SCOPe 2.07: Protein: Malate dehydrogenase

Lineage for Protein: Malate dehydrogenase

Root: SCOPe 2.07
Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
unusual fold, defines family
Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)
Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
automatically mapped to Pfam PF02866
Protein Malate dehydrogenase [56329] (12 species)

Species:

Aquaspirillum arcticum [TaxId:87645] [56336] (3 PDB entries)
1. Domain for 1b8p:
  - Domain d1b8pa2: 1b8p A:159-329 [42114]
    Other proteins in same PDB: d1b8pa1
2. Domain for 1b8u:
  - Domain d1b8ua2: 1b8u A:159-329 [42116]
    Other proteins in same PDB: d1b8ua1
    complexed with nad, oaa
3. Domain for 1b8v:
  - Domain d1b8va2: 1b8v A:159-329 [42115]
    Other proteins in same PDB: d1b8va1
    complexed with nad
Chlorobium tepidum [TaxId:1097] [69841] (1 PDB entry)
- Domains for 1gv0:
  1. Domain d1gv0a2: 1gv0 A:143-305 [65595]
    Other proteins in same PDB: d1gv0a1, d1gv0b1
    complexed with nad
  2. Domain d1gv0b2: 1gv0 B:143-305 [65597]
    Other proteins in same PDB: d1gv0a1, d1gv0b1
    complexed with nad
Chlorobium vibrioforme [TaxId:1098] [69842] (2 PDB entries)
1. Domains for 1guz:
  1. Domain d1guza2: 1guz A:143-305 [65587]
    Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
    complexed with nad
  2. Domain d1guzb2: 1guz B:143-305 [65589]
    Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
    complexed with nad
  3. Domain d1guzc2: 1guz C:143-305 [65591]
    Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
    complexed with nad
  4. Domain d1guzd2: 1guz D:143-305 [65593]
    Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
    complexed with nad
2. Domains for 1gv1:
  1. Domain d1gv1a2: 1gv1 A:143-305 [65599]
    Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
  2. Domain d1gv1b2: 1gv1 B:143-299 [65601]
    Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
  3. Domain d1gv1c2: 1gv1 C:143-305 [65603]
    Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
  4. Domain d1gv1d2: 1gv1 D:143-302 [65605]
    Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
Chloroflexus aurantiacus [TaxId:1108] [69840] (7 PDB entries)
Uniprot P80040
1. Domains for 1guy:
  1. Domain d1guya2: 1guy A:144-306 [65583]
    Other proteins in same PDB: d1guya1, d1guyc1
    complexed with cd, nad
  2. Domain d1guyc2: 1guy C:144-306 [65585]
    Other proteins in same PDB: d1guya1, d1guyc1
    complexed with cd, nad
2. Domains for 1ur5:
  1. Domain d1ur5a2: 1ur5 A:144-308 [99808]
    Other proteins in same PDB: d1ur5a1, d1ur5c1
    complexed with cd, cl, na, nad
  2. Domain d1ur5c2: 1ur5 C:144-309 [99810]
    Other proteins in same PDB: d1ur5a1, d1ur5c1
    complexed with cd, cl, na, nad
3. Domains for 1uxg:
  1. Domain d1uxga2: 1uxg A:144-307 [108101]
    Other proteins in same PDB: d1uxga1, d1uxgb1
    complexed with fum, nad; mutant
  2. Domain d1uxgb2: 1uxg B:144-307 [108103]
    Other proteins in same PDB: d1uxga1, d1uxgb1
    complexed with fum, nad; mutant
4. Domains for 1uxh:
  1. Domain d1uxha2: 1uxh A:144-307 [108105]
    Other proteins in same PDB: d1uxha1, d1uxhb1
    complexed with fum, nad; mutant
  2. Domain d1uxhb2: 1uxh B:144-307 [108107]
    Other proteins in same PDB: d1uxha1, d1uxhb1
    complexed with fum, nad; mutant
