
    Other proteins in same PDB: d1t02a1, d1t02b1
    complexed with lva, so4
6. Domains for 4i4b:
  1. Domain d4i4ba1: 4i4b A:3-110,A:221-421 [222895]
    Other proteins in same PDB: d4i4ba2, d4i4bb2
    automated match to d1qaxa2
    complexed with 1co, 1cv, gol, nad, so4
  2. Domain d4i4bb1: 4i4b B:503-610,B:721-878 [222897]
    Other proteins in same PDB: d4i4ba2, d4i4bb2
    automated match to d1r31a2
    complexed with 1co, 1cv, gol, nad, so4
7. Domains for 4i56:
  1. Domain d4i56a1: 4i56 A:3-110,A:221-375 [222930]
    Other proteins in same PDB: d4i56a2, d4i56b2
    automated match to d1r31a2
    complexed with 1cz, gol, so4
  2. Domain d4i56b1: 4i56 B:503-610,B:721-878 [222932]
    Other proteins in same PDB: d4i56a2, d4i56b2
    automated match to d1r31a2
    complexed with 1cz, gol, so4
8. Domains for 4i64:
  1. Domain d4i64a1: 4i64 A:3-110,A:221-375 [222949]
    Other proteins in same PDB: d4i64a2, d4i64b2
    automated match to d1r31a2
    complexed with so4
  2. Domain d4i64b1: 4i64 B:503-610,B:721-878 [222951]
    Other proteins in same PDB: d4i64a2, d4i64b2
    automated match to d1r31a2
    complexed with so4
9. Domains for 4i6a:
  1. Domain d4i6aa1: 4i6a A:3-110,A:221-378 [222953]
    Other proteins in same PDB: d4i6aa2, d4i6ab2
    automated match to d1r31a2
    complexed with hmg, so4
  2. Domain d4i6ab1: 4i6a B:503-610,B:721-878 [222955]
    Other proteins in same PDB: d4i6aa2, d4i6ab2
    automated match to d1r31a2
    complexed with hmg, so4
10. Domains for 4i6w:
  1. Domain d4i6wa1: 4i6w A:3-110,A:221-375 [222962]
    Other proteins in same PDB: d4i6wa2, d4i6wb2
    automated match to d1r31a2
    complexed with 1co, gol, so4
  2. Domain d4i6wb1: 4i6w B:503-610,B:721-878 [222964]
    Other proteins in same PDB: d4i6wa2, d4i6wb2
    automated match to d1r31a2
    complexed with 1co, gol, so4
11. Domains for 4i6y:
  1. Domain d4i6ya1: 4i6y A:3-110,A:221-376 [222966]
    Other proteins in same PDB: d4i6ya2, d4i6yb2
    automated match to d1r31a2
    complexed with gol, mev, no2, so4
  2. Domain d4i6yb1: 4i6y B:503-610,B:721-879 [222968]
    Other proteins in same PDB: d4i6ya2, d4i6yb2
    automated match to d1r31a2
    complexed with gol, mev, no2, so4

More info for Protein Substrate-binding domain of HMG-CoA reductase from d.179.1.1: Substrate-binding domain of HMG-CoA reductase

Timeline for Protein Substrate-binding domain of HMG-CoA reductase from d.179.1.1: Substrate-binding domain of HMG-CoA reductase:

Protein Substrate-binding domain of HMG-CoA reductase from d.179.1.1: Substrate-binding domain of HMG-CoA reductase first appeared (with stable ids) in SCOP 1.55
Protein Substrate-binding domain of HMG-CoA reductase from d.179.1.1: Substrate-binding domain of HMG-CoA reductase appears in SCOPe 2.07