Lineage for Family d.166.1.1: ADP-ribosylating toxins

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.166: ADP-ribosylation [56398] (1 superfamily)
    unusual fold
  4. Superfamily d.166.1: ADP-ribosylation [56399] (8 families) (S)
  5. Family d.166.1.1: ADP-ribosylating toxins [56400] (10 proteins)

Proteins:

  1. Anthrax toxin lethal factor, middle domain [69845] (1 species)
    includes an all-alpha insert subdomain
  2. Cholera toxin [56410] (1 species)
  3. Diphtheria toxin, N-terminal domain [56404] (1 species)
  4. Enzymatic component (Ia) of iota-toxin [82812] (1 species)
    mammalian-targeted relative of VIP2; C-terminal domain is catalytic, N-terminal domain interacts with Ib (binding component)
  5. Exoenzyme c3 [56414] (4 species)
    1. Species Clostridium botulinum C bacteriophage [TaxId:12336] [118161] (2 PDB entries)
      Uniprot Q00901 44-244
    2. Species Clostridium botulinum [TaxId:1491] [56415] (6 PDB entries)
      Uniprot P15879 41-251
    3. Species Clostridium limosum [TaxId:1536] [188401] (1 PDB entry)
    4. Species Staphylococcus aureus [TaxId:1280] [103338] (2 PDB entries)
  6. Exotoxin A, C-terminal domain [56406] (1 species)
  7. Heat-labile toxin, A-chain [56401] (2 species)
    1. Species Escherichia coli, type IB [TaxId:562] [56402] (9 PDB entries)
    2. Species Escherichia coli, type IIB [TaxId:562] [56403] (1 PDB entry)
  8. Pertussis toxin, S1 subunit [56408] (1 species)
  9. Vegetative insecticidal protein 2 (VIP2) [56412] (1 species)
    duplication: consists of two domains of this fold, the second of which is catalytic
  10. automated matches [190133] (8 species)
    not a true protein
    1. Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [234339] (15 PDB entries)
    2. Species Bordetella pertussis [TaxId:520] [386834] (1 PDB entry)
    3. Species Clostridium botulinum [346391] (1 PDB entry)
    4. Species Clostridium botulinum [TaxId:1491] [187018] (9 PDB entries)
    5. Species Clostridium botulinum [TaxId:29342] [186934] (1 PDB entry)
    6. Species Clostridium perfringens [TaxId:1502] [234554] (8 PDB entries)
    7. Species Pseudomonas aeruginosa [TaxId:287] [186856] (5 PDB entries)
    8. Species Clostridioides difficile [TaxId:1496] [420073] (3 PDB entries)

More info for Family d.166.1.1: ADP-ribosylating toxins

Timeline for Family d.166.1.1: ADP-ribosylating toxins: