Lineage for Protein: Malate dehydrogenase

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 737029Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 737030Superfamily d.162.1: LDH C-terminal domain-like [56327] (2 families) (S)
  5. 737031Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (4 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
  6. 737139Protein Malate dehydrogenase [56329] (11 species)

Species:

  1. 737140Aquaspirillum arcticum [TaxId:87645] [56336] (3 PDB entries)
    1. Domain for 1b8p:
    2. Domain for 1b8u:
    3. Domain for 1b8v:
  2. 737144Archaeon Haloarcula marismortui [TaxId:2238] [56335] (8 PDB entries)
    1. Domains for 1d3a:
      1. 737163Domain d1d3aa2: 1d3a A:163-330 [42110]
        Other proteins in same PDB: d1d3aa1, d1d3ab1
      2. 737164Domain d1d3ab2: 1d3a B:163-330 [42111]
        Other proteins in same PDB: d1d3aa1, d1d3ab1
        complexed with cl, na
    2. Domains for 1gt2:
      1. 737167Domain d1gt2a2: 1gt2 A:163-330 [76339]
        Other proteins in same PDB: d1gt2a1, d1gt2b1
      2. 737168Domain d1gt2b2: 1gt2 B:163-330 [76341]
        Other proteins in same PDB: d1gt2a1, d1gt2b1
        complexed with cl, na, nad; mutant
    3. Domains for 1hlp:
      1. 737165Domain d1hlpa2: 1hlp A:163-328 [42112]
        Other proteins in same PDB: d1hlpa1, d1hlpb1
      2. 737166Domain d1hlpb2: 1hlp B:163-328 [42113]
        Other proteins in same PDB: d1hlpa1, d1hlpb1
        complexed with nad
    4. Domains for 1o6z:
      1. 737157Domain d1o6za2: 1o6z A:163-330 [81108]
        Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
      2. 737158Domain d1o6zb2: 1o6z B:163-330 [81110]
        Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
      3. 737159Domain d1o6zc2: 1o6z C:163-330 [81112]
        Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
      4. 737160Domain d1o6zd2: 1o6z D:163-330 [81114]
        Other proteins in same PDB: d1o6za1, d1o6zb1, d1o6zc1, d1o6zd1
        complexed with cl, nad; mutant
    5. Domains for 2hlp:
      1. 737161Domain d2hlpa2: 2hlp A:163-330 [42108]
        Other proteins in same PDB: d2hlpa1, d2hlpb1
      2. 737162Domain d2hlpb2: 2hlp B:163-330 [42109]
        Other proteins in same PDB: d2hlpa1, d2hlpb1
    6. Domains for 2j5k:
      1. 737145Domain d2j5ka2: 2j5k A:164-330 [138038]
        Other proteins in same PDB: d2j5ka1, d2j5kb1, d2j5kc1, d2j5kd1
        automatically matched to d1d3aa2
        complexed with cl
      2. 737146Domain d2j5kb2: 2j5k B:164-330 [138040]
        Other proteins in same PDB: d2j5ka1, d2j5kb1, d2j5kc1, d2j5kd1
        automatically matched to d1d3aa2
        complexed with cl
      3. 737147Domain d2j5kc2: 2j5k C:164-330 [138042]
        Other proteins in same PDB: d2j5ka1, d2j5kb1, d2j5kc1, d2j5kd1
        automatically matched to d1d3aa2
        complexed with cl
      4. 737148Domain d2j5kd2: 2j5k D:164-330 [138044]
        Other proteins in same PDB: d2j5ka1, d2j5kb1, d2j5kc1, d2j5kd1
        automatically matched to d1d3aa2
        complexed with cl
    7. Domains for 2j5q:
      1. 737149Domain d2j5qa2: 2j5q A:164-330 [138052]
        Other proteins in same PDB: d2j5qa1, d2j5qb1, d2j5qc1, d2j5qd1
        automatically matched to d1d3aa2
        complexed with cl
      2. 737150Domain d2j5qb2: 2j5q B:164-330 [138054]
        Other proteins in same PDB: d2j5qa1, d2j5qb1, d2j5qc1, d2j5qd1
        automatically matched to d1d3aa2
