SCOPe 2.05: Family d.177.1.1: FAH

Lineage for Family d.177.1.1: FAH

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.177: FAH [56528] (1 superfamily)
   unusual fold; contains 3 layers of beta-sheet structure

4. Superfamily d.177.1: FAH [56529] (2 families)

5. Family d.177.1.1: FAH [56530] (7 proteins)
   automatically mapped to Pfam PF01557

Proteins:

1. 2-keto-4-pentenoate hydratase MhpD [111274] (1 species)

   • Species Escherichia coli [TaxId:562] [111275] (1 PDB entry)
     Uniprot P77608

2. 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpcE [64459] (1 species)
   duplication: tandem repeat of two FAH domains

   • Species Escherichia coli [TaxId:562] [64460] (2 PDB entries)

3. FAHD1 (Flj36880, YISKL) [118170] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [118171] (1 PDB entry)
     Uniprot Q6P587

4. Fumarylacetoacetate hydrolase, FAH, C-terminal domain [63432] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [56532] (5 PDB entries)

5. Hypothetical protein Ynl168c [111272] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [111273] (1 PDB entry)
     Uniprot P53889

6. Putative isomerase YcgM [90070] (1 species)

   • Species Escherichia coli [TaxId:562] [90071] (1 PDB entry)

7. automated matches [191123] (2 species)
   not a true protein

   1. Species Escherichia coli K-12 [TaxId:83333] [189200] (1 PDB entry)

   2. Species Yersinia pestis [TaxId:214092] [190007] (1 PDB entry)

More info for Family d.177.1.1: FAH

Timeline for Family d.177.1.1: FAH:

• Family d.177.1.1: FAH first appeared (with stable ids) in SCOP 1.55, called Family d.177.1.1: Fumarylacetoacetate hydrolase, FAH
  
• Family d.177.1.1: FAH appears in SCOPe 2.04
  
• Family d.177.1.1: FAH appears in SCOPe 2.06
  
• Family d.177.1.1: FAH appears in the current release, SCOPe 2.08