5. Domains for 1uxi:
  1. Domain d1uxia2: 1uxi A:144-307 [108109]
    Other proteins in same PDB: d1uxia1, d1uxib1
    complexed with fum, na, nad; mutant
  2. Domain d1uxib2: 1uxi B:144-307 [108111]
    Other proteins in same PDB: d1uxia1, d1uxib1
    complexed with fum, na, nad; mutant
6. Domains for 1uxj:
  1. Domain d1uxja2: 1uxj A:144-307 [108113]
    Other proteins in same PDB: d1uxja1, d1uxjc1
    complexed with cd, cl, na, nad; mutant
  2. Domain d1uxjc2: 1uxj C:144-307 [108115]
    Other proteins in same PDB: d1uxja1, d1uxjc1
    complexed with cd, cl, na, nad; mutant
7. Domains for 1uxk:
  1. Domain d1uxka2: 1uxk A:144-307 [108117]
    Other proteins in same PDB: d1uxka1, d1uxkc1
    complexed with cd, cl, na, nad; mutant
  2. Domain d1uxkc2: 1uxk C:144-307 [108119]
    Other proteins in same PDB: d1uxka1, d1uxkc1
    complexed with cd, cl, na, nad; mutant
Chloroflexus sp. [TaxId:480224] [236535] (1 PDB entry)
- Domains for 4cl3:
  1. Domain d4cl3a2: 4cl3 A:144-309 [236537]
    Other proteins in same PDB: d4cl3a1, d4cl3d1
    automated match to d1guya2
    complexed with act, cd, cl, peg
  2. Domain d4cl3d2: 4cl3 D:144-309 [236538]
    Other proteins in same PDB: d4cl3a1, d4cl3d1
    automated match to d1guya2
    complexed with act, cd, cl, peg
Escherichia coli [TaxId:562] [56333] (4 PDB entries)
1. Domain for 1emd:
  - Domain d1emda2: 1emd A:146-312 [42103]
    Other proteins in same PDB: d1emda1
    complexed with cit, nad
2. Domains for 1ib6:
  1. Domain d1ib6a2: 1ib6 A:146-312 [62147]
    Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
    complexed with nad, so4
  2. Domain d1ib6b2: 1ib6 B:146-312 [62149]
    Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
    complexed with nad, so4
  3. Domain d1ib6c2: 1ib6 C:146-312 [62151]
    Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
    complexed with nad, so4
  4. Domain d1ib6d2: 1ib6 D:146-312 [62153]
    Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
    complexed with nad, so4
3. Domains for 1ie3:
  1. Domain d1ie3a2: 1ie3 A:146-312 [62305]
    Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
    complexed with nad, pyr
  2. Domain d1ie3b2: 1ie3 B:146-312 [62307]
    Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
    complexed with nad, pyr
  3. Domain d1ie3c2: 1ie3 C:146-312 [62309]
    Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
    complexed with nad, pyr
  4. Domain d1ie3d2: 1ie3 D:146-312 [62311]
    Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
    complexed with nad, pyr
4. Domain for 2cmd:
  - Domain d2cmda2: 2cmd A:146-312 [42102]
    Other proteins in same PDB: d2cmda1
    complexed with cit
Flaveria bidentis, chloroplast [TaxId:4224] [56332] (1 PDB entry)
- Domain for 1civ:
  - Domain d1civa2: 1civ A:194-385 [42101]
    Other proteins in same PDB: d1civa1
    complexed with nap
Haloarcula marismortui [TaxId:2238] [56335] (6 PDB entries)
1. Domains for 1d3a:
  1. Domain d1d3aa2: 1d3a A:163-330 [42110]
    Other proteins in same PDB: d1d3aa1, d1d3ab1
    complexed with cl, na
  2. Domain d1d3ab2: 1d3a B:163-330 [42111]
    Other proteins in same PDB: d1d3aa1, d1d3ab1
    complexed with cl, na
2. Domains for 1gt2:
  1. Domain d1gt2a4: 1gt2 A:163-330 [302444]
    Other proteins in same PDB: d1gt2a3, d1gt2b3
    automated match to d1o6za2
    complexed with cl, na, nad; mutant
  2. Domain d1gt2b4: 1gt2 B:163-330 [302446]
    Other proteins in same PDB: d1gt2a3, d1gt2b3
    automated match to d1o6za2
    complexed with cl, na, nad; mutant
3. Domains for 1hlp:
  1. Domain d1hlpa2: 1hlp A:163-328 [42112]
    Other proteins in same PDB: d1hlpa1, d1hlpb1
    complexed with nad
  2. Domain d1hlpb2: 1hlp B:163-328 [42113]
    Other proteins in same PDB: d1hlpa1, d1hlpb1
    complexed with nad
4. Domains for 1o6z:
  1. Domain d1o6za2: 1o6z A:163-330 [81108]
    Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
    complexed with cl, nad; mutant
  2. Domain d1o6zb2: 1o6z B:163-330 [81110]
    Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
    complexed with cl, nad; mutant
  3. Domain d1o6zc2: 1o6z C:163-330 [81112]
    Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
    complexed with cl, nad; mutant
  4. Domain d1o6zd2: 1o6z D:163-330 [81114]
    Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
    complexed with cl, nad; mutant
5. Domains for 2hlp:
  1. Domain d2hlpa2: 2hlp A:163-330 [42108]
    Other proteins in same PDB: d2hlpa1, d2hlpb1
    complexed with cl, na; mutant
  2. Domain d2hlpb2: 2hlp B:163-330 [42109]
    Other proteins in same PDB: d2hlpa1, d2hlpb1
    complexed with cl, na; mutant
6. Domains for 2x0r:
  1. Domain d2x0ra2: 2x0r A:163-330 [169771]
    Other proteins in same PDB: d2x0ra1, d2x0rb1
    complexed with cl, na, nad; mutant
  2. Domain d2x0rb2: 2x0r B:163-330 [169773]
    Other proteins in same PDB: d2x0ra1, d2x0rb1
    complexed with cl, na, nad; mutant
Pig (Sus scrofa) [TaxId:9823] [56330] (3 PDB entries)
1. Domains for 1mld:
  1. Domain d1mlda2: 1mld A:145-313 [42089]
    Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
    complexed with cit
  2. Domain d1mldb2: 1mld B:145-313 [42090]
    Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
    complexed with cit
  3. Domain d1mldc2: 1mld C:145-313 [42091]
    Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
    complexed with cit
  4. Domain d1mldd2: 1mld D:145-313 [42092]
    Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
    complexed with cit
2. Domains for 4mdh:
  1. Domain d4mdha2: 4mdh A:155-333 [42095]
    Other proteins in same PDB: d4mdha1, d4mdhb1
    complexed with nad, so4
  2. Domain d4mdhb2: 4mdh B:155-333 [42096]
    Other proteins in same PDB: d4mdha1, d4mdhb1
    complexed with nad, so4
3. Domains for 5mdh:
  1. Domain d5mdha2: 5mdh A:155-333 [42093]
    Other proteins in same PDB: d5mdha1, d5mdhb1
    complexed with mak, nad
  2. Domain d5mdhb2: 5mdh B:155-333 [42094]
    Other proteins in same PDB: d5mdha1, d5mdhb1
    complexed with mak, nad
Sorghum (Sorghum vulgare), chloroplast [TaxId:4558] [56331] (1 PDB entry)
- Domains for 7mdh:
  1. Domain d7mdha2: 7mdh A:198-385 [42097]
    Other proteins in same PDB: d7mdha1, d7mdhb1, d7mdhc1, d7mdhd1
    complexed with zn
  2. Domain d7mdhb2: 7mdh B:198-386 [42098]
    Other proteins in same PDB: d7mdha1, d7mdhb1, d7mdhc1, d7mdhd1
    complexed with zn
  3. Domain d7mdhc2: 7mdh C:198-384 [42099]
    Other proteins in same PDB: d7mdha1, d7mdhb1, d7mdhc1, d7mdhd1
    complexed with zn
  4. Domain d7mdhd2: 7mdh D:198-381 [42100]
    Other proteins in same PDB: d7mdha1, d7mdhb1, d7mdhc1, d7mdhd1
    complexed with zn
Thermus flavus [TaxId:274] [56334] (2 PDB entries)
1. Domains for 1bdm:
  1. Domain d1bdma2: 1bdm A:155-332 [42104]
    Other proteins in same PDB: d1bdma1, d1bdmb1
    complexed with nax; mutant
  2. Domain d1bdmb2: 1bdm B:155-332 [42105]
    Other proteins in same PDB: d1bdma1, d1bdmb1
    complexed with nax; mutant
2. Domains for 1bmd:
  1. Domain d1bmda2: 1bmd A:155-332 [42106]
    Other proteins in same PDB: d1bmda1, d1bmdb1
    complexed with nad
  2. Domain d1bmdb2: 1bmd B:155-332 [42107]
    Other proteins in same PDB: d1bmda1, d1bmdb1
    complexed with nad
Thermus thermophilus [TaxId:274] [82806] (7 PDB entries)
identical sequence to that from the Thermus flavus enzyme
1. Domains for 1iz9:
  1. Domain d1iz9a2: 1iz9 A:155-327 [76985]
    Other proteins in same PDB: d1iz9a1, d1iz9b1
  2. Domain d1iz9b2: 1iz9 B:155-327 [76987]
    Other proteins in same PDB: d1iz9a1, d1iz9b1
2. Domains for 1wze:
  1. Domain d1wzea2: 1wze A:154-332 [121496]
    Other proteins in same PDB: d1wzea1, d1wzeb1
    automated match to d1y7ta2
    complexed with nad
  2. Domain d1wzeb2: 1wze B:154-332 [121498]
    Other proteins in same PDB: d1wzea1, d1wzeb1
    automated match to d1y7ta2
    complexed with nad
3. Domains for 1wzi:
  1. Domain d1wzia2: 1wzi A:154-332 [121504]
    Other proteins in same PDB: d1wzia1, d1wzib1
    automated match to d1y7ta2
    complexed with ndp
  2. Domain d1wzib2: 1wzi B:154-332 [121506]
    Other proteins in same PDB: d1wzia1, d1wzib1
    automated match to d1y7ta2
    complexed with ndp
4. Domains for 1y7t:
  1. Domain d1y7ta2: 1y7t A:154-332 [122719]
    Other proteins in same PDB: d1y7ta1, d1y7tb1
    automated match to d1iz9a2
    complexed with ndp, trs
  2. Domain d1y7tb2: 1y7t B:154-332 [122721]
    Other proteins in same PDB: d1y7ta1, d1y7tb1
    automated match to d1iz9a2
    complexed with ndp, trs
5. Domains for 2cvq:
  1. Domain d2cvqa2: 2cvq A:154-332 [130886]
    Other proteins in same PDB: d2cvqa1, d2cvqb1
    automated match to d1iz9a2
    complexed with ndp, trs
  2. Domain d2cvqb2: 2cvq B:154-332 [130888]
    Other proteins in same PDB: d2cvqa1, d2cvqb1
    automated match to d1iz9a2
    complexed with ndp, trs
6. Domains for 4kde:
  1. Domain d4kdea2: 4kde A:155-327 [236586]
    Other proteins in same PDB: d4kdea1, d4kdea3, d4kdeb1, d4kdeb3
    automated match to d1wzea2
  2. Domain d4kdeb2: 4kde B:155-327 [236589]
    Other proteins in same PDB: d4kdea1, d4kdea3, d4kdeb1, d4kdeb3
    automated match to d1wzea2
7. Domains for 4kdf:
  1. Domain d4kdfa2: 4kdf A:155-326 [236591]
    Other proteins in same PDB: d4kdfa1, d4kdfb1, d4kdfc1, d4kdfd1
    automated match to d1wzea2
    complexed with so4
  2. Domain d4kdfd2: 4kdf D:155-326 [236587]
    Other proteins in same PDB: d4kdfa1, d4kdfb1, d4kdfc1, d4kdfd1
    automated match to d1wzea2
    complexed with so4

More info for Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

Timeline for Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain:

Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain first appeared (with stable ids) in SCOP 1.55
Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain appears in SCOPe 2.06
Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain appears in the current release, SCOPe 2.08