        complexed with cl
      3. 737151Domain d2j5qc2: 2j5q C:164-330 [138056]
        Other proteins in same PDB: d2j5qa1, d2j5qb1, d2j5qc1, d2j5qd1
        automatically matched to d1d3aa2
        complexed with cl
      4. 737152Domain d2j5qd2: 2j5q D:164-330 [138058]
        Other proteins in same PDB: d2j5qa1, d2j5qb1, d2j5qc1, d2j5qd1
        automatically matched to d1d3aa2
        complexed with cl
    8. Domains for 2j5r:
      1. 737153Domain d2j5ra2: 2j5r A:164-330 [138060]
        Other proteins in same PDB: d2j5ra1, d2j5rb1, d2j5rc1, d2j5rd1
        automatically matched to d1d3aa2
        complexed with cl
      2. 737154Domain d2j5rb2: 2j5r B:164-330 [138062]
        Other proteins in same PDB: d2j5ra1, d2j5rb1, d2j5rc1, d2j5rd1
        automatically matched to d1d3aa2
        complexed with cl
      3. 737155Domain d2j5rc2: 2j5r C:164-330 [138064]
        Other proteins in same PDB: d2j5ra1, d2j5rb1, d2j5rc1, d2j5rd1
        automatically matched to d1d3aa2
        complexed with cl
      4. 737156Domain d2j5rd2: 2j5r D:164-330 [138066]
        Other proteins in same PDB: d2j5ra1, d2j5rb1, d2j5rc1, d2j5rd1
        automatically matched to d1d3aa2
        complexed with cl
  3. 737169Chlorobium tepidum [TaxId:1097] [69841] (1 PDB entry)
  4. 737172Chlorobium vibrioforme [TaxId:1098] [69842] (2 PDB entries)
    1. Domains for 1guz:
      1. 737177Domain d1guza2: 1guz A:143-305 [65587]
        Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
      2. 737178Domain d1guzb2: 1guz B:143-305 [65589]
        Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
      3. 737179Domain d1guzc2: 1guz C:143-305 [65591]
        Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
      4. 737180Domain d1guzd2: 1guz D:143-305 [65593]
        Other proteins in same PDB: d1guza1, d1guzb1, d1guzc1, d1guzd1
        complexed with nad
    2. Domains for 1gv1:
      1. 737173Domain d1gv1a2: 1gv1 A:143-305 [65599]
        Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
      2. 737174Domain d1gv1b2: 1gv1 B:143-299 [65601]
        Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
      3. 737175Domain d1gv1c2: 1gv1 C:143-305 [65603]
        Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
      4. 737176Domain d1gv1d2: 1gv1 D:143-302 [65605]
        Other proteins in same PDB: d1gv1a1, d1gv1b1, d1gv1c1, d1gv1d1
  5. 737181Chloroflexus aurantiacus [TaxId:1108] [69840] (7 PDB entries)
    1. Domains for 1guy:
      1. 737188Domain d1guya2: 1guy A:144-306 [65583]
        Other proteins in same PDB: d1guya1, d1guyc1
      2. 737189Domain d1guyc2: 1guy C:144-306 [65585]
        Other proteins in same PDB: d1guya1, d1guyc1
        complexed with cd, nad
    2. Domains for 1ur5:
      1. 737184Domain d1ur5a2: 1ur5 A:144-308 [99808]
        Other proteins in same PDB: d1ur5a1, d1ur5c1
      2. 737185Domain d1ur5c2: 1ur5 C:144-309 [99810]
        Other proteins in same PDB: d1ur5a1, d1ur5c1
        complexed with cd, cl, na, nad; mutant
    3. Domains for 1uxg:
      1. 737190Domain d1uxga2: 1uxg A:144-307 [108101]
        Other proteins in same PDB: d1uxga1, d1uxgb1
      2. 737191Domain d1uxgb2: 1uxg B:144-307 [108103]
        Other proteins in same PDB: d1uxga1, d1uxgb1
        complexed with fmr, nad; mutant
    4. Domains for 1uxh:
      1. 737192Domain d1uxha2: 1uxh A:144-307 [108105]
        Other proteins in same PDB: d1uxha1, d1uxhb1
      2. 737193Domain d1uxhb2: 1uxh B:144-307 [108107]
        Other proteins in same PDB: d1uxha1, d1uxhb1
        complexed with fmr, nad; mutant
    5. Domains for 1uxi:
      1. 737194Domain d1uxia2: 1uxi A:144-307 [108109]
        Other proteins in same PDB: d1uxia1, d1uxib1
      2. 737195Domain d1uxib2: 1uxi B:144-307 [108111]
        Other proteins in same PDB: d1uxia1, d1uxib1
        complexed with fmr, na, nad; mutant
    6. Domains for 1uxj:
      1. 737182Domain d1uxja2: 1uxj A:144-307 [108113]
        Other proteins in same PDB: d1uxja1, d1uxjc1
      2. 737183Domain d1uxjc2: 1uxj C:144-307 [108115]
        Other proteins in same PDB: d1uxja1, d1uxjc1
        complexed with cd, cl, na, nad; mutant
    7. Domains for 1uxk:
      1. 737186Domain d1uxka2: 1uxk A:144-307 [108117]
        Other proteins in same PDB: d1uxka1, d1uxkc1
      2. 737187Domain d1uxkc2: 1uxk C:144-307 [108119]
        Other proteins in same PDB: d1uxka1, d1uxkc1
        complexed with cd, cl, na, nad; mutant
  6. 737196Escherichia coli [TaxId:562] [56333] (5 PDB entries)
    1. Domain for 1emd:
    2. Domains for 1ib6:
      1. 737203Domain d1ib6a2: 1ib6 A:146-312 [62147]
        Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
      2. 737204Domain d1ib6b2: 1ib6 B:146-312 [62149]
        Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
      3. 737205Domain d1ib6c2: 1ib6 C:146-312 [62151]
        Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
      4. 737206Domain d1ib6d2: 1ib6 D:146-312 [62153]
        Other proteins in same PDB: d1ib6a1, d1ib6b1, d1ib6c1, d1ib6d1
        complexed with nad, so4; mutant
    3. Domains for 1ie3:
      1. 737207Domain d1ie3a2: 1ie3 A:146-312 [62305]
        Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
      2. 737208Domain d1ie3b2: 1ie3 B:146-312 [62307]
        Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
      3. 737209Domain d1ie3c2: 1ie3 C:146-312 [62309]
        Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
      4. 737210Domain d1ie3d2: 1ie3 D:146-312 [62311]
        Other proteins in same PDB: d1ie3a1, d1ie3b1, d1ie3c1, d1ie3d1
        complexed with nad, pyr; mutant
    4. Domain for 2cmd:
    5. Domains for 2pwz:
      1. 737198Domain d2pwza2: 2pwz A:146-312 [139767]
        Other proteins in same PDB: d2pwza1, d2pwzc1, d2pwze1, d2pwzg1
        automatically matched to d1emd_2
      2. 737199Domain d2pwzc2: 2pwz C:146-312 [139769]
        Other proteins in same PDB: d2pwza1, d2pwzc1, d2pwze1, d2pwzg1
        automatically matched to d1emd_2
      3. 737200Domain d2pwze2: 2pwz E:146-312 [139771]
        Other proteins in same PDB: d2pwza1, d2pwzc1, d2pwze1, d2pwzg1
        automatically matched to d1emd_2
      4. 737201Domain d2pwzg2: 2pwz G:146-312 [139773]
        Other proteins in same PDB: d2pwza1, d2pwzc1, d2pwze1, d2pwzg1
        automatically matched to d1emd_2
  7. 737211Flaveria bidentis, chloroplast [TaxId:4224] [56332] (1 PDB entry)
  8. 737213Pig (Sus scrofa) [TaxId:9823] [56330] (3 PDB entries)
    1. Domains for 1mld:
      1. 737214Domain d1mlda2: 1mld A:145-313 [42089]
        Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
      2. 737215Domain d1mldb2: 1mld B:145-313 [42090]
        Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
      3. 737216Domain d1mldc2: 1mld C:145-313 [42091]
        Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
      4. 737217Domain d1mldd2: 1mld D:145-313 [42092]
