Lineage for Protein: Malate dehydrogenase

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1938734Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 1938735Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families) (S)
  5. 1938736Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
    automatically mapped to Pfam PF02866
  6. 1938965Protein Malate dehydrogenase [56329] (12 species)

Species:

  1. 1938966Aquaspirillum arcticum [TaxId:87645] [56336] (3 PDB entries)
    1. Domain for 1b8p:
    2. Domain for 1b8u:
    3. Domain for 1b8v:
  2. 1938970Chlorobium tepidum [TaxId:1097] [69841] (1 PDB entry)
  3. 1938973Chlorobium vibrioforme [TaxId:1098] [69842] (2 PDB entries)
    1. Domains for 1guz:
      1. 1938974Domain d1guza2: 1guz A:143-305 [65587]
        Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
        complexed with nad
      2. 1938975Domain d1guzb2: 1guz B:143-305 [65589]
        Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
        complexed with nad
      3. 1938976Domain d1guzc2: 1guz C:143-305 [65591]
        Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
        complexed with nad
      4. 1938977Domain d1guzd2: 1guz D:143-305 [65593]
        Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
        complexed with nad
    2. Domains for 1gv1:
      1. 1938978Domain d1gv1a2: 1gv1 A:143-305 [65599]
        Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
      2. 1938979Domain d1gv1b2: 1gv1 B:143-299 [65601]
        Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
      3. 1938980Domain d1gv1c2: 1gv1 C:143-305 [65603]
        Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
      4. 1938981Domain d1gv1d2: 1gv1 D:143-302 [65605]
        Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
  4. 1938982Chloroflexus aurantiacus [TaxId:1108] [69840] (7 PDB entries)
    Uniprot P80040
    1. Domains for 1guy:
      1. 1938991Domain d1guya2: 1guy A:144-306 [65583]
        Other proteins in same PDB: d1guya1, d1guyc1
        complexed with cd, nad
      2. 1938992Domain d1guyc2: 1guy C:144-306 [65585]
        Other proteins in same PDB: d1guya1, d1guyc1
        complexed with cd, nad
    2. Domains for 1ur5:
      1. 1938985Domain d1ur5a2: 1ur5 A:144-308 [99808]
        Other proteins in same PDB: d1ur5a1, d1ur5c1
        complexed with cd, cl, na, nad
      2. 1938986Domain d1ur5c2: 1ur5 C:144-309 [99810]
        Other proteins in same PDB: d1ur5a1, d1ur5c1
        complexed with cd, cl, na, nad
    3. Domains for 1uxg:
      1. 1938989Domain d1uxga2: 1uxg A:144-307 [108101]
        Other proteins in same PDB: d1uxga1, d1uxgb1
        complexed with fum, nad; mutant
      2. 1938990Domain d1uxgb2: 1uxg B:144-307 [108103]
        Other proteins in same PDB: d1uxga1, d1uxgb1
        complexed with fum, nad; mutant
    4. Domains for 1uxh:
      1. 1938993Domain d1uxha2: 1uxh A:144-307 [108105]
        Other proteins in same PDB: d1uxha1, d1uxhb1
        complexed with fum, nad; mutant
      2. 1938994Domain d1uxhb2: 1uxh B:144-307 [108107]
        Other proteins in same PDB: d1uxha1, d1uxhb1
        complexed with fum, nad; mutant
    5. Domains for 1uxi:
      1. 1938995Domain d1uxia2: 1uxi A:144-307 [108109]
        Other proteins in same PDB: d1uxia1, d1uxib1
        complexed with fum, na, nad; mutant
      2. 1938996Domain d1uxib2: 1uxi B:144-307 [108111]
        Other proteins in same PDB: d1uxia1, d1uxib1
        complexed with fum, na, nad; mutant
    6. Domains for 1uxj:
      1. 1938983Domain d1uxja2: 1uxj A:144-307 [108113]
        Other proteins in same PDB: d1uxja1, d1uxjc1
        complexed with cd, cl, na, nad; mutant
      2. 1938984Domain d1uxjc2: 1uxj C:144-307 [108115]
        Other proteins in same PDB: d1uxja1, d1uxjc1
        complexed with cd, cl, na, nad; mutant
    7. Domains for 1uxk:
      1. 1938987Domain d1uxka2: 1uxk A:144-307 [108117]
        Other proteins in same PDB: d1uxka1, d1uxkc1
        complexed with cd, cl, na, nad; mutant
      2. 1938988Domain d1uxkc2: 1uxk C:144-307 [108119]
        Other proteins in same PDB: d1uxka1, d1uxkc1
        complexed with cd, cl, na, nad; mutant
  5. 1938997Chloroflexus sp. [TaxId:480224] [236535] (1 PDB entry)
  6. 1939000Escherichia coli [TaxId:562] [56333] (4 PDB entries)
    1. Domain for 1emd:
    2. Domains for 1ib6:
      1. 1939003Domain d1ib6a2: 1ib6 A:146-312 [62147]
        Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
        complexed with nad, so4
      2. 1939004Domain d1ib6b2: 1ib6 B:146-312 [62149]
        Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
        complexed with nad, so4
      3. 1939005Domain d1ib6c2: 1ib6 C:146-312 [62151]
        Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
        complexed with nad, so4
      4. 1939006Domain d1ib6d2: 1ib6 D:146-312 [62153]
        Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
        complexed with nad, so4
    3. Domains for 1ie3:
      1. 1939007Domain d1ie3a2: 1ie3 A:146-312 [62305]
        Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
        complexed with nad, pyr
      2. 1939008Domain d1ie3b2: 1ie3 B:146-312 [62307]
        Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
        complexed with nad, pyr
      3. 1939009Domain d1ie3c2: 1ie3 C:146-312 [62309]
        Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
        complexed with nad, pyr
      4. 1939010Domain d1ie3d2: 1ie3 D:146-312 [62311]
        Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
        complexed with nad, pyr
    4. Domain for 2cmd:
  7. 1939011Flaveria bidentis, chloroplast [TaxId:4224] [56332] (1 PDB entry)
  8. 1939013Haloarcula marismortui [TaxId:2238] [56335] (5 PDB entries)
    1. Domains for 1d3a:
      1. 1939022Domain d1d3aa2: 1d3a A:163-330 [42110]
        Other proteins in same PDB: d1d3aa1, d1d3ab1
        complexed with cl, na
      2. 1939023Domain d1d3ab2: 1d3a B:163-330 [42111]
        Other proteins in same PDB: d1d3aa1, d1d3ab1
        complexed with cl, na
    2. Domains for 1hlp:
      1. 1939024Domain d1hlpa2: 1hlp A:163-328 [42112]
        Other proteins in same PDB: d1hlpa1, d1hlpb1
        complexed with nad
      2. 1939025Domain d1hlpb2: 1hlp B:163-328 [42113]
        Other proteins in same PDB: d1hlpa1, d1hlpb1
        complexed with nad
    3. Domains for 1o6z:
      1. 1939014Domain d1o6za2: 1o6z A:163-330 [81108]
        Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
        complexed with cl, nad; mutant
      2. 1939015Domain d1o6zb2: 1o6z B:163-330 [81110]
        Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
        complexed with cl, nad; mutant
      3. 1939016Domain d1o6zc2: 1o6z C:163-330 [81112]
        Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
        complexed with cl, nad; mutant
      4. 1939017Domain d1o6zd2: 1o6z D:163-330 [81114]
        Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
        complexed with cl, nad; mutant
    4. Domains for 2hlp:
      1. 1939018Domain d2hlpa2: 2hlp A:163-330 [42108]
        Other proteins in same PDB: d2hlpa1, d2hlpb1
        complexed with cl, na; mutant
      2. 1939019Domain d2hlpb2: 2hlp B:163-330 [42109]
        Other proteins in same PDB: d2hlpa1, d2hlpb1
        complexed with cl, na; mutant
    5. Domains for 2x0r:
      1. 1939020Domain d2x0ra2: 2x0r A:163-330 [169771]
        Other proteins in same PDB: d2x0ra1, d2x0rb1
        complexed with cl, na, nad; mutant
      2. 1939021Domain d2x0rb2: 2x0r B:163-330 [169773]
        Other proteins in same PDB: d2x0ra1, d2x0rb1
        complexed with cl, na, nad; mutant
  9. 1939026Pig (Sus scrofa) [TaxId:9823] [56330] (3 PDB entries)
    1. Domains for 1mld:
      1. 1939027Domain d1mlda2: 1mld A:145-313 [42089]
        Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
        complexed with cit
      2. 1939028Domain d1mldb2: 1mld B:145-313 [42090]
        Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
        complexed with cit
      3. 1939029Domain d1mldc2: 1mld C:145-313 [42091]
        Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
        complexed with cit
      4. 1939030Domain d1mldd2: 1mld D:145-313 [42092]
        Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
        complexed with cit
    2. Domains for 4mdh:
      1. 1939033Domain d4mdha2: 4mdh A:155-333 [42095]
        Other proteins in same PDB: d4mdha1, d4mdhb1
        complexed with nad, so4
      2. 1939034Domain d4mdhb2: 4mdh B:155-333 [42096]
        Other proteins in same PDB: d4mdha1, d4mdhb1
        complexed with nad, so4
    3. Domains for 5mdh:
      1. 1939031Domain d5mdha2: 5mdh A:155-333 [42093]
        Other proteins in same PDB: d5mdha1, d5mdhb1
        complexed with mak, nad
      2. 1939032Domain d5mdhb2: 5mdh B:155-333 [42094]
        Other proteins in same PDB: d5mdha1, d5mdhb1
        complexed with mak, nad
  10. 1939035Sorghum (Sorghum vulgare), chloroplast [TaxId:4558] [56331] (1 PDB entry)
  11. 1939040Thermus flavus [TaxId:274] [56334] (2 PDB entries)
    1. Domains for 1bdm:
      1. 1939041Domain d1bdma2: 1bdm A:155-332 [42104]
        Other proteins in same PDB: d1bdma1, d1bdmb1
        complexed with nax; mutant
      2. 1939042Domain d1bdmb2: 1bdm B:155-332 [42105]
        Other proteins in same PDB: d1bdma1, d1bdmb1
        complexed with nax; mutant
    2. Domains for 1bmd:
      1. 1939043Domain d1bmda2: 1bmd A:155-332 [42106]
        Other proteins in same PDB: d1bmda1, d1bmdb1
        complexed with nad
      2. 1939044Domain d1bmdb2: 1bmd B:155-332 [42107]
        Other proteins in same PDB: d1bmda1, d1bmdb1
        complexed with nad
  12. 1939045Thermus thermophilus [TaxId:274] [82806] (7 PDB entries)
    identical sequence to that from the Thermus flavus enzyme
    1. Domains for 1iz9:
      1. 1939054Domain d1iz9a2: 1iz9 A:155-327 [76985]
        Other proteins in same PDB: d1iz9a1, d1iz9b1
      2. 1939055Domain d1iz9b2: 1iz9 B:155-327 [76987]
        Other proteins in same PDB: d1iz9a1, d1iz9b1
    2. Domains for 1wze:
      1. 1939050Domain d1wzea2: 1wze A:154-332 [121496]
        Other proteins in same PDB: d1wzea1, d1wzeb1
        automated match to d1y7ta2
        complexed with nad
      2. 1939051Domain d1wzeb2: 1wze B:154-332 [121498]
        Other proteins in same PDB: d1wzea1, d1wzeb1
        automated match to d1y7ta2
        complexed with nad
    3. Domains for 1wzi:
      1. 1939052Domain d1wzia2: 1wzi A:154-332 [121504]
        Other proteins in same PDB: d1wzia1, d1wzib1
        automated match to d1y7ta2
        complexed with ndp
      2. 1939053Domain d1wzib2: 1wzi B:154-332 [121506]
        Other proteins in same PDB: d1wzia1, d1wzib1
        automated match to d1y7ta2
        complexed with ndp
    4. Domains for 1y7t:
      1. 1939046Domain d1y7ta2: 1y7t A:154-332 [122719]
        Other proteins in same PDB: d1y7ta1, d1y7tb1
        automated match to d1iz9a2
        complexed with ndp, trs
      2. 1939047Domain d1y7tb2: 1y7t B:154-332 [122721]
        Other proteins in same PDB: d1y7ta1, d1y7tb1
        automated match to d1iz9a2
        complexed with ndp, trs
    5. Domains for 2cvq:
      1. 1939056Domain d2cvqa2: 2cvq A:154-332 [130886]
        Other proteins in same PDB: d2cvqa1, d2cvqb1
        automated match to d1iz9a2
        complexed with ndp, trs
      2. 1939057Domain d2cvqb2: 2cvq B:154-332 [130888]
        Other proteins in same PDB: d2cvqa1, d2cvqb1
        automated match to d1iz9a2
        complexed with ndp, trs
    6. Domains for 4kde:
      1. 1939048Domain d4kdea2: 4kde A:155-331 [236586]
        Other proteins in same PDB: d4kdea1, d4kdeb1
        automated match to d1wzea2
      2. 1939049Domain d4kdeb2: 4kde B:155-329 [236589]
        Other proteins in same PDB: d4kdea1, d4kdeb1
        automated match to d1wzea2
    7. Domains for 4kdf:
      1. 1939058Domain d4kdfa2: 4kdf A:155-326 [236591]
        Other proteins in same PDB: d4kdfa1, d4kdfb1, d4kdfc1, d4kdfd1
        automated match to d1wzea2
        complexed with so4
      2. 1939059Domain d4kdfd2: 4kdf D:155-326 [236587]
        Other proteins in same PDB: d4kdfa1, d4kdfb1, d4kdfc1, d4kdfd1
        automated match to d1wzea2
        complexed with so4

More info for Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

Timeline for Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain: