SCOP 1.71: Protein: Eukaryotic DNA topoisomerase I, catalytic core

Lineage for Protein: Eukaryotic DNA topoisomerase I, catalytic core

Root: SCOP 1.71
Class d: Alpha and beta proteins (a+b) [53931] (286 folds)
Fold d.163: DNA breaking-rejoining enzymes [56348] (1 superfamily)
core: alpha3-beta3-alpha4; one side of beta-sheet is exposed
Superfamily d.163.1: DNA breaking-rejoining enzymes [56349] (2 families)
Family d.163.1.2: Eukaryotic DNA topoisomerase I, catalytic core [56361] (1 protein)
Protein Eukaryotic DNA topoisomerase I, catalytic core [56362] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [56363] (11 PDB entries)
1. Domain for 1a31:
  - Domain d1a31a1: 1a31 A:431-626,A:720-765 [42170]
    Other proteins in same PDB: d1a31a2
    protein/DNA complex; complexed with 5iu
2. Domain for 1a35:
  - Domain d1a35a1: 1a35 A:431-635,A:713-765 [42171]
    Other proteins in same PDB: d1a35a2
    protein/DNA complex; complexed with bru; mutant
3. Domain for 1a36:
  - Domain d1a36a2: 1a36 A:431-633,A:713-765 [42173]
    Other proteins in same PDB: d1a36a1, d1a36a3
    protein/DNA complex; mutant
4. Domain for 1ej9:
  - Domain d1ej9a1: 1ej9 A:431-633,A:714-765 [42172]
    Other proteins in same PDB: d1ej9a2
    protein/DNA complex; mutant
5. Domain for 1k4s:
  - Domain d1k4sa1: 1k4s A:431-632,A:708-765 [77261]
    Other proteins in same PDB: d1k4sa2
    complexed with ido, ptr, spt
6. Domain for 1k4t:
  - Domain d1k4ta2: 1k4t A:431-640,A:713-765 [77264]
    Other proteins in same PDB: d1k4ta1, d1k4ta3
    complexed with hg, pg4, ptr, tgp, ttc, ttg
7. Domain for 1lpq:
  - Domain d1lpqa2: 1lpq A:431-633,A:713-765 [74175]
    Other proteins in same PDB: d1lpqa1, d1lpqa3
    complexed with 8og; mutant
8. Domain for 1nh3:
  - Domain d1nh3a1: 1nh3 A:431-626,A:719-765 [85710]
    Other proteins in same PDB: d1nh3a2
    complexed with car, gng, ptr, ubb
9. Domain for 1r49:
  - Domain d1r49a2: 1r49 A:431-633,A:719-765 [96984]
    Other proteins in same PDB: d1r49a1, d1r49a3
    mutant
10. Domain for 1rr8:
  - Domain d1rr8c1: 1rr8 C:431-608,C:708-765 [105076]
    Other proteins in same PDB: d1rr8c2
    complexed with ttc, ttg; mutant
11. Domain for 1rrj:
  - Domain d1rrja2: 1rrj A:431-635,A:713-765 [105079]
    Other proteins in same PDB: d1rrja1, d1rrja3
    complexed with ttc, ttg; mutant
Vaccinia virus [TaxId:10245] [56364] (1 PDB entry)
- Domain for 1a41:
  - Domain d1a41__: 1a41 - [42174]
    complexed with so4

More info for Protein Eukaryotic DNA topoisomerase I, catalytic core from d.163.1.2: Eukaryotic DNA topoisomerase I, catalytic core

Timeline for Protein Eukaryotic DNA topoisomerase I, catalytic core from d.163.1.2: Eukaryotic DNA topoisomerase I, catalytic core:

Protein Eukaryotic DNA topoisomerase I, catalytic core from d.163.1.2: Eukaryotic DNA topoisomerase I, catalytic core first appeared (with stable ids) in SCOP 1.55
Protein Eukaryotic DNA topoisomerase I, catalytic core from d.163.1.2: Eukaryotic DNA topoisomerase I, catalytic core appears in SCOP 1.69
Protein Eukaryotic DNA topoisomerase I, catalytic core from d.163.1.2: Eukaryotic DNA topoisomerase I, catalytic core appears in SCOP 1.73
Protein Eukaryotic DNA topoisomerase I, catalytic core from d.163.1.2: Eukaryotic DNA topoisomerase I, catalytic core appears in the current release, SCOPe 2.08