        Other proteins in same PDB: d1mlda1, d1mldb1, d1mldc1, d1mldd1
        complexed with cit
    2. Domains for 4mdh:
      1. 737218Domain d4mdha2: 4mdh A:155-333 [42095]
        Other proteins in same PDB: d4mdha1, d4mdhb1
      2. 737219Domain d4mdhb2: 4mdh B:155-333 [42096]
        Other proteins in same PDB: d4mdha1, d4mdhb1
        complexed with nad, sul
    3. Domains for 5mdh:
      1. 737220Domain d5mdha2: 5mdh A:155-333 [42093]
        Other proteins in same PDB: d5mdha1, d5mdhb1
      2. 737221Domain d5mdhb2: 5mdh B:155-333 [42094]
        Other proteins in same PDB: d5mdha1, d5mdhb1
        complexed with mak, nad
  9. 737222Sorghum (Sorghum vulgare), chloroplast [TaxId:4558] [56331] (1 PDB entry)
  10. 737227Thermus flavus [TaxId:274] [56334] (2 PDB entries)
    1. Domains for 1bdm:
      1. 737228Domain d1bdma2: 1bdm A:155-332 [42104]
        Other proteins in same PDB: d1bdma1, d1bdmb1
      2. 737229Domain d1bdmb2: 1bdm B:155-332 [42105]
        Other proteins in same PDB: d1bdma1, d1bdmb1
        complexed with nax; mutant
    2. Domains for 1bmd:
      1. 737230Domain d1bmda2: 1bmd A:155-332 [42106]
        Other proteins in same PDB: d1bmda1, d1bmdb1
      2. 737231Domain d1bmdb2: 1bmd B:155-332 [42107]
        Other proteins in same PDB: d1bmda1, d1bmdb1
        complexed with nad
  11. 737232Thermus thermophilus [TaxId:274] [82806] (5 PDB entries)
    identical sequence to that from the Thermus flavus enzyme
    1. Domains for 1iz9:
      1. 737233Domain d1iz9a2: 1iz9 A:155-327 [76985]
        Other proteins in same PDB: d1iz9a1, d1iz9b1
      2. 737234Domain d1iz9b2: 1iz9 B:155-327 [76987]
        Other proteins in same PDB: d1iz9a1, d1iz9b1
    2. Domains for 1wze:
      1. 737237Domain d1wzea2: 1wze A:154-332 [121496]
        Other proteins in same PDB: d1wzea1, d1wzeb1
        automatically matched to d1iz9a2
        complexed with nad; mutant
      2. 737238Domain d1wzeb2: 1wze B:154-332 [121498]
        Other proteins in same PDB: d1wzea1, d1wzeb1
        automatically matched to d1iz9a2
        complexed with nad; mutant
    3. Domains for 1wzi:
      1. 737239Domain d1wzia2: 1wzi A:154-332 [121504]
        Other proteins in same PDB: d1wzia1, d1wzib1
        automatically matched to d1iz9a2
        complexed with ndp; mutant
      2. 737240Domain d1wzib2: 1wzi B:154-332 [121506]
        Other proteins in same PDB: d1wzia1, d1wzib1
        automatically matched to d1iz9a2
        complexed with ndp; mutant
    4. Domains for 1y7t:
      1. 737235Domain d1y7ta2: 1y7t A:154-332 [122719]
        Other proteins in same PDB: d1y7ta1, d1y7tb1
        automatically matched to d1iz9a2
        complexed with ndp, trs
      2. 737236Domain d1y7tb2: 1y7t B:154-332 [122721]
        Other proteins in same PDB: d1y7ta1, d1y7tb1
        automatically matched to d1iz9a2
        complexed with ndp, trs
    5. Domains for 2cvq:
      1. 737241Domain d2cvqa2: 2cvq A:154-332 [130886]
        Other proteins in same PDB: d2cvqa1, d2cvqb1
        automatically matched to d1iz9a2
        complexed with nap, trs
      2. 737242Domain d2cvqb2: 2cvq B:154-332 [130888]
        Other proteins in same PDB: d2cvqa1, d2cvqb1
        automatically matched to d1iz9a2
        complexed with nap, trs

More info for Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

Timeline for Protein Malate dehydrogenase from d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain: